The relationships between serum cytokine levels and tumor infiltrating immune cells and their clinical significance in colorectal cancer von Väyrynen, Juha P., Kantola, Tiina, Väyrynen, Sara A., Klintrup, Kai, Bloigu, Risto, Karhu, Toni, Mäkelä, Jyrki, Herzig, Karl‐Heinz, Karttunen, Tuomo J., Tuomisto, Anne, Mäkinen, Markus J.

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Ectopic crypt foci in conventional and serrated colorectal polyps von Väyrynen, Sara A, Väyrynen, Juha P, Klintrup, Kai, Mäkelä, Jyrki, Tuomisto, Anne, Mäkinen, Markus J

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Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma von Chung, Katherine Minjee, Singh, Jaffarguriqbal, Lawres, Lauren, Dorans, Kimberly Judith, Garcia, Cathy, Burkhardt, Daniel B., Robbins, Rebecca, Bhutkar, Arjun, Cardone, Rebecca, Zhao, Xiaojian, Babic, Ana, Vayrynen, Sara A., Dias Costa, Andressa, Nowak, Jonathan A., Chang, Daniel T., Dunne, Richard F., Hezel, Aram F., Koong, Albert C., Wilhelm, Joshua J., Bellin, Melena D., Nylander, Vibe, Gloyn, Anna L., McCarthy, Mark I., Kibbey, Richard G., Krishnaswamy, Smita, Wolpin, Brian M., Jacks, Tyler, Fuchs, Charles S., Muzumdar, Mandar Deepak

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Divergent expression of bacterial wall sensing Toll-like receptors 2 and 4 in colorectal cancer von Paarnio, Karoliina, Väyrynen, Sara, Klintrup, Kai, Ohtonen, Pasi, Mäkinen, Markus J, Mäkelä, Jyrki, Karttunen, Tuomo J

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Micropapillary Structures in Colorectal Cancer: An Anoikis-resistant Subpopulation von Patankar, Madhura, Väyrynen, Sara, Tuomisto, Anne, Mäkinen, Markus, Eskelinen, Sinikka, Karttunen, Tuomo J

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Preoperative anemia in colorectal cancer: relationships with tumor characteristics, systemic inflammation, and survival von Väyrynen, Juha P., Tuomisto, Anne, Väyrynen, Sara A., Klintrup, Kai, Karhu, Toni, Mäkelä, Jyrki, Herzig, Karl-Heinz, Karttunen, Tuomo J., Mäkinen, Markus J.

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Prognostic significance of spatial and density analysis of T lymphocytes in colorectal cancer von Elomaa, Hanna, Ahtiainen, Maarit, Väyrynen, Sara A., Ogino, Shuji, Nowak, Jonathan A., Friman, Marjukka, Helminen, Olli, Wirta, Erkki-Ville, Seppälä, Toni T., Böhm, Jan, Mäkinen, Markus J., Mecklin, Jukka-Pekka, Kuopio, Teijo, Väyrynen, Juha P.

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Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer von Dias Costa, Andressa, Väyrynen, Sara A, Chawla, Akhil, Zhang, Jinming, Väyrynen, Juha P, Lau, Mai Chan, Williams, Hannah L, Yuan, Chen, Morales-Oyarvide, Vicente, Elganainy, Dalia, Singh, Harshabad, Cleary, James M, Perez, Kimberly, Ng, Kimmie, Freed-Pastor, William, Mancias, Joseph D, Dougan, Stephanie K, Wang, Jiping, Rubinson, Douglas A, Dunne, Richard F, Kozak, Margaret M, Brais, Lauren, Reilly, Emma, Clancy, Thomas, Linehan, David C, Chang, Daniel T, Hezel, Aram F, Koong, Albert C, Aguirre, Andrew J, Wolpin, Brian M, Nowak, Jonathan A

