The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis von Chen, Han-Jou, Mitchell, Jacqueline C, Novoselov, Sergey, Miller, Jack, Nishimura, Agnes L, Scotter, Emma L, Vance, Caroline A, Cheetham, Michael E, Shaw, Christopher E

Volltext

Striking phenotypic variation in a family with the P506S UBQLN2 mutation including amyotrophic lateral sclerosis, spastic paraplegia, and frontotemporal dementia von Gkazi, Soragia Athina, Troakes, Claire, Topp, Simon, Miller, Jack W., Vance, Caroline A., Sreedharan, Jemeen, Al-Chalabi, Ammar, Kirby, Janine, Shaw, Pamela J., Al-Sarraj, Safa, King, Andrew, Smith, Bradley N., Shaw, Christopher E.

Volltext

C9ORF72 and UBQLN2 mutations are causes of amyotrophic lateral sclerosis in New Zealand: a genetic and pathologic study using banked human brain tissue von Scotter, Emma L., Smyth, Leon, Bailey, J​ames W.T., Wong, Chun-Hao, de Majo, Martina, Vance, Caroline A., Synek, Beth J., Turner, Clinton, Pereira, Jennifer, Charleston, Alison, Waldvogel, Henry J., Curtis, Maurice A., Dragunow, Mike, Shaw, Christopher E., Smith, Bradley N., Faull, Richard L.M.

Volltext

The CHCHD10 P34S variant is not associated with ALS in a UK cohort of familial and sporadic patients von Wong, Chun Hao, Topp, Simon, Gkazi, Athina Soragia, Troakes, Claire, Miller, Jack W, de Majo, Martina, Kirby, Janine, Shaw, Pamela J, Morrison, Karen E, de Belleroche, Jacqueline, Vance, Caroline A, Al-Chalabi, Ammar, Al-Sarraj, Safa, Shaw, Christopher E, Smith, Bradley N

Volltext

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways von Cirulli, Elizabeth T., Lasseigne, Brittany N., Petrovski, Slavé, Sapp, Peter C., Dion, Patrick A., Leblond, Claire S., Couthouis, Julien, Lu, Yi-Fan, Wang, Quanli, Krueger, Brian J., Ren, Zhong, Keebler, Jonathan, Han, Yujun, Levy, Shawn E., Boone, Braden E., Wimbish, Jack R., Waite, Lindsay L., Jones, Angela L., Carulli, John P., Day-Williams, Aaron G., Staropoli, John F., Xin, Winnie W., Chesi, Alessandra, Raphael, Alya R., McKenna-Yasek, Diane, Cady, Janet, de Jong, J. M. B. Vianney, Kenna, Kevin P., Smith, Bradley N., Topp, Simon, Miller, Jack, Gkazi, Athina, Al-Chalabi, Ammar, van den Berg, Leonard H., Veldink, Jan, Silani, Vincenzo, Ticozzi, Nicola, Shaw, Christopher E., Baloh, Robert H., Appel, Stanley, Simpson, Ericka, Lagier-Tourenne, Clotilde, Pulst, Stefan M., Gibson, Summer, Trojanowski, John Q., Elman, Lauren, McCluskey, Leo, Grossman, Murray, Shneider, Neil A., Chung, Wendy K., Ravits, John M., Glass, Jonathan D., Sims, Katherine B., Van Deerlin, Vivianna M., Maniatis, Tom, Hayes, Sebastian D., Ordureau, Alban, Swarup, Sharan, Landers, John, Baas, Frank, Allen, Andrew S., Bedlack, Richard S., Harper, J. Wade, Gitler, Aaron D., Rouleau, Guy A., Brown, Robert, Harms, Matthew B., Cooper, Gregory M., Harris, Tim, Myers, Richard M., Goldstein, David B.

Volltext

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1 von Ahmeti, Kreshnik B, Ajroud-Driss, Senda, Al-Chalabi, Ammar, Andersen, Peter M, Armstrong, Jennifer, Birve, Anne, Blauw, Hylke M, Brown, Robert H, Bruijn, Lucie, Chen, Wenjie, Chio, Adriano, Comeau, Mary C, Cronin, Simon, Diekstra, Frank P, Soraya Gkazi, Athina, Glass, Jonathan D, Grab, Josh D, Groen, Ewout J, Haines, Jonathan L, Hardiman, Orla, Heller, Scott, Huang, Jie, Hung, Wu-Yen, Jaworski, James M, Jones, Ashley, Khan, Humaira, Landers, John E, Langefeld, Carl D, Leigh, P Nigel, Marion, Miranda C, McLaughlin, Russell L, Meininger, Vincent, Melki, Judith, Miller, Jack W, Mora, Gabriele, Pericak-Vance, Margaret A, Rampersaud, Evadnie, Robberecht, Wim, Russell, Laurie P, Salachas, Francois, Saris, Christiaan G, Shatunov, Aleksey, Shaw, Christopher E, Siddique, Nailah, Siddique, Teepu, Smith, Bradley N, Sufit, Robert, Topp, Simon, Traynor, Bryan J, Vance, Caroline, van Damme, Philip, van den Berg, Leonard H, van Es, Michael A, van Vught, Paul W, Veldink, Jan H, Yang, Yi, Zheng, J G

Volltext

Role of the sympathetic nervous system in regulation of the sodium glucose cotransporter 2 von Matthews, Vance B, Elliot, Rosemary H, Rudnicka, Caroline, Hricova, Jana, Herat, Lakshini, Schlaich, Markus P

Volltext

An Independent Evaluation of the Younger Dryas Extraterrestrial Impact Hypothesis von Surovell, Todd A., Holliday, Vance T., Gingerich, Joseph A. M., Ketron, Caroline, Haynes, C. Vance, Hilman, Ilene, Wagner, Daniel P., Johnson, Eileen, Claeys, Philippe

Volltext

S‐Methyl Cysteine Sulfoxide Does Not Ameliorate Weight Gain or Hyperlipidemia in Mice Fed a High‐Fat Diet von Hill, Caroline R., Shafaei, Armaghan, Matthews, Vance B., Ward, Natalie C., Croft, Kevin D., Lewis, Joshua R., Hodgson, Jonathan M., Balmer, Lois, Blekkenhorst, Lauren C.

