Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease von Chalupova, Katarina, Korabecny, Jan, Bartolini, Manuela, Monti, Barbara, Lamba, Doriano, Caliandro, Rosanna, Pesaresi, Alessandro, Brazzolotto, Xavier, Gastellier, Anne-Julie, Nachon, Florian, Pejchal, Jaroslav, Jarosova, Michaela, Hepnarova, Vendula, Jun, Daniel, Hrabinova, Martina, Dolezal, Rafael, Zdarova Karasova, Jana, Mzik, Martin, Kristofikova, Zdena, Misik, Jan, Muckova, Lubica, Jost, Petr, Soukup, Ondrej, Benkova, Marketa, Setnicka, Vladimir, Habartova, Lucie, Chvojkova, Marketa, Kleteckova, Lenka, Vales, Karel, Mezeiova, Eva, Uliassi, Elisa, Valis, Martin, Nepovimova, Eugenie, Bolognesi, Maria Laura, Kuca, Kamil

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Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease von Svobodova, Barbora, Pulkrabkova, Lenka, Panek, Dawid, Misiachna, Anna, Kolcheva, Marharyta, Andrys, Rudolf, Handl, Jiri, Capek, Jan, Nyvltova, Pavlina, Rousar, Tomas, Prchal, Lukas, Hepnarova, Vendula, Hrabinova, Martina, Muckova, Lubica, Tosnerova, Daniela, Karabanovich, Galina, Finger, Vladimir, Soukup, Ondrej, Horak, Martin, Korabecny, Jan

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Development of versatile and potent monoquaternary reactivators of acetylcholinesterase von Gorecki, Lukas, Hepnarova, Vendula, Karasova, Jana Zdarova, Hrabinova, Martina, Courageux, Charlotte, Dias, José, Kucera, Tomas, Kobrlova, Tereza, Muckova, Lubica, Prchal, Lukas, Malinak, David, Jun, Daniel, Musilek, Kamil, Worek, Franz, Nachon, Florian, Soukup, Ondrej, Korabecny, Jan

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Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators von Malinak, David, Dolezal, Rafael, Hepnarova, Vendula, Hozova, Miroslava, Andrys, Rudolf, Bzonek, Petr, Racakova, Veronika, Korabecny, Jan, Gorecki, Lukas, Mezeiova, Eva, Psotka, Miroslav, Jun, Daniel, Kuca, Kamil, Musilek, Kamil

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Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors von Svobodova, Barbora, Mezeiova, Eva, Hepnarova, Vendula, Hrabinova, Martina, Muckova, Lubica, Kobrlova, Tereza, Jun, Daniel, Soukup, Ondrej, Jimeno, María Luisa, Marco-Contelles, José, Korabecny, Jan

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Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods von Janockova, Jana, Dolezal, Rafael, Nepovimova, Eugenie, Kobrlova, Tereza, Benkova, Marketa, Kuca, Kamil, Konecny, Jan, Mezeiova, Eva, Melikova, Michaela, Hepnarova, Vendula, Ring, Avi, Soukup, Ondrej, Korabecny, Jan

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A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rat von Jiří Kassa, Jana Hatlapatková, Jana Žďárová Karasová, Vendula Hepnarová, Filip Caisberger, Jaroslav Pejchal

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A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats von Kassa, Jiří, Hatlapatková, Jana, Žďárová Karasová, Jana, Hepnarová, Vendula, Caisberger, Filip, Pejchal, Jaroslav

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A-agents, misleadingly known as “Novichoks”: a narrative review von Opravil, Jakub, Pejchal, Jaroslav, Finger, Vladimir, Korabecny, Jan, Rozsypal, Tomas, Hrabinova, Martina, Muckova, Lubica, Hepnarova, Vendula, Konecny, Jan, Soukup, Ondrej, Jun, Daniel

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Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile von Sobolova, Katerina, Hrabinova, Martina, Hepnarova, Vendula, Kucera, Tomas, Kobrlova, Tereza, Benkova, Marketa, Janockova, Jana, Dolezal, Rafael, Prchal, Lukas, Benek, Ondrej, Mezeiova, Eva, Jun, Daniel, Soukup, Ondrej, Korabecny, Jan

