EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair von Koyen, Allyson E., Madden, Matthew Z., Park, Dongkyoo, Minten, Elizabeth V., Kapoor-Vazirani, Priya, Werner, Erica, Pfister, Neil T., Haji-Seyed-Javadi, Ramona, Zhang, Hui, Xu, Jie, Deng, Nikita, Duong, Duc M., Pecen, Turner J., Frazier, Zoë, Nagel, Zachary D., Lazaro, Jean-Bernard, Mouw, Kent W., Seyfried, Nicholas T., Moreno, Carlos S., Owonikoko, Taofeek K., Deng, Xingming, Yu, David S.

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The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential von Friesen, Westley J, Johnson, Briana, Sierra, Jairo, Zhuo, Jin, Vazirani, Priya, Xue, Xiaojiao, Tomizawa, Yuki, Baiazitov, Ramil, Morrill, Christie, Ren, Hongyu, Babu, Suresh, Moon, Young-Choon, Branstrom, Art, Mollin, Anna, Hedrick, Jean, Sheedy, Josephine, Elfring, Gary, Weetall, Marla, Colacino, Joseph M, Welch, Ellen M, Peltz, Stuart W

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SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation von Minten, Elizabeth V., Kapoor-Vazirani, Priya, Li, Chunyang, Zhang, Hui, Balakrishnan, Kamakshi, Yu, David S.

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A Dual Role for the Histone Methyltransferase PR-SET7/SETD8 and Histone H4 Lysine 20 Monomethylation in the Local Regulation of RNA Polymerase II Pausing von Kapoor-Vazirani, Priya, Vertino, Paula M.

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SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks von Kapoor-Vazirani, Priya, Rath, Sandip K., Liu, Xu, Shu, Zhen, Bowen, Nicole E., Chen, Yitong, Haji-Seyed-Javadi, Ramona, Daddacha, Waaqo, Minten, Elizabeth V., Danelia, Diana, Farchi, Daniela, Duong, Duc M., Seyfried, Nicholas T., Deng, Xingming, Ortlund, Eric A., Kim, Baek, Yu, David S.

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SUV420H2-Mediated H4K20 Trimethylation Enforces RNA Polymerase II Promoter-Proximal Pausing by Blocking hMOF-Dependent H4K16 Acetylation von Kapoor-Vazirani, Priya, Kagey, Jacob D., Vertino, Paula M.

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Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins von Bowen, Nicole E., Temple, Joshua, Shepard, Caitlin, Oo, Adrian, Arizaga, Fidel, Kapoor-Vazirani, Priya, Persaud, Mirjana, Yu, Corey H., Kim, Dong-Hyun, Schinazi, Raymond F., Ivanov, Dmitri N., Diaz-Griffero, Felipe, Yu, David S., Xiong, Yong, Kim, Baek

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Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity von Kapoor-Vazirani, Priya, Kagey, Jacob D, Powell, Doris R, Vertino, Paula M

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Abstract PR-002: SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation von Minten, Elizabeth V., Kappor-Vazirani, Priya, Li, Chunyang, Zhang, Hui, Balakrishnan, Kamakshi, Yu, David S.

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SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy von Naryshkin, Nikolai A., Weetall, Marla, Dakka, Amal, Narasimhan, Jana, Zhao, Xin, Feng, Zhihua, Ling, Karen K. Y., Karp, Gary M., Qi, Hongyan, Woll, Matthew G., Chen, Guangming, Zhang, Nanjing, Gabbeta, Vijayalakshmi, Vazirani, Priya, Bhattacharyya, Anuradha, Furia, Bansri, Risher, Nicole, Sheedy, Josephine, Kong, Ronald, Ma, Jiyuan, Turpoff, Anthony, Lee, Chang-Sun, Zhang, Xiaoyan, Moon, Young-Choon, Trifillis, Panayiota, Welch, Ellen M., Colacino, Joseph M., Babiak, John, Almstead, Neil G., Peltz, Stuart W., Eng, Loren A., Chen, Karen S., Mull, Jesse L., Lynes, Maureen S., Rubin, Lee L., Fontoura, Paulo, Santarelli, Luca, Haehnke, Daniel, McCarthy, Kathleen D., Schmucki, Roland, Ebeling, Martin, Sivaramakrishnan, Manaswini, Ko, Chien-Ping, Paushkin, Sergey V., Ratni, Hasane, Gerlach, Irene, Ghosh, Anirvan, Metzger, Friedrich