Volltext

Tidally Induced Magmatic Pulses on the Oceanic Floor of Jupiter's Moon Europa von Běhounková, Marie, Tobie, Gabriel, Choblet, Gaël, Kervazo, Mathilde, Melwani Daswani, Mohit, Dumoulin, Caroline, Vance, Steven D.

Volltext

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species von Scotter, Emma L, Vance, Caroline, Nishimura, Agnes L, Lee, Youn-Bok, Chen, Han-Jou, Urwin, Hazel, Sardone, Valentina, Mitchell, Jacqueline C, Rogelj, Boris, Rubinsztein, David C, Shaw, Christopher E

Volltext

Selective Gold Precipitation by a Tertiary Diamide Driven by Thermodynamic Control von Vance, Susanna S. M., Mojsak, Mateusz, Kinsman, Luke M. M., Rae, Rebecca, Kirk, Caroline, Love, Jason B., Morrison, Carole A.

Volltext

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules von Vance, Caroline, Scotter, Emma L, Nishimura, Agnes L, Troakes, Claire, Mitchell, Jacqueline C, Kathe, Claudia, Urwin, Hazel, Manser, Catherine, Miller, Christopher C, Hortobágyi, Tibor, Dragunow, Mike, Rogelj, Boris, Shaw, Christopher E

Volltext

Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2 von Pankratz, Nathan, Beecham, Gary W., DeStefano, Anita L., Dawson, Ted M., Doheny, Kimberly F., Factor, Stewart A., Hamza, Taye H., Hung, Albert Y., Hyman, Bradley T., Ivinson, Adrian J., Krainc, Dmitri, Latourelle, Jeanne C., Clark, Lorraine N., Marder, Karen, Martin, Eden R., Mayeux, Richard, Ross, Owen A., Scherzer, Clemens R., Simon, David K., Tanner, Caroline, Vance, Jeffery M., Wszolek, Zbigniew K., Zabetian, Cyrus P., Myers, Richard H., Payami, Haydeh, Scott, William K., Foroud, Tatiana

Volltext

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6 von Vance, Caroline, Rogelj, Boris, Hortobágyi, Tibor, De Vos, Kurt J, Nishimura, Agnes Lumi, Sreedharan, Jemeen, Hu, Xun, Smith, Bradley, Ruddy, Deborah, Wright, Paul, Ganesalingam, Jeban, Williams, Kelly L, Tripathi, Vineeta, Al-Saraj, Safa, Al-Chalabi, Ammar, Leigh, P. Nigel, Blair, Ian P, Nicholson, Garth, de Belleroche, Jackie, Gallo, Jean-Marc, Miller, Christopher C, Shaw, Christopher E

Volltext

Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic von Lee, Youn-Bok, Chen, Han-Jou, Peres, João N., Gomez-Deza, Jorge, Attig, Jan, Štalekar, Maja, Troakes, Claire, Nishimura, Agnes L., Scotter, Emma L., Vance, Caroline, Adachi, Yoshitsugu, Sardone, Valentina, Miller, Jack W., Smith, Bradley N., Gallo, Jean-Marc, Ule, Jernej, Hirth, Frank, Rogelj, Boris, Houart, Corinne, Shaw, Christopher E.

Volltext

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis von Sreedharan, Jemeen, Blair, Ian P, Tripathi, Vineeta B, Hu, Xun, Vance, Caroline, Rogelj, Boris, Ackerley, Steven, Durnall, Jennifer C, Williams, Kelly L, Buratti, Emanuele, Baralle, Francisco, de Belleroche, Jacqueline, Mitchell, J. Douglas, Leigh, P. Nigel, Al-Chalabi, Ammar, Miller, Christopher C, Nicholson, Garth, Shaw, Christopher E

Volltext

Optogenetic control of striatal dopamine release in rats von Bass, Caroline E, Grinevich, Valentina P, Vance, Zachary B, Sullivan, Ryan P, Bonin, Keith D, Budygin, Evgeny A

Volltext

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion von Mitchell, Jacqueline C., McGoldrick, Philip, Vance, Caroline, Hortobagyi, Tibor, Sreedharan, Jemeen, Rogelj, Boris, Tudor, Elizabeth L., Smith, Bradley N., Klasen, Christian, Miller, Christopher C. J., Cooper, Jonathan D., Greensmith, Linda, Shaw, Christopher E.

Volltext

Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development von Thomas-Jinu, Swapna, Gordon, Patricia M., Fielding, Triona, Taylor, Richard, Smith, Bradley N., Snowden, Victoria, Blanc, Eric, Vance, Caroline, Topp, Simon, Wong, Chun-Hao, Bielen, Holger, Williams, Kelly L., McCann, Emily P., Nicholson, Garth A., Pan-Vazquez, Alejandro, Fox, Archa H., Bond, Charles S., Talbot, William S., Blair, Ian P., Shaw, Christopher E., Houart, Corinne

Volltext