Notch3 Signaling and Aggregation as Targets for the Treatment of CADASIL and Other NOTCH3-Associated Small-Vessel Diseases von Schoemaker, Dorothee, Arboleda-Velasquez, Joseph F.

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Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease von Littau, Jessica Lisa, Velilla, Lina, Hase, Yoshiki, Villalba‐Moreno, Nelson David, Hagel, Christian, Drexler, Dagmar, Osorio Restrepo, Santiago, Villegas, Andres, Lopera, Francisco, Vargas, Sergio, Glatzel, Markus, Krasemann, Susanne, Quiroz, Yakeel T., Arboleda‐Velasquez, Joseph F., Kalaria, Rajesh, Sepulveda‐Falla, Diego

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Safe and Effective Disease-Modifying Therapies for Small Blood Vessel Disease in the Brain von Arboleda-Velasquez, Joseph F.

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APOE Christchurch‐mimetic therapeutic antibody reduces APOE‐mediated toxicity and tau phosphorylation von Marino, Claudia, Perez‐Corredor, Paula, O'Hare, Michael, Heuer, Annie, Chmielewska, Natalia, Gordon, Harper, Chandrahas, Anita S., Gonzalez‐Buendia, Lucia, Delgado‐Tirado, Santiago, Doan, Tri H., Vanderleest, Timothy E., Arevalo‐Alquichire, Said, Obar, Robert A., Ortiz‐Cordero, Carolina, Villegas, Andres, Sepulveda‐Falla, Diego, Kim, Leo A., Lopera, Francisco, Mahley, Robert, Huang, Yadong, Quiroz, Yakeel T., Arboleda‐Velasquez, Joseph F.

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Notch Signaling in Vascular Endothelial and Mural Cell Communications von O'Hare, Michael, Arboleda-Velasquez, Joseph F

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TNF‐α signaling regulates RUNX1 function in endothelial cells von Whitmore, Hannah A. B., Amarnani, Dhanesh, O'Hare, Michael, Delgado‐Tirado, Santiago, Gonzalez‐Buendia, Lucia, An, Miranda, Pedron, Julien, Bushweller, John H., Arboleda‐Velasquez, Joseph F., Kim, Leo A.

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Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report von Arboleda-Velasquez, Joseph F., Lopera, Francisco, O’Hare, Michael, Delgado-Tirado, Santiago, Marino, Claudia, Chmielewska, Natalia, Saez-Torres, Kahira L., Amarnani, Dhanesh, Schultz, Aaron P., Sperling, Reisa A., Leyton-Cifuentes, David, Chen, Kewei, Baena, Ana, Aguillon, David, Rios-Romenets, Silvia, Giraldo, Margarita, Guzmán-Vélez, Edmarie, Norton, Daniel J., Pardilla-Delgado, Enmanuelle, Artola, Arabiye, Sanchez, Justin S., Acosta-Uribe, Juliana, Lalli, Matthew, Kosik, Kenneth S., Huentelman, Matthew J., Zetterberg, Henrik, Blennow, Kaj, Reiman, Rebecca A., Luo, Ji, Chen, Yinghua, Thiyyagura, Pradeep, Su, Yi, Jun, Gyungah R., Naymik, Marcus, Gai, Xiaowu, Bootwalla, Moiz, Ji, Jianling, Shen, Lishuang, Miller, John B., Kim, Leo A., Tariot, Pierre N., Johnson, Keith A., Reiman, Eric M., Quiroz, Yakeel T.

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Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study von Quiroz, Yakeel T, Zetterberg, Henrik, Reiman, Eric M, Chen, Yinghua, Su, Yi, Fox-Fuller, Joshua T, Garcia, Gloria, Villegas, Andres, Sepulveda-Falla, Diego, Villada, Marina, Arboleda-Velasquez, Joseph F, Guzmán-Vélez, Edmarie, Vila-Castelar, Clara, Gordon, Brian A, Schultz, Stephanie A, Protas, Hillary D, Ghisays, Valentina, Giraldo, Margarita, Tirado, Victoria, Baena, Ana, Munoz, Claudia, Rios-Romenets, Silvia, Tariot, Pierre N, Blennow, Kaj, Lopera, Francisco

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Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease von Quiroz, Yakeel T, Sperling, Reisa A, Norton, Daniel J, Baena, Ana, Arboleda-Velasquez, Joseph F, Cosio, Danielle, Schultz, Aaron, Lapoint, Molly, Guzman-Velez, Edmarie, Miller, John B, Kim, Leo A, Chen, Kewei, Tariot, Pierre N, Lopera, Francisco, Reiman, Eric M, Johnson, Keith A

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Clinical and research applications of magnetic resonance imaging in the study of CADASIL von Schoemaker, Dorothee, Quiroz, Yakeel T., Torrico-Teave, Heirangi, Arboleda-Velasquez, Joseph F.