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A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation von Duncan, Christopher G, Barwick, Benjamin G, Jin, Genglin, Rago, Carlo, Kapoor-Vazirani, Priya, Powell, Doris R, Chi, Jen-Tsan, Bigner, Darell D, Vertino, Paula M, Yan, Hai

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Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase von Subramanian, Krithika, Jia, Da, Kapoor-Vazirani, Priya, Powell, Doris R., Collins, Robert E., Sharma, Dipali, Peng, Junmin, Cheng, Xiaodong, Vertino, Paula M.

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Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy von Ratni, Hasane, Karp, Gary M, Weetall, Marla, Naryshkin, Nikolai A, Paushkin, Sergey V, Chen, Karen S, McCarthy, Kathleen D, Qi, Hongyan, Turpoff, Anthony, Woll, Matthew G, Zhang, Xiaoyan, Zhang, Nanjing, Yang, Tianle, Dakka, Amal, Vazirani, Priya, Zhao, Xin, Pinard, Emmanuel, Green, Luke, David-Pierson, Pascale, Tuerck, Dietrich, Poirier, Agnes, Muster, Wolfgang, Kirchner, Stephan, Mueller, Lutz, Gerlach, Irene, Metzger, Friedrich

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Guanidino quinazolines and pyrimidines promote readthrough of premature termination codons in cells with native nonsense mutations von Morrill, Christie, Friesen, Westley J., Babu, Suresh, Baiazitov, Ramil Y., Du, Wu, Karloff, Diane B., Lee, Chang-Sun, Moon, Young-Choon, Ren, Hongyu, Sierra, Jairo, Tomizawa, Yuki, Vazirani, Priya, Welch, Ellen M., Xue, Xiaojiao, Zhuo, Jin

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DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining von Head, PamelaSara E, Kapoor-Vazirani, Priya, Nagaraju, Ganji P, Zhang, Hui, Rath, Sandip K, Luong, Nho C, Haji-Seyed-Javadi, Ramona, Sesay, Fatmata, Wang, Shi-Ya, Duong, Duc M, Daddacha, Waaqo, Minten, Elizabeth V, Song, Boying, Danelia, Diana, Liu, Xu, Li, Shuyi, Ortlund, Eric A, Seyfried, Nicholas T, Smalley, David M, Wang, Ya, Deng, Xingming, Dynan, William S, El-Rayes, Bassel, Davis, Anthony J, Yu, David S

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Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy von Kagey, Jacob D, Kapoor-Vazirani, Priya, McCabe, Michael T, Powell, Doris R, Vertino, Paula M

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A heterozygous IDH1 super(R132H/WT) mutation induces genome-wide alterations in DNA methylation von Duncan, Christopher G, Barwick, Benjamin G, Jin, Genglin, Rago, Carlo, Kapoor-Vazirani, Priya, Powell, Doris R, Chi, Jen-Tsan, Bigner, Darell D, Vertino, Paula M, Yan, Hai

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A heterozygous IDH1 R132H/WT mutation induces genome-wide alterations in DNA methylation von Duncan, Christopher G., Barwick, Benjamin G., Jin, Genglin, Rago, Carlo, Kapoor-Vazirani, Priya, Powell, Doris R., Chi, Jen-Tsan, Bigner, Darell D., Vertino, Paula M., Yan, Hai

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Methylation-sensitive Regulation of TMS1/ASC by the Ets Factor, GA-binding Protein-α von Lucas, Mary E., Crider, Krista S., Powell, Doris R., Kapoor-Vazirani, Priya, Vertino, Paula M.

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Methylation-sensitive Regulation of TMS1/ASC by the Ets Factor, GA-binding Protein-{alpha} von Lucas, Mary E, Crider, Krista S, Powell, Doris R, Kapoor-Vazirani, Priya, Vertino, Paula M

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