Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a) von Koren, Michael J., Moriarty, Patrick Maurice, Baum, Seth J., Neutel, Joel, Hernandez-Illas, Martha, Weintraub, Howard S., Florio, Monica, Kassahun, Helina, Melquist, Stacey, Varrieur, Tracy, Haldar, Saptarsi M., Sohn, Winnie, Wang, Huei, Elliott-Davey, Mary, Rock, Brooke M., Pei, Tao, Homann, Oliver, Hellawell, Jennifer, Watts, Gerald F.

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Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial von de Langen, Adrianus Johannes, Johnson, Melissa L, Mazieres, Julien, Dingemans, Anne-Marie C, Mountzios, Giannis, Pless, Miklos, Wolf, Jürgen, Schuler, Martin, Lena, Hervé, Skoulidis, Ferdinandos, Yoneshima, Yasuto, Kim, Sang-We, Linardou, Helena, Novello, Silvia, van der Wekken, Anthonie J, Chen, Yuanbin, Peters, Solange, Felip, Enriqueta, Solomon, Benjamin J, Ramalingam, Suresh S., Dooms, Christophe, Lindsay, Colin R, Ferreira, Carlos Gil, Blais, Normand, Obiozor, Cynthia C, Wang, Yang, Mehta, Bhakti, Varrieur, Tracy, Ngarmchamnanrith, Gataree, Stollenwerk, Björn, Waterhouse, David, Paz-Ares, Luis

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Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease von O’Donoghue, Michelle L., Rosenson, Robert S., Gencer, Baris, López, J. Antonio G., Lepor, Norman E., Baum, Seth J., Stout, Elmer, Gaudet, Daniel, Knusel, Beat, Kuder, Julia F., Ran, Xinhui, Murphy, Sabina A., Wang, Huei, Wu, You, Kassahun, Helina, Sabatine, Marc S.

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Pharmacokinetics, Pharmacodynamics, and Tolerability of Olpasiran in Healthy Japanese and Non-Japanese Participants: Results from a Phase I, Single-dose, Open-label Study von Sohn, Winnie, Winkle, Peter, Neutel, Joel, Wu, You, Jabari, Freeman, Terrio, Caitlin, Varrieur, Tracy, Wang, Jingying, Hellawell, Jennifer

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Sotorasib with panitumumab in chemotherapy-refractory KRASG12C-mutated colorectal cancer: a phase 1b trial von Kuboki, Yasutoshi, Fakih, Marwan, Strickler, John, Yaeger, Rona, Masuishi, Toshiki, Kim, Edward J., Bestvina, Christine M., Kopetz, Scott, Falchook, Gerald S., Langer, Corey, Krauss, John, Puri, Sonam, Cardona, Panli, Chan, Emily, Varrieur, Tracy, Mukundan, Lata, Anderson, Abraham, Tran, Qui, Hong, David S.

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Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial von Kuboki, Yasutoshi, Fakih, Marwan, Strickler, John, Yaeger, Rona, Masuishi, Toshiki, Kim, Edward J, Bestvina, Christine M, Kopetz, Scott, Falchook, Gerald S, Langer, Corey, Krauss, John, Puri, Sonam, Cardona, Panli, Chan, Emily, Varrieur, Tracy, Mukundan, Lata, Anderson, Abraham, Tran, Qui, Hong, David S

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Sotorasib versus docetaxel for previously treated non-small- cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial von de Langen, Adrianus Johannes, Johnson, Melissa L, Mazieres, Julien, Dingemans, Anne-Marie C, Mountzios, Giannis, Pless, Miklos, Wolf, Jurgen, Schuler, Martin, Lena, Herve, Skoulidis, Ferdinandos, Yoneshima, Yasuto, Kim, Sang-We, Linardou, Helena, Novello, Silvia, van der Wekken, Anthonie J, Chen, Yuanbin, Peters, Solange, Felip, Enriqueta, Solomon, Benjamin J, Ramalingam, Suresh S, Dooms, Christophe, Lindsay, Colin R, Ferreira, Carlos Gil, Blais, Normand, Obiozor, Cynthia C, Wang, Yang, Mehta, Bhakti, Varrieur, Tracy, Ngarmchamnanrith, Gataree, Stollenwerk, Bjorn, Waterhouse, David, Paz-Ares, Luis

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Abstract 13951: Safety, Tolerability and Efficacy of Single-dose Amg 890, a Novel Sirna Targeting Lp(a), in Healthy Subjects and Subjects With Elevated Lp(a) von Koren, Michael J, Moriarty, Patrick M, Neutel, Joel, Baum, Seth J, Hernandez-Illas, Martha, Weintraub, Howard S, Hellawell, Jennifer, Varrieur, Tracy, Sohn, Winnie, Wang, Huei, Elliott-Davey, Mary, Kassahun, Helina, Watts, Gerald F

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Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRAS G12C mutation: a randomised, open-label, phase 3 trial von de Langen, Adrianus Johannes, Johnson, Melissa L, Mazieres, Julien, Dingemans, Anne-Marie C, Mountzios, Giannis, Pless, Miklos, Wolf, Jürgen, Schuler, Martin, Lena, Hervé, Skoulidis, Ferdinandos, Yoneshima, Yasuto, Kim, Sang-We, Linardou, Helena, Novello, Silvia, van der Wekken, Anthonie J, Chen, Yuanbin, Peters, Solange, Felip, Enriqueta, Solomon, Benjamin J, Ramalingam, Suresh S, Dooms, Christophe, Lindsay, Colin R, Ferreira, Carlos Gil, Blais, Normand, Obiozor, Cynthia C, Wang, Yang, Mehta, Bhakti, Varrieur, Tracy, Ngarmchamnanrith, Gataree, Stollenwerk, Björn, Waterhouse, David, Paz-Ares, Luis

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