Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras von Peeters, Ken, Van Leemputte, Frederik, Fischer, Baptiste, Bonini, Beatriz M., Quezada, Hector, Tsytlonok, Maksym, Haesen, Dorien, Vanthienen, Ward, Bernardes, Nuno, Gonzalez-Blas, Carmen Bravo, Janssens, Veerle, Tompa, Peter, Versées, Wim, Thevelein, Johan M.

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Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts von Guaitoli, Giambattista, Raimondi, Francesco, Gilsbach, Bernd K., Gómez-Llorente, Yacob, Deyaert, Egon, Renzi, Fabiana, Li, Xianting, Schaffner, Adam, Jagtap, Pravin Kumar Ankush, Boldt, Karsten, von Zweydorf, Felix, Gotthardt, Katja, Lorimer, Donald D., Yue, Zhenyu, Burgin, Alex, Janjic, Nebojsa, Sattler, Michael, Versées, Wim, Ueffing, Marius, Ubarretxena-Belandia, Iban, Kortholt, Arjan, Gloeckner, Christian Johannes

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The role of the essential GTPase ObgE in regulating lipopolysaccharide synthesis in Escherichia coli von Dewachter, Liselot, Deckers, Babette, Mares-Mejía, Israel, Louwagie, Elen, Vercauteren, Silke, Matthay, Paul, Brückner, Simon, Möller, Anna-Maria, Narberhaus, Franz, Vonesch, Sibylle C., Versées, Wim, Michiels, Jan

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Allosteric nanobodies to study the interactions between SOS1 and RAS von Fischer, Baptiste, Uchański, Tomasz, Sheryazdanova, Aidana, Gonzalez, Simon, Volkov, Alexander N., Brosens, Elke, Zögg, Thomas, Kalichuk, Valentina, Ballet, Steven, Versées, Wim, Sablina, Anna A., Pardon, Els, Wohlkönig, Alexandre, Steyaert, Jan

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Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2 von Singh, Ranjan K, Soliman, Ahmed, Guaitoli, Giambattista, Störmer, Eliza, von Zweydorf, Felix, Dal Maso, Thomas, Oun, Asmaa, Van Rillaer, Laura, Schmidt, Sven H, Chatterjee, Deep, David, Joshua A, Pardon, Els, Schwartz, Thomas U, Knapp, Stefan, Kennedy, Eileen J, Steyaert, Jan, Herberg, Friedrich W, Kortholt, Arjan, Gloeckner, Christian Johannes, Versées, Wim

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Allosteric Inhibition of Parkinson’s-Linked LRRK2 by Constrained Peptides von Helton, Leah G, Soliman, Ahmed, von Zweydorf, Felix, Kentros, Michalis, Manschwetus, Jascha T, Hall, Scotty, Gilsbach, Bernd, Ho, Franz Y, Athanasopoulos, Panagiotis S, Singh, Ranjan K, LeClair, Timothy J, Versées, Wim, Raimondi, Francesco, Herberg, Friedrich W, Gloeckner, Christian Johannes, Rideout, Hardy, Kortholt, Arjan, Kennedy, Eileen J

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A homologue of the Parkinson’s disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover von Deyaert, Egon, Wauters, Lina, Guaitoli, Giambattista, Konijnenberg, Albert, Leemans, Margaux, Terheyden, Susanne, Petrovic, Arsen, Gallardo, Rodrigo, Nederveen-Schippers, Laura M., Athanasopoulos, Panagiotis S., Pots, Henderikus, Van Haastert, Peter J. M., Sobott, Frank, Gloeckner, Christian Johannes, Efremov, Rouslan, Kortholt, Arjan, Versées, Wim

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Therapeutic Nanoreactors:  Combining Chemistry and Biology in a Novel Triblock Copolymer Drug Delivery System von Ranquin, An, Versées, Wim, Meier, Wolfgang, Steyaert, Jan, Van Gelder, Patrick

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ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family Member Bruchpilot von Miśkiewicz, Katarzyna, Jose, Liya E., Bento-Abreu, André, Fislage, Marcus, Taes, Ines, Kasprowicz, Jarosław, Swerts, Jef, Sigrist, Stephan, Versées, Wim, Robberecht, Wim, Verstreken, Patrik

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EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation von Bademosi, Adekunle T., Decet, Marianna, Kuenen, Sabine, Calatayud, Carles, Swerts, Jef, Gallego, Sandra F., Schoovaerts, Nils, Karamanou, Spyridoula, Louros, Nikolaos, Martin, Ella, Sibarita, Jean-Baptiste, Vints, Katlijn, Gounko, Natalia V., Meunier, Frédéric A., Economou, Anastassios, Versées, Wim, Rousseau, Frederic, Schymkowitz, Joost, Soukup, Sandra-F., Verstreken, Patrik

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The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis von Rosado, Leonardo Astolfi, Wahni, Khadija, Degiacomi, Giulia, Pedre, Brandán, Young, David, de la Rubia, Alfonso G., Boldrin, Francesca, Martens, Edo, Marcos-Pascual, Laura, Sancho-Vaello, Enea, Albesa-Jové, David, Provvedi, Roberta, Martin, Charlotte, Makarov, Vadim, Versées, Wim, Verniest, Guido, Guerin, Marcelo E., Mateos, Luis M., Manganelli, Riccardo, Messens, Joris

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The Universally Conserved Prokaryotic GTPases von VERSTRAETEN, Natalie, FAUVART, Maarten, VERSEES, Wim, MICHIELS, Jan

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Roco Proteins: GTPases with a Baroque Structure and Mechanism von Wauters, Lina, Versées, Wim, Kortholt, Arjan

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It Takes Two to Rule Translation Elongation von Versées, Wim

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Evaluation of Nucleoside Hydrolase Inhibitors for Treatment of African Trypanosomiasis von BERG, Maya, KOHL, Linda, GRELLIER, Philippe, HAEMERS, Achiel, DEGANO, Massimo, MAES, Louis, DE KONING, Harry P, AUGUSTYNS, Koen, VAN DER VEKEN, Pieter, JOOSSENS, Jurgen, AL-SALABI, Mohammed I, CASTAGNA, Valeria, GIANNESE, Francesca, COS, Paul, VERSEES, Wim, STEYAERT, Jan

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Structural insights into the GTP-driven monomerization and activation of a bacterial LRRK2 homolog using allosteric nanobodies von Galicia, Christian, Guaitoli, Giambattista, Fislage, Marcus, Gloeckner, Christian Johannes, Versées, Wim

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Deep mutational scanning of essential bacterial proteins can guide antibiotic development von Dewachter, Liselot, Brooks, Aaron N., Noon, Katherine, Cialek, Charlotte, Clark-ElSayed, Alia, Schalck, Thomas, Krishnamurthy, Nandini, Versées, Wim, Vranken, Wim, Michiels, Jan

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Single time-point analysis of product and substrate inhibition von Verlaine, Olivier, Malempré, Romain, Versées, Wim, Matagne, André, Frère, Jean-Marie

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Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance von Verstraeten, Natalie, Knapen, Wouter Joris, Kint, Cyrielle Ines, Liebens, Veerle, Van den Bergh, Bram, Dewachter, Liselot, Michiels, Joran Elie, Fu, Qiang, David, Charlotte Claudia, Fierro, Ana Carolina, Marchal, Kathleen, Beirlant, Jan, Versées, Wim, Hofkens, Johan, Jansen, Maarten, Fauvart, Maarten, Michiels, Jan

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Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates von Somme, Jonathan, Van Laer, Bart, Roovers, Martine, Steyaert, Jan, Versées, Wim, Droogmans, Louis

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