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Composition, Spatial Characteristics, and Prognostic Significance of Myeloid Cell Infiltration in Pancreatic Cancer von Väyrynen, Sara A, Zhang, Jinming, Yuan, Chen, Väyrynen, Juha P, Dias Costa, Andressa, Williams, Hannah, Morales-Oyarvide, Vicente, Lau, Mai Chan, Rubinson, Douglas A, Dunne, Richard F, Kozak, Margaret M, Wang, Wenjia, Agostini-Vulaj, Diana, Drage, Michael G, Brais, Lauren, Reilly, Emma, Rahma, Osama, Clancy, Thomas, Wang, Jiping, Linehan, David C, Aguirre, Andrew J, Fuchs, Charles S, Coussens, Lisa M, Chang, Daniel T, Koong, Albert C, Hezel, Aram F, Ogino, Shuji, Nowak, Jonathan A, Wolpin, Brian M

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Smoking and Incidence of Colorectal Cancer Subclassified by Tumor-Associated Macrophage Infiltrates von Ugai, Tomotaka, Väyrynen, Juha P, Haruki, Koichiro, Akimoto, Naohiko, Lau, Mai Chan, Zhong, Rong, Kishikawa, Junko, Väyrynen, Sara A, Zhao, Melissa, Fujiyoshi, Kenji, Dias Costa, Andressa, Borowsky, Jennifer, Arima, Kota, Guerriero, Jennifer L, Fuchs, Charles S, Zhang, Xuehong, Song, Mingyang, Wang, Molin, Giannakis, Marios, Meyerhardt, Jeffrey A, Nowak, Jonathan A, Ogino, Shuji

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Platelet count, aspirin use, and characteristics of host inflammatory responses in colorectal cancer von Väyrynen, Juha P, Väyrynen, Sara A, Sirniö, Päivi, Minkkinen, Ilkka, Klintrup, Kai, Karhu, Toni, Mäkelä, Jyrki, Herzig, Karl-Heinz, Karttunen, Tuomo J, Tuomisto, Anne, Mäkinen, Markus J

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The Prognostic Role of Macrophage Polarization in the Colorectal Cancer Microenvironment von Väyrynen, Juha P, Haruki, Koichiro, Lau, Mai Chan, Väyrynen, Sara A, Zhong, Rong, Dias Costa, Andressa, Borowsky, Jennifer, Zhao, Melissa, Fujiyoshi, Kenji, Arima, Kota, Twombly, Tyler S, Kishikawa, Junko, Gu, Simeng, Aminmozaffari, Saina, Shi, Shanshan, Baba, Yoshifumi, Akimoto, Naohiko, Ugai, Tomotaka, Da Silva, Annacarolina, Guerriero, Jennifer L, Song, Mingyang, Wu, Kana, Chan, Andrew T, Nishihara, Reiko, Fuchs, Charles S, Meyerhardt, Jeffrey A, Giannakis, Marios, Ogino, Shuji, Nowak, Jonathan A

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Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer von Byrne, Katelyn T, Betts, Courtney B, Mick, Rosemarie, Sivagnanam, Shamilene, Bajor, David L, Laheru, Daniel A, Chiorean, E Gabriela, O'Hara, Mark H, Liudahl, Shannon M, Newcomb, Craig, Alanio, Cécile, Ferreira, Ana P, Park, Byung S, Ohtani, Takuya, Huffman, Austin P, Väyrynen, Sara A, Dias Costa, Andressa, Kaiser, Judith C, Lacroix, Andreanne M, Redlinger, Colleen, Stern, Martin, Nowak, Jonathan A, Wherry, E John, Cheever, Martin A, Wolpin, Brian M, Furth, Emma E, Jaffee, Elizabeth M, Coussens, Lisa M, Vonderheide, Robert H

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Clinical impact and network of determinants of tumour necrosis in colorectal cancer von Väyrynen, Sara A, Väyrynen, Juha P, Klintrup, Kai, Mäkelä, Jyrki, Karttunen, Tuomo J, Tuomisto, Anne, Mäkinen, Markus J

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Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer von Elomaa, Hanna, Härkönen, Jouni, Väyrynen, Sara A., Ahtiainen, Maarit, Ogino, Shuji, Nowak, Jonathan A., Lau, Mai Chan, Helminen, Olli, Wirta, Erkki-Ville, Seppälä, Toni T., Böhm, Jan, Mecklin, Jukka-Pekka, Kuopio, Teijo, Väyrynen, Juha P.

