First-in-Human Intravenous Seprehvir in Young Cancer Patients: A Phase 1 Clinical Trial von Streby, Keri A., Currier, Mark A., Triplet, Melinda, Ott, Kristy, Dishman, Devon J., Vaughan, Michele R., Ranalli, Mark A., Setty, Bhuvana, Skeens, Micah A., Whiteside, Stacy, Yeager, Nicholas D., Haworth, Kellie B., Simpson, Kathleen, Conner, Joe, Cripe, Timothy P.

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Intratumoral Injection of HSV1716, an Oncolytic Herpes Virus, Is Safe and Shows Evidence of Immune Response and Viral Replication in Young Cancer Patients von Streby, Keri A, Geller, James I, Currier, Mark A, Warren, Patrick S, Racadio, John M, Towbin, Alexander J, Vaughan, Michele R, Triplet, Melinda, Ott-Napier, Kristy, Dishman, Devon J, Backus, Lori R, Stockman, Beth, Brunner, Marianne, Simpson, Kathleen, Spavin, Robert, Conner, Joe, Cripe, Timothy P

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Changes in the Geographic Patterns of Heart Disease Mortality in the United States: 1973 to 2010 von Casper, Michele, Kramer, Michael R, Quick, Harrison, Schieb, Linda J, Vaughan, Adam S, Greer, Sophia

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Evaluation of Cerebrospinal Fluid α-Synuclein Seed Amplification Assay in Progressive Supranuclear Palsy and Corticobasal Syndrome von Vaughan, David P, Fumi, Riona, Theilmann Jensen, Marte, Hodgson, Megan, Georgiades, Tatiana, Wu, Lesley, Lux, Danielle, Obrocki, Ruth, Lamoureux, Jennifer, Ansorge, Olaf, Allinson, Kieren S J, Warner, Thomas T, Jaunmuktane, Zane, Misbahuddin, Anjum, Leigh, P Nigel, Ghosh, Boyd C P, Bhatia, Kailash P, Church, Alistair, Kobylecki, Christopher, Hu, Michele T M, Rowe, James B, Blauwendraat, Cornelis, Morris, Huw R, Jabbari, Edwin

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Non-inferiority of cleavage-stage versus blastocyst-stage embryo transfer in poor prognosis IVF patients (PRECiSE trial): study protocol for a randomized controlled trial von Neuhausser, Werner M., Vaughan, Denis A., Sakkas, Denny, Hacker, Michele R., Toth, Tom, Penzias, Alan

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Widespread recent increases in county-level heart disease mortality across age groups von Vaughan, Adam S., Ritchey, Matthew D., Hannan, Judy, Kramer, Michael R., Casper, Michele

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Multiple cryopreservation–warming cycles, coupled with blastocyst biopsy, negatively affect IVF outcomes von Aluko, Ashley, Vaughan, Denis A., Modest, Anna M., Penzias, Alan S., Hacker, Michele R., Thornton, Kim, Sakkas, Denny

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Blasts from the past: is morphology useful in PGT-A tested and untested frozen embryo transfers? von Shear, Matthew A., Vaughan, Denis A., Modest, Anna M., Seidler, Emily A., Leung, Angela Q., Hacker, Michele R., Sakkas, Denny, Penzias, Alan S.

