Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia von Irving, Julie A.E., Enshaei, Amir, Parker, Catriona A., Sutton, Rosemary, Kuiper, Roland P., Erhorn, Amy, Minto, Lynne, Venn, Nicola C., Law, Tamara, Yu, Jiangyan, Schwab, Claire, Davies, Rosanna, Matheson, Elizabeth, Davies, Alysia, Sonneveld, Edwin, den Boer, Monique L., Love, Sharon B., Harrison, Christine J., Hoogerbrugge, Peter M., Revesz, Tamas, Saha, Vaskar, Moorman, Anthony V.

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Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL–USP2 fusions von Meyer, Claus, Lopes, Bruno A., Caye-Eude, Aurélie, Cavé, Hélène, Arfeuille, Chloé, Cuccuini, Wendy, Sutton, Rosemary, Venn, Nicola C., Oh, Seung Hwan, Tsaur, Grigory, Escherich, Gabriele, Feuchtinger, Tobias, Kosasih, Hansen J., Khaw, Seong L., Ekert, Paul G., Pombo-de-Oliveira, Maria S., Bidet, Audrey, Djahanschiri, Bardya, Ebersberger, Ingo, Zaliova, Marketa, Zuna, Jan, Zermanova, Zuzana, Juvonen, Vesa, Grümayer, Renate Panzer, Fazio, Grazia, Cazzaniga, Gianni, Larghero, Patrizia, Emerenciano, Mariana, Marschalek, Rolf

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The recombinome of IKZF1 deletions in B-cell precursor ALL von Lopes, Bruno A., Meyer, Claus, Bouzada, Heloysa, Külp, Marius, Maciel, Ana Luiza Tardem, Larghero, Patrizia, Barbosa, Thayana C., Poubel, Caroline P., Barbieri, Caroline, Venn, Nicola C., Pozza, Luciano Dalla, Barbaric, Draga, Palmi, Chiara, Fazio, Grazia, Saitta, Claudia, Aguiar, Thais F., Lins, Mecneide M., Ikoma-Colturato, Maura R. V., Schramm, Marcia, Chapchap, Eduardo, Cazzaniga, Gianni, Sutton, Rosemary, Marschalek, Rolf, Emerenciano, Mariana

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Targeted Next-Generation Sequencing for Detecting MLL Gene Fusions in Leukemia von Afrin, Sadia, Zhang, Christine R C, Meyer, Claus, Stinson, Caedyn L, Pham, Thy, Bruxner, Timothy J C, Venn, Nicola C, Trahair, Toby N, Sutton, Rosemary, Marschalek, Rolf, Fink, J Lynn, Moore, Andrew S

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Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia von Richmond, Jennifer, Carol, Hernan, Evans, Kathryn, High, Laura, Mendomo, Agnes, Robbins, Alissa, Meyer, Claus, Venn, Nicola C, Marschalek, Rolf, Henderson, Michelle, Sutton, Rosemary, Kurmasheva, Raushan T, Kees, Ursula R, Houghton, Peter J, Smith, Malcolm A, Lock, Richard B

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Improving the identification of high risk precursor B acute lymphoblastic leukemia patients with earlier quantification of minimal residual disease von Karsa, Mawar, Dalla Pozza, Luciano, Venn, Nicola C, Law, Tamara, Shi, Rachael, Giles, Jodie E, Bahar, Anita Y, Cross, Shamira, Catchpoole, Daniel, Haber, Michelle, Marshall, Glenn M, Norris, Murray D, Sutton, Rosemary

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The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias von Andersson, Anna K, Ma, Jing, Wang, Jianmin, Chen, Xiang, Gedman, Amanda Larson, Dang, Jinjun, Nakitandwe, Joy, Holmfeldt, Linda, Parker, Matthew, Easton, John, Huether, Robert, Kriwacki, Richard, Rusch, Michael, Wu, Gang, Li, Yongjin, Mulder, Heather, Raimondi, Susana, Pounds, Stanley, Kang, Guolian, Shi, Lei, Becksfort, Jared, Gupta, Pankaj, Payne-Turner, Debbie, Vadodaria, Bhavin, Boggs, Kristy, Yergeau, Donald, Manne, Jayanthi, Song, Guangchun, Edmonson, Michael, Nagahawatte, Panduka, Wei, Lei, Cheng, Cheng, Pei, Deqing, Sutton, Rosemary, Venn, Nicola C, Chetcuti, Albert, Rush, Amanda, Catchpoole, Daniel, Heldrup, Jesper, Fioretos, Thoas, Lu, Charles, Ding, Li, Pui, Ching-Hon, Shurtleff, Sheila, Mullighan, Charles G, Mardis, Elaine R, Wilson, Richard K, Gruber, Tanja A, Zhang, Jinghui, Downing, James R

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Monitoring of childhood ALL using BCR-ABL1 genomic breakpoints identifies a subgroup with CML-like biology von Hovorkova, Lenka, Zaliova, Marketa, Venn, Nicola C., Bleckmann, Kirsten, Trkova, Marie, Potuckova, Eliska, Vaskova, Martina, Linhartova, Jana, Machova Polakova, Katerina, Fronkova, Eva, Muskovic, Walter, Giles, Jodie E., Shaw, Peter J., Cario, Gunnar, Sutton, Rosemary, Stary, Jan, Trka, Jan, Zuna, Jan

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IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia von Lopes, Bruno A., Meyer, Claus, Barbosa, Thayana C., Poubel, Caroline P., Mansur, Marcela B., Duployez, Nicolas, Bashton, Matthew, Harrison, Christine J., zur Stadt, Udo, Horstmann, Martin, Pombo-de-Oliveira, Maria S., Palmi, Chiara, Cazzaniga, Gianni, Venn, Nicola C., Sutton, Rosemary, Alonso, Cristina N., Tsaur, Grigory, Gupta, Sanjeev K., Bakhshi, Sameer, Marschalek, Rolf, Emerenciano, Mariana

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Two novel cases of NUTM1‐rearranged B‐cell acute lymphoblastic leukaemia presenting with high‐risk features von McClure, Barbara J., Pal, Manika, Heatley, Susan L., Rehn, Jacqueline, Schutz, Caitlin, Breen, James, Venn, Nicola C., Sutton, Rosemary, Khaw, Seong Lin, Yeung, David T., White, Deborah L.

