Parkinson's disease outside the brain: targeting the autonomic nervous system von Sharabi, Yehonatan, Vatine, Gad D, Ashkenazi, Avraham

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Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications von Vatine, Gad D., Barrile, Riccardo, Workman, Michael J., Sances, Samuel, Barriga, Bianca K., Rahnama, Matthew, Barthakur, Sonalee, Kasendra, Magdalena, Lucchesi, Carolina, Kerns, Jordan, Wen, Norman, Spivia, Weston R., Chen, Zhaohui, Van Eyk, Jennifer, Svendsen, Clive N.

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An isogenic blood–brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells von Canfield, Scott G., Stebbins, Matthew J., Morales, Bethsymarie Soto, Asai, Shusaku W., Vatine, Gad D., Svendsen, Clive N., Palecek, Sean P., Shusta, Eric V.

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Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier von Vatine, Gad D., Al-Ahmad, Abraham, Barriga, Bianca K., Svendsen, Soshana, Salim, Ariel, Garcia, Leslie, Garcia, Veronica J., Ho, Ritchie, Yucer, Nur, Qian, Tongcheng, Lim, Ryan G., Wu, Jie, Thompson, Leslie M., Spivia, Weston R., Chen, Zhaohui, Van Eyk, Jennifer, Palecek, Sean P., Refetoff, Samuel, Shusta, Eric V., Svendsen, Clive N.

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Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits von Lim, Ryan G., Quan, Chris, Reyes-Ortiz, Andrea M., Lutz, Sarah E., Kedaigle, Amanda J., Gipson, Theresa A., Wu, Jie, Vatine, Gad D., Stocksdale, Jennifer, Casale, Malcolm S., Svendsen, Clive N., Fraenkel, Ernest, Housman, David E., Agalliu, Dritan, Thompson, Leslie M.

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PLEKHM2 Loss of Function Impairs the Activity of iPSC-Derived Neurons via Regulation of Autophagic Flux von Ben-Zvi, Hadas, Rabinski, Tatiana, Ofir, Rivka, Cohen, Smadar, Vatine, Gad D

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Impedance Characteristics of Microfluidic Channels and Integrated Coplanar Parallel Electrodes as Design Parameters for Whole-Channel Analysis in Organ-on-Chip Micro-Systems von Rapier, Crystal E, Jagadeesan, Srikanth, Vatine, Gad D, Ben-Yoav, Hadar

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The light-induced transcriptome of the zebrafish pineal gland reveals complex regulation of the circadian clockwork by light von Ben-Moshe, Zohar, Alon, Shahar, Mracek, Philipp, Faigenbloom, Lior, Tovin, Adi, Vatine, Gad D, Eisenberg, Eli, Foulkes, Nicholas S, Gothilf, Yoav

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Generation of iPSC lines from two (BGUi002-A and BGUi003-A) homozygous p450 oxidoreductase-deficient patients and from one (BGUi001-A) heterozygous healthy family relative von Zlotnik, Dor, Rabinski, Tatiana, Ofir, Rivka, Hershkovitz, Eli, Vatine, Gad D.

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Induced pluripotent stem cell (iPSC) lines from two individuals carrying a homozygous (BGUi007-A) and a heterozygous (BGUi006-A) mutation in ELP1 for in vitro modeling of familial... von Dor, Lior, Rabinski, Tatiana, Zlotnik, Dor, Shilian, Michal, Weil, Miguel, Vatine, Gad D.

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Generation and characterization of iPSC lines (BGUi004-A, BGUi005-A) from two identical twins with polyalanine expansion in the paired-like homeobox 2B (PHOX2B) gene von Falik, Daniel, Rabinski, Tatiana, Zlotnik, Dor, Eshel, Reut, Zorsky, Meshi, Garin-Shkolnik, Tali, Ofir, Rivka, Adato, Avital, Ashkenazi, Avraham, Vatine, Gad D.

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SnapShot: Autonomic nervous system disorders von Sharabi, Yehonatan, Vatine, Gad D., Ashkenazi, Avraham

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Reprogramming of two induced pluripotent stem cell lines from a heterozygous GRIN2D developmental and epileptic encephalopathy (DEE) patient (BGUi011-A) and from a healthy family r... von Rabinski, Tatiana, Sagiv, Sivan T., Hausman-Kedem, Moran, Fattal-Valevski, Aviva, Rubinstein, Moran, Avraham, Karen B., Vatine, Gad D.

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Sodium Phenylbutyrate Rescues Thyroid Hormone Transport in Brain Endothelial-Like Cells von Braun, Doreen, Bohleber, Simon, Vatine, Gad D, Svendsen, Clive N, Schweizer, Ulrich

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Chronic and acute exposure to rotenone reveals distinct Parkinson's disease-related phenotypes in human iPSC-derived peripheral neurons von Saleh, Mahmood Ali, Amer-Sarsour, Fatima, Berant, Asaf, Pasmanik-Chor, Metsada, Kobo, Hila, Sharabi, Yehonatan, Vatine, Gad D., Ashkenazi, Avraham

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Introducing ADNP and SIRT1 as new partners regulating microtubules and histone methylation von Hadar, Adva, Kapitansky, Oxana, Ganaiem, Maram, Sragovich, Shlomo, Lobyntseva, Alexandra, Giladi, Eliezer, Yeheskel, Adva, Avitan, Aliza, Vatine, Gad D., Gurwitz, David, Ivashko-Pachima, Yanina, Gozes, Illana

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Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination von Amer-Sarsour, Fatima, Falik, Daniel, Berdichevsky, Yevgeny, Kordonsky, Alina, Eid, Sharbel, Rabinski, Tatiana, Ishtayeh, Hasan, Cohen-Adiv, Stav, Braverman, Itzhak, Blumen, Sergiu C, Laviv, Tal, Prag, Gali, Vatine, Gad D, Ashkenazi, Avraham

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Oligodendrocyte progenitor cell maturation is dependent on dual function of MCT8 in the transport of thyroid hormone across brain barriers and the plasma membrane von Vatine, Gad D., Shelest, Oksana, Barriga, Bianca K., Ofan, Raz, Rabinski, Tatyana, Mattis, Virginia B., Heuer, Heike, Svendsen, Clive N.

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AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency von Liao, Xiao-Hui, Avalos, Pablo, Shelest, Oksana, Ofan, Raz, Shilo, Michael, Bresee, Catherine, Likhite, Shibi, Vit, Jean-Philippe, Heuer, Heike, Kaspar, Brian, Meyer, Kathrin, Dumitrescu, Alexandra M, Refetoff, Samuel, Svendsen, Clive N, Vatine, Gad D

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Generation of a Human iPSC-Based Blood-Brain Barrier Chip von Jagadeesan, Srikanth, Workman, Michael J., Herland, Anna, Svendsen, Clive N., Vatine, Gad D.

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