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Immune cell profiles in the tumor microenvironment of early-onset, intermediate-onset, and later-onset colorectal cancer von Ugai, Tomotaka, Väyrynen, Juha P., Lau, Mai Chan, Borowsky, Jennifer, Akimoto, Naohiko, Väyrynen, Sara A., Zhao, Melissa, Zhong, Rong, Haruki, Koichiro, Dias Costa, Andressa, Fujiyoshi, Kenji, Arima, Kota, Wu, Kana, Chan, Andrew T., Cao, Yin, Song, Mingyang, Fuchs, Charles S., Wang, Molin, Lennerz, Jochen K., Ng, Kimmie, Meyerhardt, Jeffrey A., Giannakis, Marios, Nowak, Jonathan A., Ogino, Shuji

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A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies von Härkönen, Jouni, Pölönen, Petri, Deen, Ashik Jawahar, Selvarajan, Ilakya, Teppo, Hanna-Riikka, Dimova, Elitsa Y., Kietzmann, Thomas, Ahtiainen, Maarit, Väyrynen, Juha P., Väyrynen, Sara A., Elomaa, Hanna, Tynkkynen, Niko, Eklund, Tiia, Kuopio, Teijo, Talvitie, Eva-Maria, Taimen, Pekka, Kallajoki, Markku, Kaikkonen, Minna U., Heinäniemi, Merja, Levonen, Anna-Liisa

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Leukocyte Heterogeneity in Pancreatic Ductal Adenocarcinoma: Phenotypic and Spatial Features Associated with Clinical Outcome von Liudahl, Shannon M, Betts, Courtney B, Sivagnanam, Shamilene, Morales-Oyarvide, Vicente, da Silva, Annacarolina, Yuan, Chen, Hwang, Samuel, Grossblatt-Wait, Alison, Leis, Kenna R, Larson, William, Lavoie, Meghan B, Robinson, Padraic, Dias Costa, Andressa, Väyrynen, Sara A, Clancy, Thomas E, Rubinson, Douglas A, Link, Jason, Keith, Dove, Horton, Wesley, Tempero, Margaret A, Vonderheide, Robert H, Jaffee, Elizabeth M, Sheppard, Brett, Goecks, Jeremy, Sears, Rosalie C, Park, Byung S, Mori, Motomi, Nowak, Jonathan A, Wolpin, Brian M, Coussens, Lisa M

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Multiplexed analysis of macrophage polarisation in pulmonary metastases of microsatellite stable colorectal cancer von Karjula, Topias, Elomaa, Hanna, Väyrynen, Sara A., Kuopio, Teijo, Ahtiainen, Maarit, Mustonen, Olli, Puro, Iiris, Niskakangas, Anne, Mecklin, Jukka-Pekka, Böhm, Jan, Wirta, Erkki-Ville, Seppälä, Toni T., Sihvo, Eero, Yannopoulos, Fredrik, Helminen, Olli, Väyrynen, Juha P.

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Prognostic Significance of Immune Cell Populations Identified by Machine Learning in Colorectal Cancer Using Routine Hematoxylin and Eosin-Stained Sections von Väyrynen, Juha P, Lau, Mai Chan, Haruki, Koichiro, Väyrynen, Sara A, Dias Costa, Andressa, Borowsky, Jennifer, Zhao, Melissa, Fujiyoshi, Kenji, Arima, Kota, Twombly, Tyler S, Kishikawa, Junko, Gu, Simeng, Aminmozaffari, Saina, Shi, Shanshan, Baba, Yoshifumi, Akimoto, Naohiko, Ugai, Tomotaka, Da Silva, Annacarolina, Song, Mingyang, Wu, Kana, Chan, Andrew T, Nishihara, Reiko, Fuchs, Charles S, Meyerhardt, Jeffrey A, Giannakis, Marios, Ogino, Shuji, Nowak, Jonathan A

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