The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers von Razavi, Pedram, Chang, Matthew T., Xu, Guotai, Bandlamudi, Chaitanya, Ross, Dara S., Vasan, Neil, Cai, Yanyan, Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Penson, Alexander, Shen, Ronglai, Pareja, Fresia, Kundra, Ritika, Middha, Sumit, Cheng, Michael L., Zehir, Ahmet, Kandoth, Cyriac, Patel, Ruchi, Huberman, Kety, Smyth, Lillian M., Jhaveri, Komal, Modi, Shanu, Traina, Tiffany A., Dang, Chau, Zhang, Wen, Weigelt, Britta, Li, Bob T., Ladanyi, Marc, Hyman, David M., Schultz, Nikolaus, Robson, Mark E., Hudis, Clifford, Brogi, Edi, Viale, Agnes, Norton, Larry, Dickler, Maura N., Berger, Michael F., Iacobuzio-Donahue, Christine A., Chandarlapaty, Sarat, Scaltriti, Maurizio, Reis-Filho, Jorge S., Solit, David B., Taylor, Barry S., Baselga, José

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A RAS Renaissance: Emerging Targeted Therapies for KRAS-Mutated Non-Small Cell Lung Cancer von VASAN, Neil, BOYER, Julie L, HERBST, Roy S

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Phase and context shape the function of composite oncogenic mutations von Gorelick, Alexander N., Sánchez-Rivera, Francisco J., Cai, Yanyan, Bielski, Craig M., Biederstedt, Evan, Jonsson, Philip, Richards, Allison L., Vasan, Neil, Penson, Alexander V., Friedman, Noah D., Ho, Yu-Jui, Baslan, Timour, Bandlamudi, Chaitanya, Scaltriti, Maurizio, Schultz, Nikolaus, Lowe, Scott W., Reznik, Ed, Taylor, Barry S.

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Therapeutic potential of inhibiting the PI3Kγ complex for leukemia von Karvonen, Hanna, Vasan, Neil

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Alterations in PTEN and ESR1 promote clinical resistance to alpelisib plus aromatase inhibitors von Razavi, Pedram, Dickler, Maura N., Shah, Payal D., Toy, Weiyi, Brown, David N., Won, Helen H., Li, Bob T., Shen, Ronglai, Vasan, Neil, Modi, Shanu, Jhaveri, Komal, Caravella, Betty Ann, Patil, Sujata, Selenica, Pier, Zamora, Stephen, Cowan, Aimee M., Comen, Elizabeth, Singh, Andy, Covey, Anne, Berger, Michael F., Hudis, Clifford A., Norton, Larry, Nagy, Rebecca J., Odegaard, Justin I., Lanman, Richard B., Solit, David B., Robson, Mark E., Lacouture, Mario E., Brogi, Edi, Reis-Filho, Jorge S., Moynahan, Mary Ellen, Scaltriti, Maurizio, Chandarlapaty, Sarat

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Epinephrine inhibits PI3Kα via the Hippo kinases von Lin, Ting-Yu, Ramsamooj, Shakti, Perrier, Tiffany, Liberatore, Katarina, Lantier, Louise, Vasan, Neil, Karukurichi, Kannan, Hwang, Seo-Kyoung, Kesicki, Edward A., Kastenhuber, Edward R., Wiederhold, Thorsten, Yaron, Tomer M., Huntsman, Emily M., Zhu, Mengmeng, Ma, Yilun, Paddock, Marcia N., Zhang, Guoan, Hopkins, Benjamin D., McGuinness, Owen, Schwartz, Robert E., Ersoy, Baran A., Cantley, Lewis C., Johnson, Jared L., Goncalves, Marcus D.

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A view on drug resistance in cancer von Vasan, Neil, Baselga, José, Hyman, David M.

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Treating Alpelisib-Induced Hyperglycemia with Very Low Carbohydrate Diets and Sodium-Glucose Co-Transporter 2 Inhibitors: A Case Series von Blow, Tahj, Hyde, Parker N., Falcone, John N., Neinstein, Aaron, Vasan, Neil, Chitkara, Ritika, Hurd, Maurice A., Sardesai, Sagar, Lustberg, Maryam B., Flory, James H., Volek, Jeff S., Goncalves, Marcus D.

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At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy von Vasan, Neil, Cantley, Lewis C.