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Biological insights from 108 schizophrenia-associated genetic loci von Neale, Benjamin M, Pers, Tune H, Agartz, Ingrid, Agerbo, Esben, Amin, Farooq, Bergen, Sarah E, Bigdeli, Tim B, Buckner, Randy L, Cai, Guiqing, Catts, Stanley V, Chan, Raymond C. K, Chen, Eric Y. H, Cheng, Wei, Cheung, Eric F. C, Ann Chong, Siow, Robert Cloninger, C, Cohen, Nadine, Crowley, James J, Davidson, Michael, Davis, Kenneth L, Del Favero, Jurgen, Demontis, Ditte, Dinan, Timothy, Djurovic, Srdjan, Drapeau, Elodie, Eriksson, Johan, Escott-Price, Valentina, Friedl, Marion, Fromer, Menachem, Genovese, Giulio, Georgieva, Lyudmila, Giusti-Rodriguez, Paola, Gopal, Srihari, Gratten, Jacob, Hammer, Christian, Hofman, Andrea, Hougaard, David M, Julia, Antonio, Klovins, Janis, Ausrele Kucinskiene, Zita, Hong Lee, S, Lerer, Bernard, Limborska, Svetlana, Lubinski, Jan, Macek Jr, Milan, Magnusson, Patrik K. E, Mattheisen, Manuel, McDonald, Colm, Michie, Patricia T, Milanova, Vihra, Mokrab, Younes, Muller-Myhsok, Bertram, Nenadic, Igor, Nordin, Annelie, Van Os, Jim, Endophenotypes International Consortium, Psychosis, Parkhomenko, Elena, Pejovic-Milovancevic, Milica, Pimm, Jonathan, Price, Alkes, Purcell, Shaun M, Quested, Digby, Rasmussen, Henrik B, Roffman, Joshua L, Schubert, Christian R, Schwab, Sibylle G, Scott, Rodney J, Seidman, Larry J, Silverman, Jeremy M, Smoller, Jordan W, Steinberg, Stacy, Strengman, Eric, Strohmaier, Jana, Svrakic, Dragan M, Soderman, Erik, Thirumalai, Srinivas, Toncheva, Draga, Tosato, Sarah, Veijola, Juha, Walsh, Dermot, Weiser, Mark, Wolen, Aaron R, Zheng, Xuebin, Wray, Naomi R, Visscher, Peter M, Trust Case-Control Consortium, Wellcome, Andreassen, Ole A, Blackwood, Douglas H. R, Esko, Tonu, Gill, Michael, Jablensky, Assen V, McCarroll, Steven A, Mowry, Bryan J, Owen, Michael J, Pato, Carlos N, Posthuma, Danielle, Rujescu, Dan, Sham, Pak C, Sklar, Pamela, St Clair, David

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Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26... von Gray, Richard, Liu, Zulian, Peto, Richard, Davies, Lucy, McGale, Paul, Pan, Hongchao, Taylor, Carolyn, Barlow, William, Bliss, Judith, Bruzzi, Paolo, Cameron, David, Fountzilas, George, Loibl, Sibylle, Martin, Miguel, Möbus, Volker, Nekljudova, Valentina, De Placido, Sabino, Untch, Michael, Norton, Larry, Burrett, Julie, Evans, Vaughan, Hills, Robert, James, Sam, Mannu, Gurdeep, Morris, Philip, Wang, Yaochen, Wang, Zhe, Gnant, Michael, Di Leo, Angelo, Dolci, Stella, Larsimont, Denis, Nogaret, Jean Marie, Piccart, Martine, Linn, Sabine, Peer, Petronella, Tjan-Heijnen, Vivianne, Vliek, Sonja, Slamon, Dennis, Bramwell, Vivien H, Chen, Bingshu, Chia, Stephen, Gelmon, Karen, Goss, Paul, Parulekar, Wendy, Pater, Joseph, Rakovitch, Eileen, Shepherd, Lois, Berry, Don, Broadwater, Gloria, Shan, Yi, Xu, Binghe, Zhao, Dong-Bing, Bartelink, Harry, Cufer, Tanja, Poortmans, Philip, Rutgers, Emiel, van de Velde, Cornelis, Carrasco, Eva, Costa, Serban, Gerber, Bernd, Jackisch, Christian, von Minckwitz, Gunter, Giuliano, Mario, De Laurentiis, Michele, Bamia, Christina, Mavroudis, Dimitris, A'Hern, Roger, Sadoon, Mohammad, Costantino, Joe, Dignam, James, Fisher, Bernard, Mamounas, Eleftherios P, Paik, Soon, Redmond, Carol, Wickerham, D Lawrence, Venturini, Marco, Pastorino, Simona, Sertoli, Mario Roberto, Albain, Kathy, Arriagada, Rodrigo, Bergsten Nordström, Elizabeth, Boccardo, Francesco, Coleman, Robert, Correa, Candace, Dowsett, Mitch, Ewertz, Marianne, Goldhirsch, Aron, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Mukai, Hirofumi, Ohashi, Yasuo, Pierce, Lori, Raina, Vinod, Ravdin, Peter, Rea, Daniel, Sparano, Joseph, Tutt, Andrew, Viale, Giuseppe, Zambetti, Milvia

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Before the here and now: What we can learn from variation in spatiotemporal patterns of changing heart disease mortality by age group, time period, and birth cohort von Vaughan, Adam S., Schieb, Linda, Quick, Harrison, Kramer, Michael R., Casper, Michele