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Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia von Sutton, Rosemary, Shaw, Peter J., Venn, Nicola C., Law, Tamara, Dissanayake, Anuruddhika, Kilo, Tatjana, Haber, Michelle, Norris, Murray D., Fraser, Chris, Alvaro, Frank, Revesz, Tamas, Trahair, Toby N., Dalla‐Pozza, Luciano, Marshall, Glenn M., O'Brien, Tracey A.

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Outcomes for Australian children with relapsed/refractory acute lymphoblastic leukaemia treated with blinatumomab von Sutton, Rosemary, Pozza, Luciano Dalla, Khaw, Seong Lin, Fraser, Chris, Revesz, Tom, Chamberlain, Janis, Mitchell, Richard, Trahair, Toby N., Bateman, Caroline M., Venn, Nicola C., Law, Tamara, Ong, Erika, Heatley, Susan L., McClure, Barbara J., Meyer, Claus, Marschalek, Rolf, Henderson, Michelle J., Cross, Siobhan, White, Deborah L., Kotecha, Rishi S.

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Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions von Venn, Nicola C., Huang, Libby, Hovorková, Lenka, Muskovic, Walter, Wong, Marie, Law, Tamara, Heatley, Susan L., Khaw, Seong Lin, Revesz, Tom, Dalla Pozza, Luciano, Shaw, Peter J., Fraser, Chris, Moore, Andrew S., Cross, Siobhan, Bendak, Katerina, Norris, Murray D., Henderson, Michelle J., White, Deborah L., Cowley, Mark J., Trahair, Toby N., Zuna, Jan, Sutton, Rosemary

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Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma von Subhash, Vinod Vijay, Huang, Libby, Kamili, Alvin, Wong, Marie, Chen, Dan, Venn, Nicola C., Atkinson, Caroline, Mayoh, Chelsea, Venkat, Pooja, Tyrrell, Vanessa, Marshall, Glenn M., Cowley, Mark J., Ekert, Paul G., Norris, Murray D., Haber, Michelle, Henderson, Michelle J., Sutton, Rosemary, Fletcher, Jamie I., Trahair, Toby N.

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A risk score including microdeletions improves relapse prediction for standard and medium risk precursor B‐cell acute lymphoblastic leukaemia in children von Sutton, Rosemary, Venn, Nicola C., Law, Tamara, Boer, Judith M., Trahair, Toby N., Ng, Anthea, Den Boer, Monique L., Dissanayake, Anuruddhika, Giles, Jodie E., Dalzell, Pauline, Mayoh, Chelsea, Barbaric, Draga, Revesz, Tamas, Alvaro, Frank, Pieters, Rob, Haber, Michelle, Norris, Murray D., Schrappe, Martin, Dalla Pozza, Luciano, Marshall, Glenn M

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CKLF and IL1B transcript levels at diagnosis are predictive of relapse in children with pre‐B‐cell acute lymphoblastic leukaemia von Fitter, Stephen, Bradey, Alanah L., Kok, Chung Hoow, Noll, Jacqueline E., Wilczek, Vicki J., Venn, Nicola C., Law, Tamara, Paisitkriangkrai, Sakrapee, Story, Colin, Saunders, Lynda, Dalla Pozza, Luciano, Marshall, Glenn M., White, Deborah L., Sutton, Rosemary, Zannettino, Andrew C. W., Revesz, Tamas

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Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions von Sadras, Teresa, Heatley, Susan L., Kok, Chung H., Dang, Phuong, Galbraith, Kate M., McClure, Barbara J., Muskovic, Walter, Venn, Nicola C., Moore, Sarah, Osborn, Michael, Revesz, Tamas, Moore, Andrew S., Hughes, Timothy P., Yeung, David, Sutton, Rosemary, White, Deborah L.

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The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia von Brown, Lauren M., Lonsdale, Andrew, Zhu, Andrea, Davidson, Nadia M., Schmidt, Breon, Hawkins, Anthony, Wallach, Elise, Martin, Michelle, Mechinaud, Francoise M., Khaw, Seong Lin, Bartolo, Ray C., Ludlow, Louise E.A., Challis, Jackie, Brooks, Ian, Petrovic, Vida, Venn, Nicola C., Sutton, Rosemary, Majewski, Ian J., Oshlack, Alicia, Ekert, Paul G.

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Mechanism of relapse in pediatric acute lymphoblastic leukemia von Henderson, Michelle J., Choi, Seoyeon, Beesley, Alex H., Sutton, Rosemary, Venn, Nicola C., Marshall, Glenn M., Kee, Ursula R., Haber, Michelle, Norris, Murray D.

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Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia von Yadav, Babasaheb D, Samuels, Amy L, Wells, Julia E, Sutton, Rosemary, Venn, Nicola C, Bendak, Katerina, Anderson, Denise, Marshall, Glenn M, Cole, Catherine H, Beesley, Alex H, Kees, Ursula R, Lock, Richard B

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