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Structure of a C-terminal fragment of its Vps53 subunit suggests similarity of Golgi-associated retrograde protein (GARP) complex to a family of tethering complexes von Vasan, Neil, Hutagalung, Alex, Novick, Peter, Reinisch, Karin M., De Camilli, Pietro

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Genomic Characterization of De Novo Metastatic Breast Cancer von Mullangi, Samyukta, Vasan, Neil

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A New Wave of PI3Kα Inhibitors von Kearney, Alison L, Vasan, Neil

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José Baselga (1959–2021) von Castel, Pau, Toska, Eneda, Vasan, Neil, Cocco, Emiliano, Scaltriti, Maurizio

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Jose Baselga (1959-2021) Obituary von Castel, Pau, Toska, Eneda, Vasan, Neil, Cocco, Emiliano, Scaltriti, Maurizio

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An atlas of substrate specificities for the human serine/threonine kinome von Johnson, Jared L., Yaron, Tomer M., Huntsman, Emily M., Kerelsky, Alexander, Song, Junho, Regev, Amit, Lin, Ting-Yu, Liberatore, Katarina, Cizin, Daniel M., Cohen, Benjamin M., Vasan, Neil, Ma, Yilun, Krismer, Konstantin, Robles, Jaylissa Torres, van de Kooij, Bert, van Vlimmeren, Anne E., Andrée-Busch, Nicole, Käufer, Norbert F., Dorovkov, Maxim V., Ryazanov, Alexey G., Takagi, Yuichiro, Kastenhuber, Edward R., Goncalves, Marcus D., Hopkins, Benjamin D., Elemento, Olivier, Taatjes, Dylan J., Maucuer, Alexandre, Yamashita, Akio, Degterev, Alexei, Uduman, Mohamed, Lu, Jingyi, Landry, Sean D., Zhang, Bin, Cossentino, Ian, Linding, Rune, Blenis, John, Hornbeck, Peter V., Turk, Benjamin E., Yaffe, Michael B., Cantley, Lewis C.

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Dietary fructose improves intestinal cell survival and nutrient absorption von Taylor, Samuel R., Ramsamooj, Shakti, Liang, Roger J., Katti, Alyna, Pozovskiy, Rita, Vasan, Neil, Hwang, Seo-Kyoung, Nahiyaan, Navid, Francoeur, Nancy J., Schatoff, Emma M., Johnson, Jared L., Shah, Manish A., Dannenberg, Andrew J., Sebra, Robert P., Dow, Lukas E., Cantley, Lewis C., Rhee, Kyu Y., Goncalves, Marcus D.

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Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors von Vasan, Neil, Razavi, Pedram, Johnson, Jared L, Shao, Hong, Shah, Hardik, Antoine, Alesia, Ladewig, Erik, Gorelick, Alexander, Lin, Ting-Yu, Toska, Eneda, Xu, Guotai, Kazmi, Abiha, Chang, Matthew T, Taylor, Barry S, Dickler, Maura N, Jhaveri, Komal, Chandarlapaty, Sarat, Rabadan, Raul, Reznik, Ed, Smith, Melissa L, Sebra, Robert, Schimmoller, Frauke, Wilson, Timothy R, Friedman, Lori S, Cantley, Lewis C, Scaltriti, Maurizio, Baselga, José

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Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis von Li, Jun, Duran, Mercedes A., Dhanota, Ninjit, Chatila, Walid K., Bettigole, Sarah E., Kwon, John, Sriram, Roshan K., Humphries, Matthew P., Salto-Tellez, Manuel, James, Jacqueline A., Hanna, Matthew G., Melms, Johannes C., Vallabhaneni, Sreeram, Litchfield, Kevin, Usaite, Ieva, Biswas, Dhruva, Bareja, Rohan, Li, Hao Wei, Martin, Maria Laura, Dorsaint, Princesca, Cavallo, Julie-Ann, Li, Peng, Pauli, Chantal, Gottesdiener, Lee, DiPardo, Benjamin J., Hollmann, Travis J., Merghoub, Taha, Wen, Hannah Y., Reis-Filho, Jorge S., Riaz, Nadeem, Su, Shin-San Michael, Kalbasi, Anusha, Vasan, Neil, Powell, Simon N., Wolchok, Jedd D., Elemento, Olivier, Swanton, Charles, Shoushtari, Alexander N., Parkes, Eileen E., Izar, Benjamin, Bakhoum, Samuel F.

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Abstract P3-09-04: Genomic landscape of HER2-negative advanced or metastatic breast cancer with PIK3CA gain-of-function mutations von Xi, Jing, Harnden, Kathleen, Luo, Jingqin, Call, Greg S., Mauer, Elizabeth, Ronski, Karyn, Ma, Cynthia X., Vasan, Neil

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Molecular characteristics of advanced colorectal cancer and multi-hit PIK3CA mutations von Yasin, Faiza, Sokol, Ethan, Vasan, Neil, Pavlick, Dean C, Huang, Richard S P, Pelletier, Maureen, Levy, Mia Alyce, Pusztai, Lajos, Lacy, Jill, Zhang, Janie Yue, Ross, Jeffrey S, Cecchini, Michael

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