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Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes von Ruderfer, Douglas M., Boocock, James, Stahl, Eli A., Charney, Alexander W., Ori, Anil P.S., Alliey-Rodriguez, Ney, Anjorin, Adebayo, Badner, Judith A., Band, Gavin, Bruggeman, Richard, Buccola, Nancy G., Bumpstead, Suzannah J., Casas, Juan P., Chan, Raymond C.K., Chen, Ronald Y.L., Collier, David A., Cormican, Paul, Craddock, Nicholas, Crowley, James J., Curtis, David, Dannlowski, Udo, Davidson, Michael, Demontis, Ditte, Dronov, Serge, Elvsashagen, Torbjorn, Etain, Bruno, Fan, Chun Chieh, Forty, Liz, Fraser, Christine, Garnham, Julie, Gill, Michael, Gillman, Matthew, Gratten, Jacob, Gwilliam, Rhian, Hammer, Christian, Hansen, Thomas, Henskens, Frans A., Jamain, Stephane, Jankowski, Janusz, Joa, Inge, Julia, Antonio, Kandaswamy, Radhika, Kavanagh, David, Keller, Matthew C., Khrunin, Andrey, Lee, Phil H., Legge, Sophie E., Lencz, Todd, Levinson, Douglas F., Levy, Shawn E., Li, Tao, Lin, Kuang, Macek, Milan, McCarley, Robert W., McGuffin, Peter, McInnis, Melvin G., Meijer, Carin J., Melegh, Bela, Mesholam-Gately, Raquelle I., Myin-Germeys, Inez, Nicodemus, Kristin K., Nimgaonkar, Vishwajit, Nordin, Annelie, Nöthen, Markus M., Van Os, Jim, Owen, Michael J., Palmer, Colin N.A., Palotie, Aarno, Papadimitriou, George N., Pato, Michele T., Perlis, Roy H., Petryshen, Tracey L., Plomin, Robert, Potash, James B., Powell, John, Ramos-Quiroga, Josep Antoni, Rautanen, Anna, Reichenberg, Abraham, Ribases, Marta, Rice, John P., Richards, Alexander L., Ricketts, Michelle, Sanchez-Mora, Cristina, Sanders, Alan R., Schall, Ulrich, Serretti, Alessandro, Sham, Pak C., Straub, Richard E., Strauss, John S., Szatkiewicz, Jin P., Thompson, Robert C., Thorgeirsson, Thorgeir E., Treutlein, Jens, Vedder, Helmut, Wang, Qiang, Wu, Jing Qin, Sullivan, Patrick F., Wray, Naomi R., Sklar, Pamela, Kendler, Kenneth S.

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Genome-wide association study identifies five new schizophrenia loci von Ripke, Stephan, Sanders, Alan R, Kendler, Kenneth S, Levinson, Douglas F, Sklar, Pamela, Holmans, Peter A, Lin, Dan-Yu, Duan, Jubao, Ophoff, Roel A, Andreassen, Ole A, Scolnick, Edward, Cichon, Sven, St Clair, David, Corvin, Aiden, Gurling, Hugh, Werge, Thomas, Rujescu, Dan, Blackwood, Douglas H R, Pato, Carlos N, Malhotra, Anil K, Purcell, Shaun, Dudbridge, Frank, Neale, Benjamin M, Rossin, Lizzy, Visscher, Peter M, Posthuma, Danielle, Ruderfer, Douglas M, Fanous, Ayman, Stefansson, Hreinn, Steinberg, Stacy, Mowry, Bryan J, Golimbet, Vera, De Hert, Marc, Jonsson, Erik G, Bitter, Istvan, Pietilaeinen, Olli P H, Collier, David A, Tosato, Sarah, Agartz, Ingrid, Albus, Margot, Alexander, Madeline, Amdur, Richard L, Amin, Farooq, Bass, Nicholas, Bergen, Sarah E, Black, Donald W, Boerglum, Anders D, Brown, Matthew A, Bruggeman, Richard, Buccola, Nancy G

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Disparities in Temporal and Geographic Patterns of Declining Heart Disease Mortality by Race and Sex in the United States, 1973-2010 von Vaughan, Adam S, Quick, Harrison, Pathak, Elizabeth B, Kramer, Michael R, Casper, Michele

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Complement genes contribute sex-biased vulnerability in diverse disorders von Kamitaki, Nolan, Sekar, Aswin, Handsaker, Robert E., de Rivera, Heather, Tooley, Katherine, Morris, David L., Taylor, Kimberly E., Whelan, Christopher W., Tombleson, Philip, Loohuis, Loes M. Olde, Boehnke, Michael, Kimberly, Robert P., Kaufman, Kenneth M., Harley, John B., Langefeld, Carl D., Seidman, Christine E., Pato, Michele T., Pato, Carlos N., Ophoff, Roel A., Graham, Robert R., Criswell, Lindsey A., Vyse, Timothy J., McCarroll, Steven A.