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Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870 von Zdarova Karasova, Jana, Kassa, Jiri, Hepnarova, Vendula, Pejchal, Jaroslav, Junova, Lucie, Andrys, Rudolf, Malinak, David, Bzonek, Petr, Kohoutova, Zuzana, Musilek, Kamil

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A-series agent A-234: initial in vitro and in vivo characterization von Hrabinova, Martina, Pejchal, Jaroslav, Hepnarova, Vendula, Muckova, Lubica, Junova, Lucie, Opravil, Jakub, Zdarova Karasova, Jana, Rozsypal, Tomas, Dlabkova, Alzbeta, Rehulkova, Helena, Kucera, Tomas, Vecera, Zbyněk, Caisberger, Filip, Schmidt, Monika, Soukup, Ondrej, Jun, Daniel

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Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators von Hepnarova, Vendula, Muckova, Lubica, Ring, Avi, Pejchal, Jaroslav, Herman, David, Misik, Jan, Hrabinova, Martina, Jun, Daniel, Soukup, Ondrej

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Uncharged mono- and bisoximes: In search of a zwitterion to countermeasure organophosphorus intoxication von Gorecki, Lukas, Markova, Aneta, Hepnarova, Vendula, Zivna, Natalie, Junova, Lucie, Hrabinova, Martina, Janousek, Jiri, Kobrlova, Tereza, Prchal, Lukas, Jun, Daniel, Soukup, Ondrej, Horn, Gabriele, Worek, Franz, Marek, Jan, Korabecny, Jan

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Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides von Hepnarova, Vendula, Hrabinova, Martina, Muckova, Lubica, Kucera, Tomas, Schmidt, Monika, Dolezal, Rafael, Gorecki, Lukas, Hrabcova, Veronika, Korabecny, Jan, Mezeiova, Eva, Jun, Daniel, Pejchal, Jaroslav

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Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness von Zdarova Karasova, Jana, Hepnarova, Vendula, Andrys, Rudolf, Lisa, Miroslav, Jost, Petr, Muckova, Lubica, Pejchal, Jaroslav, Herman, David, Jun, Daniel, Kassa, Jiri, Kuca, Kamil

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7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo von Kaniakova, Martina, Korabecny, Jan, Holubova, Kristina, Kleteckova, Lenka, Chvojkova, Marketa, Hakenova, Kristina, Prchal, Lukas, Novak, Martin, Dolezal, Rafael, Hepnarova, Vendula, Svobodova, Barbora, Kucera, Tomas, Lichnerova, Katarina, Krausova, Barbora, Horak, Martin, Vales, Karel, Soukup, Ondrej

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Huprine Y – Tryptophan heterodimers with potential implication to Alzheimer’s disease treatment von Mezeiova, Eva, Hrabinova, Martina, Hepnarova, Vendula, Jun, Daniel, Janockova, Jana, Muckova, Lubica, Prchal, Lukas, Kristofikova, Zdena, Kucera, Tomas, Gorecki, Lukas, Chalupova, Katarina, Kunes, Jiri, Hroudova, Jana, Soukup, Ondrej, Korabecny, Jan

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Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer’s Disease von Gorecki, Lukas, Uliassi, Elisa, Bartolini, Manuela, Janockova, Jana, Hrabinova, Martina, Hepnarova, Vendula, Prchal, Lukas, Muckova, Lubica, Pejchal, Jaroslav, Karasova, Jana Z, Mezeiova, Eva, Benkova, Marketa, Kobrlova, Tereza, Soukup, Ondrej, Petralla, Sabrina, Monti, Barbara, Korabecny, Jan, Bolognesi, Maria Laura

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Structure-Guided Design of IN/I-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer’s Disease von Svobodova, Barbora, Pulkrabkova, Lenka, Panek, Dawid, Misiachna, Anna, Kolcheva, Marharyta, Andrys, Rudolf, Handl, Jiri, Capek, Jan, Nyvltova, Pavlina, Rousar, Tomas, Prchal, Lukas, Hepnarova, Vendula, Hrabinova, Ma, Muckova, Lubica, Tosnerova, Daniela, Karabanovich, Galina, Finger, Vladimir, Soukup, Ondrej, Horak, Ma, Korabecny, Jan

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