Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase von BUCKNER, F. S, VERLINDE, C. L. M. J, LA FLAMME, A. C, VAN VOORHUIS, W. C

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Structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from trypanosoma brucei determined from Laue data von Vellieux, F.M.D. (University of Groningen, Groningen, Netherlands), Hajdu, J, Verlinde, C.L.M.J, Groenduk, H, Read, R.J, Greenhough, T.J, Campbell, J.W, Kalk, K.H, Littlechild, J.A, Watson, H.C

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Selective Tight Binding Inhibitors of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase via Structure-Based Drug Design von Aronov, Alex M, Verlinde, Christophe L. M. J, Hol, Wim G. J, Gelb, Michael H

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The Role of Waters in Docking Strategies with Incremental Flexibility for Carbohydrate Derivatives:  Heat-Labile Enterotoxin, a Multivalent Test Case von Minke, Wendy E, Diller, David J, Hol, Wim G. J, Verlinde, Christophe L. M. J

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Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors von Suresh, Stephen, Bressi, Jerome C, Kennedy, Kevin J, Verlinde, Christophe L.M.J, Gelb, Michael H, Hol, Wim G.J

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Selective Inhibition of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase by Protein Structure-Based Design: Toward New Drugs for the Treatment of Sleeping Sickness von Verlinde, Christophe L. M. J, Callens, Mia, Van Calenbergh, Serge, Van Aerschot, Arthur, Herdewijn, Piet, Hannaert, Veronique, Michels, Paul A. M, Opperdoes, Fred R, Hol, Wim G. J

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Synthesis and Structure-Activity Relationships of Analogs of 2'-Deoxy-2'-(3-methoxybenzamido)adenosine, a Selective Inhibitor of Trypanosomal Glycosomal Glyceraldehyde-3-phosphate... von Van Calenbergh, Serge, Verlinde, Christophe L. M. J, Soenens, Johanna, De Bruyn, Andre, Callens, Mia, Blaton, Norbert M, Peeters, Oswald M, Herdewijn, Piet, Rozenski, Jef, Hol, Wim G. J

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314 MOLECULAR MODELING OF FARNESYLTRANSFERASE INHIBITORS FOR MALARIA THERAPEUTICS von Vigna, K. L., Hucke, O., Eastman, R., Verlinde, C. L., Van Voorhis, W. C.

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Glycolysis as a target for the design of new anti-trypanosome drugs von Verlinde, Christophe L.M.J., Hannaert, Véronique, Blonski, Casimir, Willson, Michèle, Périé, Jacques J., Fothergill-Gilmore, Linda A., Opperdoes, Fred R., Gelb, Michael H., Hol, Wim G.J., Michels, Paul A.M.

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Adenosine Analogues as Selective Inhibitors of Glyceraldehyde-3-phosphate Dehydrogenase of Trypanosomatidae via Structure-Based Drug Design von Bressi, Jerome C, Verlinde, Christophe L. M. J, Aronov, Alex M, Shaw, My Le, Shin, Sam S, Nguyen, Lisa N, Suresh, Stephen, Buckner, Frederick S, Van Voorhis, Wesley C, Kuntz, Irwin D, Hol, Wim G. J, Gelb, Michael H

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Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin von Haeseleer, F, Sokal, I, Verlinde, C L, Erdjument-Bromage, H, Tempst, P, Pronin, A N, Benovic, J L, Fariss, R N, Palczewski, K

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AB(5) toxins: structures and inhibitor design von Fan, E, Merritt, E A, Verlinde, C L, Hol, W G

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Structure-Based Exploration of the Ganglioside GM1 Binding Sites of Escherichia coli Heat-Labile Enterotoxin and Cholera Toxin for the Discovery of Receptor Antagonists von Minke, Wendy E, Roach, Claudia, Hol, Wim G. J, Verlinde, Christophe L. M. J

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Protein crystallography and infectious diseases von Verlinde, Christophe L.M.J., Merritt, Ethan A., Van Den Akker, Focco, Kim, Hidong, Feil, Ingeborg, Delboni, Luis F., Mande, Shekhar C., Sarfaty, Steve, Petra, Philip H., Hol, Wim G.J.

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Structure-Based Design of Submicromolar, Biologically Active Inhibitors of Trypanosomatid Glyceraldehyde-3-Phosphate Dehydrogenase von Aronov, Alex M., Suresh, Stephen, Buckner, Frederick S., Van Voorhis, Wesley C., Christophe L. M. J. Verlinde, Opperdoes, Fred R., Wim G. J. Hol, Gelb, Michael H.

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Structure-based drug design: progress, results and challenges von Verlinde, Christophe LMJ, Hol, Wim GJ

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Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phos... von Noble, Martin E. M, Verlinde, Christophe L. M. J, Groendijk, Hillie, Kalk, Kor H, Wierenga, Rik K, Hol, Wim G. J

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Crystal Structure of Glycosomal Glyceraldehyde-3-phosphate Dehydrogenase from Leishmania mexicana: Implications for Structure-Based Drug Design and a New Position for the Inorganic... von Kim, Hidong, Feil, Ingeborg K, Verlinde, Christophe L. M. J, Petra, Philip H, Hol, Wim G. J

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Structure of the complex between trypanosomal triosephosphate isomerase and N‐hydroxy‐4‐phosphono‐butanamide: Binding at the active site despite an “open” flexible loop conformatio... von Verlinde, Christophe L.M.J., Witmans, Cornelis J., Pijning, Tjaard, Kalk, Kor H., Hol, Wim G.J., Callens, Mia, Opperdoes, Fred R.

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Structure and absolute configuration of two stereoisomers of α,α'-[iminobis-(methylene)]bis(3,4-dihydro-2H-1-benzopyran-2-methanol) hydrobromide von Peeters, O. M., Verlinde, C. L., Blaton, N. M., De Ranter, C. J.

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