Preclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061 von Burkey, Bryan F, Hoglen, Niel C, Inskeep, Philip, Wyman, Margaret, Hughes, Thomas E, Vath, James E

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MetAP2 inhibitor treatment of high-fat and -fructose-fed dogs: impact on the response to oral glucose ingestion and a hyperinsulinemic hyperglycemic clamp von Moore, Mary Courtney, Coate, Katie C., Scott, Melanie, Kraft, Guillaume, Vath, James E., Hughes, Thomas E., Farmer, Ben, Cherrington, Alan D.

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MetAP2 inhibition reduces food intake and body weight in a ciliopathy mouse model of obesity von Pottorf, Tana S., Fagan, Micaella P., Burkey, Bryan F., Cho, David J., Vath, James E., Tran, Pamela V.

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Human pharmacokinetics and mass balance study of beloranib using LC–MS/MS von Inskeep, Philip, Hsieh, Frank, Liu, Nanjun, Tengstrand, Elizabeth, Ryzhikova, Elena, Vath, James, Malloy, Jaret, Bertelsen-Purika, Sandy, Gartner, Michael

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Physiological mechanisms of sustained fumagillin-induced weight loss von An, Jie, Wang, Liping, Patnode, Michael L, Ridaura, Vanessa K, Haldeman, Jonathan M, Stevens, Robert D, Ilkayeva, Olga, Bain, James R, Muehlbauer, Michael J, Glynn, Erin L, Thomas, Steven, Muoio, Deborah, Summers, Scott A, Vath, James E, Hughes, Thomas E, Gordon, Jeffrey I, Newgard, Christopher B

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Identification of the facile gas-phase cleavage of the Asp-Pro and Asp-Xxx peptide bonds in matrix-assisted laser desorption time-of-flight mass spectrometry von Yu, Wen, Vath, James E, Huberty, Michael C, Martin, Stephen A

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ZGN-1061 Improves Metabolic Parameters and Hepatic Pathology in an Obese Mouse Model of Diet-Induced and Biopsy-Confirmed Nonalcoholic Steatohepatitis von BURKEY, BRYAN F., ILLEMANN, MARTIN, VEIDAL, SANNE, FEIGH, MICHAEL, VATH, JAMES, HUGHES, THOMAS E.

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ZGN-1061, a Novel MetAP2 Inhibitor, and Liraglutide Combine to Improve Glycemic Control and Reduce Body Weight in a Rat Model of Diet-Induced Obesity von BURKEY, BRYAN F., PEDERSEN, PHILIP J., PEDERSEN, TANJA X., FEIGH, MICHAEL, VATH, JAMES, HUGHES, THOMAS E.

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Site-specific carbohydrate identification in recombinant proteins using MALD-TOF MS von Huberty, Michael C, Vath, James E, Yu, Wen, Martin, Stephen A

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Direct Isoform Analysis of High-Mannose-Containing Glycoproteins by On-Line Capillary Electrophoresis Electrospray Mass Spectrometry von Yeung, Bernice, Porter, Thomas J, Vath, James E

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Late-Onset Pharmacological or Dietary Interventions Improve Healthspan and Lifespan in Male and Female Mice von Mitchell, Sarah, MacArthur, Michael, Kane, Alice, Torrence, Margaret, Mehmet, Huseyin, Vath, James, Manning, Brendan, Mitchell, James

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Quantitative Comparison of Global Carbohydrate Structures of Glycoproteins Using LC−MS and In-Source Fragmentation von Mazsaroff, Istvan, Yu, Wen, Kelley, Brian D, Vath, James E

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De novo peptide sequencing via tandem mass spectrometry von Dancík, V, Addona, T A, Clauser, K R, Vath, J E, Pevzner, P A

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Isomeric Differentiation of Asparagine-Linked Oligosaccharides by Matrix-Assisted Laser Desorption–Ionization Postsource Decay Time-of-Flight Mass Spectrometry von Rouse, Jason C., Strang, Anne-Marie, Yu, Wen, Vath, James E.

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COMPOSITIONS AND METHODS FOR TREATMENT OF PRADER-WILLI SYNDROME von VATH, James E, UYSAL, Teoman

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Methods of treating an overweight or obese subject von VATH, JAMES

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METHODS OF TREATING DISORDERS RELATED TO GLYCEMIC CONTROL von VATH, James, BURKEY, Bryan

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Methods of treating liver diseases von Hughes, Thomas, Vath, James

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METHODS OF TREATING AN OVERWEIGHT OR OBESE SUBJECT von Vath, James E

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PHARMACEUTICAL COMPOSITIONS OF METAP-2 INHIBITORS von VATH, James, BURKEY, Bryan

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