Mouse model hints at pharmacogenomic strategies for stroke treatment in patients possessing a risk variant von Vaughan, Douglas E

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Molecular and physiological manifestations and measurement of aging in humans von Khan, Sadiya S., Singer, Benjamin D., Vaughan, Douglas E.

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PAI-1 in tissue fibrosis von Ghosh, Asish K., Vaughan, Douglas E.

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Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence von Vaughan, Douglas E, Rai, Rahul, Khan, Sadiya S, Eren, Mesut, Ghosh, Asish K

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MiR-125b Is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis von Nagpal, Varun, Rai, Rahul, Place, Aaron T, Murphy, Sheila B, Verma, Suresh K, Ghosh, Asish K, Vaughan, Douglas E

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Molecular basis of organ fibrosis: Potential therapeutic approaches von Ghosh, Asish K, Quaggin, Susan E, Vaughan, Douglas E

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Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction von Wan, Elaine, Yeap, Xin Yi, Dehn, Shirley, Terry, Rachael, Novak, Margaret, Zhang, Shuang, Iwata, Shinichi, Han, Xiaoqiang, Homma, Shunichi, Drosatos, Konstantinos, Lomasney, Jon, Engman, David M., Miller, Stephen D., Vaughan, Douglas E., Morrow, John P., Kishore, Raj, Thorp, Edward B.

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Acetyltransferase p300 inhibitor reverses hypertension‐induced cardiac fibrosis von Rai, Rahul, Sun, Tianjiao, Ramirez, Veronica, Lux, Elizabeth, Eren, Mesut, Vaughan, Douglas E., Ghosh, Asish K.

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Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): Differential expression of microRNAs during EndMT von Ghosh, Asish K., Nagpal, Varun, Covington, Joseph W., Michaels, Marissa A., Vaughan, Douglas E.

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Plasminogen Activator Inhibitor-1 Antagonist TM5484 Attenuates Demyelination and Axonal Degeneration in a Mice Model of Multiple Sclerosis von Pelisch, Nicolas, Dan, Takashi, Ichimura, Atsuhiko, Sekiguchi, Hiroki, Vaughan, Douglas E, van Ypersele de Strihou, Charles, Miyata, Toshio

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Glycine supplementation extends lifespan of male and female mice von Miller, Richard A., Harrison, David E., Astle, C. Michael, Bogue, Molly A., Brind, Joel, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin, Ladiges, Warren, Leeuwenburgh, Christiaan, Macchiarini, Francesca, Nelson, James, Ryazanov, Alexey G., Snyder, Jessica, Stearns, Timothy M., Vaughan, Douglas E., Strong, Randy

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PAI-1–regulated extracellular proteolysis governs senescence and survival in Klotho mice von Eren, Mesut, Boe, Amanda E., Murphy, Sheila B., Place, Aaron T., Nagpal, Varun, Morales-Nebreda, Luisa, Urich, Daniela, Quaggin, Susan E., Budinger, G. R. Scott, Mutlu, Gökhan M., Miyata, Toshio, Vaughan, Douglas E.

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Role of PAI-1 in hepatic steatosis and dyslipidemia von Levine, Joshua A., Oleaga, Carlota, Eren, Mesut, Amaral, Ansel P., Shang, Meng, Lux, Elizabeth, Khan, Sadiya S., Shah, Sanjiv J., Omura, Yasuhiro, Pamir, Nathalie, Hay, Joshua, Barish, Grant, Miyata, Toshio, Tavori, Hagai, Fazio, Sergio, Vaughan, Douglas E.

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Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells von Yahata, Takashi, Ibrahim, Abd Aziz, Hirano, Ken-ichi, Muguruma, Yukari, Naka, Kazuhito, Hozumi, Katsuto, Vaughan, Douglas E., Miyata, Toshio, Ando, Kiyoshi

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Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484 von Sillen, Machteld, Miyata, Toshio, Vaughan, Douglas E., Strelkov, Sergei V., Declerck, Paul J.

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DNA Damage: A Main Determinant of Vascular Aging von Bautista-Niño, Paula K, Portilla-Fernandez, Eliana, Vaughan, Douglas E, Danser, A H Jan, Roks, Anton J M

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Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis von Ghosh, Asish K, Murphy, Sheila B, Kishore, Raj, Vaughan, Douglas E

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A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis von Rai, Rahul, Verma, Suresh K., Kim, David, Ramirez, Veronica, Lux, Elizabeth, Li, Chengjin, Sahoo, Susmita, Wilsbacher, Lisa D., Vaughan, Douglas E., Quaggin, Susan E., Ghosh, Asish K.

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Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan von Rai, Rahul, Ghosh, Asish K., Eren, Mesut, Mackie, Alexander R., Levine, Daniel C., Kim, So-Youn, Cedernaes, Jonathan, Ramirez, Veronica, Procissi, Daniele, Smith, Layton H., Woodruff, Teresa K., Bass, Joseph, Vaughan, Douglas E.

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Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production von Siddiquee, Khandaker, Hampton, Jessica, Khan, Susan, Zadory, Dan, Gleaves, Linda, Vaughan, Douglas E, Smith, Layton H

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