RIP1 post-translational modifications von Varfolomeev, Eugene, Vucic, Domagoj

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Tumor Necrosis Factor: An Apoptosis JuNKie? von Varfolomeev, Eugene E, Ashkenazi, Avi

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RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases von Patel, Snahel, Webster, Joshua D., Varfolomeev, Eugene, Kwon, Youngsu C., Cheng, Jason H., Zhang, Juan, Dugger, Debra L., Wickliffe, Kate E., Maltzman, Allie, Sujatha-Bhaskar, Swathi, Bir Kohli, Pawan, Ramaswamy, Sreema, Deshmukh, Gauri, Liederer, Bianca M., Fong, Rina, Hamilton, Greg, Lupardus, Patrick, Caplazi, Patrick, Lee, Wyne P., van Lookeren Campagne, Menno, Johnson, Adam, McKenzie, Brent S., Junttila, Melissa R., Newton, Kim, Vucic, Domagoj

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(Un)expected roles of c-IAPs in apoptotic and NFκB signaling pathways von Varfolomeev, Eugene, Vucic, Domagoj

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Intracellular regulation of TNF activity in health and disease von Varfolomeev, Eugene, Vucic, Domagoj

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Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS von Dominguez, Sara, Varfolomeev, Eugene, Brendza, Robert, Stark, Kim, Tea, Joy, Imperio, Jose, Ngu, Hai, Earr, Timothy, Foreman, Oded, Webster, Joshua D., Easton, Amy, Vucic, Domagoj, Bingol, Baris

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Caspase-8 Serves Both Apoptotic and Nonapoptotic Roles von Kang, Tae-Bong, Ben-Moshe, Tehila, Varfolomeev, Eugene E, Pewzner-Jung, Yael, Yogev, Nir, Jurewicz, Anna, Waisman, Ari, Brenner, Ori, Haffner, Rebecca, Gustafsson, Erika, Ramakrishnan, Parameswaran, Lapidot, Tsvee, Wallach, David

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Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury von Stark, Kimberly, Goncharov, Tatiana, Varfolomeev, Eugene, Xie, Luke, Ngu, Hai, Peng, Ivan, Anderson, Keith R., Verschueren, Erik, Choi, Meena, Kirkpatrick, Donald S., Easton, Amy, Webster, Joshua D., McKenzie, Brent S., Vucic, Domagoj, Bingol, Baris

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Molecular Determinants of Kinase Pathway Activation by Apo2 Ligand/Tumor Necrosis Factor-related Apoptosis-inducing Ligand von Varfolomeev, Eugene, Maecker, Heather, Sharp, Darcie, Lawrence, David, Renz, Mark, Vucic, Domagoj, Ashkenazi, Avi

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IAP antagonist GDC-0917 is more potent than Debio1143 in promoting cell death, c-IAP1 degradation and tumor growth inhibition von Alicke, Bruno, Varfolomeev, Eugene, Lee, Shi Hui Kaylee, Frommlet, Alexandra, Ubhayakar, Savita, Quinn, John G., Fairbrother, Wayne J., Jones, Robert, Gould, Stephen E., Vucic, Domagoj

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Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax von Ashkenazi, Avi, LeBlanc, Heidi, Lawrence, David, Varfolomeev, Eugene, Totpal, Klara, Morlan, John, Schow, Peter, Fong, Sharon, Schwall, Ralph, Sinicropi, Dominick

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TWEAK Attenuates the Transition from Innate to Adaptive Immunity von Maecker, Heather, Varfolomeev, Eugene, Kischkel, Frank, Lawrence, David, LeBlanc, Heidi, Lee, Wyne, Hurst, Stephen, Danilenko, Dimitry, Li, Jun, Filvaroff, Ellen, Yang, Becky, Daniel, Dylan, Ashkenazi, Avi

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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation von Senger, Kate, Pham, Victoria C, Varfolomeev, Eugene, Hackney, Jason A, Corzo, Cesar A, Collier, Jenna, Lau, Vivian W C, Huang, Zhiyu, Hamidzhadeh, Kajal, Caplazi, Patrick, Peng, Ivan, Setiadi, A Francesca, Francis, Ross, Paler-Martinez, Andres, Kwon, Youngsu C, Ramirez-Carrozzi, Vladimir, Sun, Yonglian, Grigg, Patricia W, Roose-Girma, Merone, Jeet, Surinder, Barck, Kai H, Pham, Anna, Ota, Naruhisa, Ha, Connie, Stinson, Jeremy, Guillory, Joseph, Tam, Lucinda, Modrusan, Zora, Emson, Claire, McKenzie, Brent S, Townsend, Michael J, Carano, Richard A D, Warming, Søren, Vucic, Domagoj, DeVoss, Jason, Lee, Wyne P, Lill, Jennie R, Zarrin, Ali A

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Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally von Varfolomeev, Eugene E, Schuchmann, Marcus, Luria, Victor, Chiannilkulchai, Nuchanard, Beckmann, Jacques S, Mett, Igor L, Rebrikov, Denis, Brodianski, Vadim M, Kemper, Oliver C, Kollet, Orit, Lapidot, Tsvee, Soffer, Dror, Sobe, Tama, Avraham, Karen B, Goncharov, Tanya, Holtmann, Helmut, Lonai, Peter, Wallach, David

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Immunoaffinity Enrichment Coupled to Quantitative Mass Spectrometry Reveals Ubiquitin-Mediated Signaling Events von Yu, Kebing, Phu, Lilian, Varfolomeev, Eugene, Bustos, Daisy, Vucic, Domagoj, Kirkpatrick, Donald S.

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Death-Receptor Activation Halts Clathrin-Dependent Endocytosis von Austin, Cary D., Lawrence, David A., Peden, Andrew A., Varfolomeev, Eugene E., Totpal, Klara, De Mazière, Ann M., Klumperman, Judith, Arnott, David, Pham, Victoria, Scheller, Richard H., Ashkenazi, Avi

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Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment von Varfolomeev, Eugene, Izrael-Tomasevic, Anita, Yu, Kebing, Bustos, Daisy, Goncharov, Tatiana, Belmont, Lisa D, Masselot, Alexandre, Bakalarski, Corey E, Kirkpatrick, Donald S, Vucic, Domagoj

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APRIL-Deficient Mice Have Normal Immune System Development von Varfolomeev, Eugene, Kischkel, Frank, Martin, Flavius, Seshasayee, Dhaya, Wang, Hua, Lawrence, David, Olsson, Christine, Tom, Lucrece, Erickson, Sharon, French, Dorothy, Schow, Peter, Grewal, Iqbal S., Ashkenazi, Avi

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X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists von Varfolomeev, Eugene, Alicke, Bruno, Elliott, J.Michael, Zobel, Kerry, West, Kristina, Wong, Harvey, Scheer, Justin M., Ashkenazi, Avi, Gould, Stephen E., Fairbrother, Wayne J., Vucic, Domagoj

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Antagonism of c-IAP and XIAP Proteins Is Required for Efficient Induction of Cell Death by Small-Molecule IAP Antagonists von Ndubaku, Chudi, Varfolomeev, Eugene, Wang, Lan, Zobel, Kerry, Lau, Kevin, Elliott, Linda O, Maurer, Brigitte, Fedorova, Anna V, Dynek, Jasmin N, Koehler, Michael, Hymowitz, Sarah G, Tsui, Vickie, Deshayes, Kurt, Fairbrother, Wayne J, Flygare, John A, Vucic, Domagoj

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