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Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy von Amarnani, Dhanesh, Machuca-Parra, Arturo Israel, Wong, Lindsay L, Marko, Christina K, Stefater, James A, Stryjewski, Tomasz P, Eliott, Dean, Arboleda-Velasquez, Joseph F, Kim, Leo A

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Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man von Lopera, Francisco, Marino, Claudia, Chandrahas, Anita S., O’Hare, Michael, Villalba-Moreno, Nelson David, Aguillon, David, Baena, Ana, Sanchez, Justin S., Vila-Castelar, Clara, Ramirez Gomez, Liliana, Chmielewska, Natalia, Oliveira, Gabriel M., Littau, Jessica Lisa, Hartmann, Kristin, Park, Kyungeun, Krasemann, Susanne, Glatzel, Markus, Schoemaker, Dorothee, Gonzalez-Buendia, Lucia, Delgado-Tirado, Santiago, Arevalo-Alquichire, Said, Saez-Torres, Kahira L., Amarnani, Dhanesh, Kim, Leo A., Mazzarino, Randall C., Gordon, Harper, Bocanegra, Yamile, Villegas, Andres, Gai, Xiaowu, Bootwalla, Moiz, Ji, Jianling, Shen, Lishuang, Kosik, Kenneth S., Su, Yi, Chen, Yinghua, Schultz, Aaron, Sperling, Reisa A., Johnson, Keith, Reiman, Eric M., Sepulveda-Falla, Diego, Arboleda-Velasquez, Joseph F., Quiroz, Yakeel T.

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Improving Criminal Responsibility Determinations Using Structured Professional Judgment von Acklin, Marvin W., Velasquez, Joseph P.

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The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation von Nelson, Maxine R., Liu, Peng, Agrawal, Ayushi, Yip, Oscar, Blumenfeld, Jessica, Traglia, Michela, Kim, Min Joo, Koutsodendris, Nicole, Rao, Antara, Grone, Brian, Hao, Yanxia, Yoon, Seo Yeon, Xu, Qin, De Leon, Samuel, Choenyi, Tenzing, Thomas, Reuben, Lopera, Francisco, Quiroz, Yakeel T., Arboleda-Velasquez, Joseph F., Reiman, Eric M., Mahley, Robert W., Huang, Yadong

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Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer’s disease von Sun, Guoqiang George, Wang, Cheng, Mazzarino, Randall C., Perez-Corredor, Paula Andrea, Davtyan, Hayk, Blurton-Jones, Mathew, Lopera, Francisco, Arboleda-Velasquez, Joseph F., Shi, Yanhong

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Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia von Sepulveda-Falla, Diego, Sanchez, Justin S., Almeida, Maria Camila, Boassa, Daniela, Acosta-Uribe, Juliana, Vila-Castelar, Clara, Ramirez-Gomez, Liliana, Baena, Ana, Aguillon, David, Villalba-Moreno, Nelson David, Littau, Jessica Lisa, Villegas, Andres, Beach, Thomas G., White, Charles L., Ellisman, Mark, Krasemann, Susanne, Glatzel, Markus, Johnson, Keith A., Sperling, Reisa A., Reiman, Eric M., Arboleda-Velasquez, Joseph F., Kosik, Kenneth S., Lopera, Francisco, Quiroz, Yakeel T.

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Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer’s disease von Langella, Stephanie, Barksdale, N. Gil, Vasquez, Daniel, Aguillon, David, Chen, Yinghua, Su, Yi, Acosta-Baena, Natalia, Acosta-Uribe, Juliana, Baena, Ana Y., Garcia-Ospina, Gloria, Giraldo-Chica, Margarita, Tirado, Victoria, Muñoz, Claudia, Ríos-Romenets, Silvia, Guzman-Martínez, Claudia, Oliveira, Gabriel, Yang, Hyun-Sik, Vila-Castelar, Clara, Pruzin, Jeremy J., Ghisays, Valentina, Arboleda-Velasquez, Joseph F., Kosik, Kenneth S., Reiman, Eric M., Lopera, Francisco, Quiroz, Yakeel T.

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Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis von Lam, Jonathan D, Oh, Daniel J, Wong, Lindsay L, Amarnani, Dhanesh, Park-Windhol, Cindy, Sanchez, Angie V, Cardona-Velez, Jonathan, McGuone, Declan, Stemmer-Rachamimov, Anat O, Eliott, Dean, Bielenberg, Diane R, van Zyl, Tave, Shen, Lishuang, Gai, Xiaowu, D'Amore, Patricia A, Kim, Leo A, Arboleda-Velasquez, Joseph F

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Heparin treatment is associated with a delayed diagnosis of Alzheimer's dementia in electronic health records from two large United States health systems von Readhead, Benjamin, Klang, Eyal, Gisladottir, Undina, Vandromme, Maxence, Li, Li, Quiroz, Yakeel T, Arboleda-Velasquez, Joseph F, Dudley, Joel T, Tatonetti, Nicholas P, Glicksberg, Benjamin S, Reiman, Eric M

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Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL von Machuca-Parra, Arturo I, Bigger-Allen, Alexander A, Sanchez, Angie V, Boutabla, Anissa, Cardona-Vélez, Jonathan, Amarnani, Dhanesh, Saint-Geniez, Magali, Siebel, Christian W, Kim, Leo A, D'Amore, Patricia A, Arboleda-Velasquez, Joseph F

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