Optimizing intravenous drug administration by applying pharmacokinetic/pharmacodynamic concepts von Struys, M.M.R.F., Sahinovic, M., Lichtenbelt, B.J., Vereecke, H.E.M., Absalom, A.R.

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Frontal electroencephalogram based drug, sex, and age independent sedation level prediction using non-linear machine learning algorithms von Ramaswamy, S. M., Kuizenga, M. H., Weerink, M. A. S., Vereecke, H. E. M., Struys, M. M. R. F., Belur Nagaraj, S.

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Comparison of haemodynamic- and electroencephalographic-monitored effects evoked by four combinations of effect-site concentrations of propofol and remifentanil, yielding a predict... von van den Berg, J. P., Absalom, A. R., Venema, A. M., Kalmar, A. F., Van Amsterdam, K., Hannivoort, L. N., Proost, J. H., Meier, S., Scheeren, T. W. L., Struys, M. M. R. F., Vereecke, H. E. M.

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Study of the time course of the clinical effect of propofol compared with the time course of the predicted effect-site concentration: performance of three pharmacokinetic–dynamic m... von Coppens, M., Van Limmen, J.G.M., Schnider, T., Wyler, B., Bonte, S., Dewaele, F., Struys, M.M.R.F., Vereecke, H.E.M.

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Dexmedetomidine pharmacokinetic–pharmacodynamic modelling in healthy volunteers: 1. Influence of arousal on bispectral index and sedation von Colin, P.J., Hannivoort, L.N., Eleveld, D.J., Reyntjens, K.M.E.M., Absalom, A.R., Vereecke, H.E.M., Struys, M.M.R.F.

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Test of neural inertia in humans during general anaesthesia von Kuizenga, M.H., Colin, P.J., Reyntjens, K.M.E.M., Touw, D.J., Nalbat, H., Knotnerus, F.H., Vereecke, H.E.M., Struys, M.M.R.F.

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Dexmedetomidine pharmacodynamics in healthy volunteers: 2. Haemodynamic profile von Colin, P.J., Hannivoort, L.N., Eleveld, D.J., Reyntjens, K.M.E.M., Absalom, A.R., Vereecke, H.E.M., Struys, M.M.R.F.

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Pharmacokinetic and pharmacodynamic interactions in anaesthesia. A review of current knowledge and how it can be used to optimize anaesthetic drug administration von van den Berg, J.P., Vereecke, H.E.M., Proost, J.H., Eleveld, D.J., Wietasch, J.K.G., Absalom, A.R., Struys, M.M.R.F.

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Probability to tolerate laryngoscopy and noxious stimulation response index as general indicators of the anaesthetic potency of sevoflurane, propofol, and remifentanil von Hannivoort, L.N., Vereecke, H.E.M., Proost, J.H., Heyse, B.E.K., Eleveld, D.J., Bouillon, T.W., Struys, M.M.R.F., Luginbühl, M

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Comparing the haemodynamic effects of high- and low-dose opioid anaesthesia: a secondary analysis of a randomised controlled trial von Marges, O M, Nieboer, J P, de Keijzer, I N, Rettab, R, van Amsterdam, K, Scheeren, T W L, Absalom, A R A, Vereecke, H E M, Struys, M M R F, Vos, J J, van den Berg, J P

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A comparison of bispectral index and ARX‐derived auditory evoked potential index in measuring the clinical interaction between ketamine and propofol anaesthesia von Vereecke, H. E. M., Struys, M. M. R. F., Mortier, E. P.

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Corrigendum to ‘Study of the time course of the clinical effect of propofol compared with the time course of the predicted effect-site concentration: performance of three pharmacok... von Coppens, M., Van Limmen, J.G.M., Schnider, T., Wyler, B., Bonte, S., Dewaele, F., Struys, M.M.R.F., Vereecke, H.E.M.

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Comparison of haemodynamic- and electroencephalographic-monitored effects evoked by four combinations of effect-site concentrations of propofol and remifentanil, yielding a predict... von van den Berg, J. P, Absalom, A. R, Venema, A. M, Kalmar, Alain, Van Amsterdam, K, Hannivoort, L. N, Proost, J. H, Meier, S, Scheeren, T. W. L, Struys, Michel, Vereecke, H. E. M

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Auto-mutual information function of the EEG as a measure of depth of anesthesia von Julitta, B., Vallverdu, M., Melia, U. S. P., Tupaika, N., Jospin, M., Jensen, E. W., Struys, M. M. R. F., Vereecke, H. E. M., Caminal, P.

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Do all sedatives promote biological sleep electroencephalogram patterns? A machine learning framework to identify biological sleep promoting sedatives using electroencephalogram von Ramaswamy, Sowmya M, Kuizenga, Merel H, Weerink, Maud A S, Vereecke, Hugo E M, Nagaraj, Sunil B, Struys, Michel M R F

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Neural mass model-based tracking of anesthetic brain states von Kuhlmann, Levin, Freestone, Dean R., Manton, Jonathan H., Heyse, Bjorn, Vereecke, Hugo E.M., Lipping, Tarmo, Struys, Michel M.R.F., Liley, David T.J.

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Population Pharmacodynamics of Propofol and Sevoflurane in Healthy Volunteers Using a Clinical Score and the Patient State Index: A Crossover Study von Kuizenga, Merel H, Colin, Pieter J, Reyntjens, Koen M. E M, Touw, Daan J, Nalbat, Hasan, Knotnerus, Froukje H, Vereecke, Hugo E M, Struys, Michel M. R F

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Development of an Optimized Pharmacokinetic Model of Dexmedetomidine Using Target-controlled Infusion in Healthy Volunteers von Hannivoort, Laura N, Eleveld, Douglas J, Proost, Johannes H, Reyntjens, Koen M. E M, Absalom, Anthony R, Vereecke, Hugo E M, Struys, Michel M. R F

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Utility of the SmartPilot® View advisory screen to improve anaesthetic drug titration and postoperative outcomes in clinical practice: a two-centre prospective observational trial von Kuizenga, Merel H., Vereecke, Hugo E.M., Absalom, Anthony R., Bucher, Christian H., Hannivoort, Laura N., van den Berg, Johannes P., Schmalz, Livia, Struys, Michel M.R.F., Luginbühl, Martin

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Novel drug-independent sedation level estimation based on machine learning of quantitative frontal electroencephalogram features in healthy volunteers von Ramaswamy, Sowmya M., Kuizenga, Merel H., Weerink, Maud A.S., Vereecke, Hugo E.M., Struys, Michel M.R.F., Nagaraj, Sunil B.

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