Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis von DEVY, Laetitia, LILI HUANG, VAN GOOL, Reinoud, SEXTON, Daniel J, GUANNAN KUANG, RANK, Douglas, HOGAN, Shannon, PAZMANY, Csaba, YU LU MA, SCHOONBROODT, Sonia, NIXON, Andrew E, LADNER, Robert C, NAA, Laurent, HOET, Rene, HENDERIKX, Paula, TENHOOR, Chris, RABBANI, Shafaat A, VALENTINO, Maria Luisa, WOOD, Clive R, DRANSFIELD, Daniel T, YANAMANDRA, Niranjan, PIETERS, Henk, FRANS, Nicolas, CHANG, Edward, QINGFENG TAO, VANHOVE, Marc, LEJEUNE, Annabelle

Volltext

Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema von Teufel, Daniel P, Bennett, Gavin, Harrison, Helen, van Rietschoten, Katerine, Pavan, Silvia, Stace, Catherine, Le Floch, François, Van Bergen, Tine, Vermassen, Elke, Barbeaux, Philippe, Hu, Tjing-Tjing, Feyen, Jean H. M, Vanhove, Marc

Volltext

A method to assess the robustness of complex mathematical models used for quantitative interpretation of experimental data by nonlinear regression analysis: application to high-aff... von Vanhove, Marc

Volltext

Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19 von Martens, Caroline P., Van Mol, Pierre, Wauters, Joost, Wauters, Els, Gangnus, Tanja, Noppen, Bernard, Callewaert, Hanne, Feyen, Jean H.M., Liesenborghs, Laurens, Heylen, Elisabeth, Jansen, Sander, Pereira, Leydi Carolina Velásquez, Kraisin, Sirima, Guler, Ipek, Engelen, Matthias M., Ockerman, Anna, Van Herck, Anke, Vos, Robin, Vandenbriele, Christophe, Meersseman, Philippe, Hermans, Greet, Wilmer, Alexander, Martinod, Kimberly, Burckhardt, Bjoern B., Vanhove, Marc, Jacquemin, Marc, Verhamme, Peter, Neyts, Johan, Vanassche, Thomas

Volltext

Affinity determination of biomolecules: a kinetic model for the analysis of pre-equilibrium titration curves von Vanhove, Emilie, Vanhove, Marc

Volltext

Robust reconciliated KD from end-point flow cytometry and time-resolved kinetic experiments on live cells, using a universal non-pseudo first-order binding equation von Richalet, Pascale, Westin, Hadis, Vanhove, Marc

Volltext

Mechanism of inactivation of ocriplasmin in porcine vitreous von Aerts, Frans, Noppen, Bernard, Fonteyn, Laetitia, Derua, Rita, Waelkens, Etienne, de Smet, Marc D., Vanhove, Marc

Volltext

Rapid generation of functional human IgG antibodies derived from Fab-on-phage display libraries von Jostock, Thomas, Vanhove, Marc, Brepoels, Eddy, van Gool, Rein, Daukandt, Marc, Wehnert, Anita, van Hegelsom, Rob, Dransfield, Dan, Sexton, Dan, Devlin, Mary, Ley, Art, Müllberg, Jürgen

Volltext

K-D determination from time-resolved experiments on live cells with LigandTracer and reconciliation with end-point flow cytometry measurements von Spiegelberg, Diana, Stenberg, Jonas, Richalet, Pascale, Vanhove, Marc

Volltext

KD determination from time-resolved experiments on live cells with LigandTracer and reconciliation with end-point flow cytometry measurements von Spiegelberg, Diana, Stenberg, Jonas, Richalet, Pascale, Vanhove, Marc

Volltext

A novel assay based on pre-equilibrium titration curves for the determination of enzyme inhibitor binding kinetics von Noppen, Bernard, Vanbelle, Anouk, Stitt, Alan W., Vanhove, Marc

Volltext

A novel, label‐free, pre‐equilibrium assay to determine the association and dissociation rate constants of therapeutic antibodies on living cells von Janezic, Eric M., Doan, Alexander, Mai, Elaine, Bravo, Daniel D., Wang, Jianyong, Kim, Hok Seon, Spiess, Christoph, Bewley, Kathryn, ElSohly, Adel, Liang, Wei‐Ching, Koerber, James T., Richalet, Pascale, Vanhove, Marc, Comps‐Agrar, Laetitia

Volltext

Rapid kinetic-based screening of human Fab fragments von Steukers, Mieke, Schaus, Jean-Michel, van Gool, Reinoud, Hoyoux, Anne, Richalet, Pascale, Sexton, Daniel J., Nixon, Andrew E., Vanhove, Marc

Volltext

The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders von Hu, Tjing-Tjing, Vanhove, Marc, Porcu, Michaël, Van Hove, Inge, Van Bergen, Tine, Jonckx, Bart, Barbeaux, Philippe, Vermassen, Elke, Feyen, Jean H.M.

Volltext

Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 1. THR-149 von Vanhove, Marc, Noppen, Bernard, Wagner, Jean-Marc, Van Bergen, Tine, Barbeaux, Philippe, Stitt, Alan W.

Volltext

Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 2. THR-687 von Vanhove, Marc, Wagner, Jean-Marc, Noppen, Bernard, Jonckx, Bart, Vermassen, Elke, Stitt, Alan W.

Volltext

Pharmacokinetics of ocriplasmin in vitreous von de Smet, Marc D, Jonckx, Bart, Vanhove, Marc, van Calster, Joachim, Stalmans, Peter, Stassen, Jean Marie

Volltext

Intravitreally Injected Fluid Dispersion: Importance of Injection Technique von Willekens, Koen, Reyns, Geert, Diricx, Marjan, Vanhove, Marc, Noppen, Bernard, Coudyzer, Walter, Ni, Yicheng, Feyen, Jean H M, Stalmans, Peter

Volltext

The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders von Hu, Tjing-Tjing, Vanhove, Marc, Porcu, Michael, Van Hove, Inge, Van Bergen, Tine, Jonckx, Bart, Barbeaux, Philippe, Vermassen, Elke, Feyen, Jean H.M

Volltext

Intravitreally Injected Fluid Dispersion: Importance of Injection Technique von Willekens, Koen, Reyns, Geert, Diricx, Marjan, Vanhove, Marc, Noppen, Bernard, Coudyzer, Walter, Ni, Yicheng, Feyen, Jean H.M, Stalmans, Peter

Volltext