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Telemedicine for reproductive medicine: pandemic and beyond von Vaughan, Denis A, Yin, Sophia H, Shah, Jaimin S, Gompers, Annika, Hacker, Michele R, Sakkas, Denny, Domar, Alice, Toth, Thomas L

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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk von Huckins, Laura M., Dobbyn, Amanda, Ruderfer, Douglas M., Hoffman, Gabriel, Wang, Weiqing, Pardiñas, Antonio F., Rajagopal, Veera M., Als, Thomas D., T. Nguyen, Hoang, Girdhar, Kiran, Boocock, James, Roussos, Panos, Fromer, Menachem, Kramer, Robin, Domenici, Enrico, Gamazon, Eric R., Purcell, Shaun, Demontis, Ditte, Børglum, Anders D., Walters, James T. R., O’Donovan, Michael C., Sullivan, Patrick, Owen, Michael J., Devlin, Bernie, Sieberts, Solveig K., Cox, Nancy J., Im, Hae Kyung, Sklar, Pamela, Stahl, Eli A.

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Acceptance of genetic editing and of whole genome sequencing of human embryos by patients with infertility before and after the onset of the COVID-19 pandemic von Neuhausser, Werner M., Fouks, Yuval, Lee, Si Won, Macharia, Annliz, Hyun, Insoo, Adashi, Eli Y., Penzias, Alan S., Hacker, Michele R., Sakkas, Denny, Vaughan, Denis

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A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts von Ni, Guiyan, Wang, Ying, Ge, Tian, Smoller, Jordan W., Ripke, Stephan, Farh, Kai-How, Holmans, Peter A., Agartz, Ingrid, Belliveau, Richard A., Bigdeli, Tim B., Black, Donald W., Buckner, Randy L., Cheng, Wei, Degenhardt, Franziska, Dudbridge, Frank, Eichhammer, Peter, Farrell, Martilias S., Frank, Josef, Freedman, Robert, Friedl, Marion, Giegling, Ina, Giusti-Rodríguez, Paola, Gratten, Jacob, Hartmann, Annette M., Hollegaard, Mads V., Kahn, René S., Karachanak-Yankova, Sena, Kavanagh, David, Keller, Matthew C., Kennedy, James L., Knowles, James A., Kucinskiene, Zita Ausrele, Li, Tao, Loughland, Carmel M., Lubinski, Jan, Maier, Wolfgang, Mallet, Jacques, Michie, Patricia T., Myin-Germeys, Inez, Nertney, Deborah A., Nicodemus, Kristin K., Nikitina-Zake, Liene, O’Callaghan, Eadbhard, O’Dushlaine, Colm, Pejovic-Milovancevic, Milica, Pocklington, Andrew J., Powell, John, Pulver, Ann E., Ruderfer, Douglas M., Salomaa, Veikko, Shi, Jianxin, Sim, Kang, Slominsky, Petr, Spencer, Chris C.A., Stahl, Eli A., Steinberg, Stacy, Stogmann, Elisabeth, Suvisaari, Jaana, Williams, Nigel M., Witt, Stephanie H., Wormley, Brandon K., Blackwood, Douglas H.R., Bramon, Elvira, Buxbaum, Joseph D., Esko, Tõnu, Gurling, Hugh, Moran, Jennifer L., Mowry, Bryan J., Owen, Michael J., Petryshen, Tracey L., Weinberger, Daniel R., Byrne, Enda M., Abdellaoui, Abdel, Andlauer, Till F.M., Castelao, Enrique, Derks, Eske M., Foo, Jerome C., Forstner, Andreas J., Hall, Lynsey S., Homuth, Georg, Jansen, Rick, Jones, Ian, Jones, Lisa A., Kretzschmar, Warren W., McGuffin, Peter, Mihailov, Evelin, Mostafavi, Sara, Nivard, Michel G., O’Reilly, Paul F., Quiroz, Jorge A., Smith, Daniel J., Thompson, Wesley, Treutlein, Jens, Umbricht, Daniel, Wu, Yang, Zhang, Futao, Grabe, Hans J., Hayward, Caroline, Lewis, Glyn, Wray, Naomi R.

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Comparing methods of measuring geographic patterns in temporal trends: an application to county-level heart disease mortality in the United States, 1973 to 2010 von Vaughan, Adam S., MPH, MS, Kramer, Michael R., PhD, Waller, Lance A., PhD, Schieb, Linda J., MSPH, Greer, Sophia, MPH, Casper, Michele, PhD

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