Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays von VanDussen, Kelli L, Marinshaw, Jeffrey M, Shaikh, Nurmohammad, Miyoshi, Hiroyuki, Moon, Clara, Tarr, Phillip I, Ciorba, Matthew A, Stappenbeck, Thaddeus S

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L-WRN conditioned medium for gastrointestinal epithelial stem cell culture shows replicable batch-to-batch activity levels across multiple research teams von VanDussen, Kelli L., Sonnek, Naomi M., Stappenbeck, Thaddeus S.

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Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells von Wang, Yi, Chiang, I-Ling, Ohara, Takahiro E., Fujii, Satoru, Cheng, Jiye, Muegge, Brian D., Ver Heul, Aaron, Han, Nathan D., Lu, Qiuhe, Xiong, Shanshan, Chen, Feidi, Lai, Chin-Wen, Janova, Hana, Wu, Renee, Whitehurst, Charles E., VanDussen, Kelli L., Liu, Ta-Chiang, Gordon, Jeffrey I., Sibley, L. David, Stappenbeck, Thaddeus S.

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Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium von Miyoshi, Hiroyuki, VanDussen, Kelli L, Malvin, Nicole P, Ryu, Stacy H, Wang, Yi, Sonnek, Naomi M, Lai, Chin‐Wen, Stappenbeck, Thaddeus S

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Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells von VanDussen, Kelli L, Carulli, Alexis J, Keeley, Theresa M, Patel, Sanjeevkumar R, Puthoff, Brent J, Magness, Scott T, Tran, Ivy T, Maillard, Ivan, Siebel, Christian, Kolterud, Åsa, Grosse, Ann S, Gumucio, Deborah L, Ernst, Stephen A, Tsai, Yu-Hwai, Dempsey, Peter J, Samuelson, Linda C

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Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate von VanDussen, Kelli L., Samuelson, Linda C.

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Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiot... von Alvarado, David M., Chen, Baosheng, Iticovici, Micah, Thaker, Ameet I., Dai, Nattalie, VanDussen, Kelli L., Shaikh, Nurmohammad, Lim, Chai K., Guillemin, Gilles J., Tarr, Phillip I., Ciorba, Matthew A.

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Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation von Liu, Ta-Chiang, Kern, Justin T., Jain, Umang, Sonnek, Naomi M., Xiong, Shanshan, Simpson, Katherine F., VanDussen, Kelli L., Winkler, Emma S., Haritunians, Talin, Malique, Atika, Lu, Qiuhe, Sasaki, Yo, Storer, Chad, Diamond, Michael S., Head, Richard D., McGovern, Dermot P.B., Stappenbeck, Thaddeus S.

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IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation von Overcast, Garrett R, Meibers, Hannah E, Eshleman, Emily M, Saha, Irene, Waggoner, Lisa, Patel, Krupaben N, Jain, Viral G, Haslam, David B, Alenghat, Theresa, VanDussen, Kelli L, Pasare, Chandrashekhar

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Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration von Jain, Umang, Lai, Chin-Wen, Xiong, Shanshan, Goodwin, Victoria M., Lu, Qiuhe, Muegge, Brian D., Christophi, George P., VanDussen, Kelli L., Cummings, Bethany P., Young, Erick, Hambor, John, Stappenbeck, Thaddeus S.

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Notch signaling regulates gastric antral LGR5 stem cell function von Demitrack, Elise S, Gifford, Gail B, Keeley, Theresa M, Carulli, Alexis J, VanDussen, Kelli L, Thomas, Dafydd, Giordano, Thomas J, Liu, Zhenyi, Kopan, Raphael, Samuelson, Linda C

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Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn's disease von Liu, Ta-Chiang, Kern, Justin T, VanDussen, Kelli L, Xiong, Shanshan, Kaiko, Gerard E, Wilen, Craig B, Rajala, Michael W, Caruso, Roberta, Holtzman, Michael J, Gao, Feng, McGovern, Dermot Pb, Nunez, Gabriel, Head, Richard D, Stappenbeck, Thaddeus S

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The Promise of Patient-Derived Colon Organoids to Model Ulcerative Colitis von Ojo, Babajide A, VanDussen, Kelli L, Rosen, Michael J

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Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth von Funkhouser-Jones, Lisa J., Xu, Rui, Wilke, Georgia, Fu, Yong, Schriefer, Lawrence A., Makimaa, Heyde, Rodgers, Rachel, Kennedy, Elizabeth A., VanDussen, Kelli L., Stappenbeck, Thaddeus S., Baldridge, Megan T., Sibley, L. David

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Genetic Variants Synthesize to Produce Paneth Cell Phenotypes That Define Subtypes of Crohn's Disease von VanDussen, Kelli L, Liu, Ta-Chiang, Li, Dalin, Towfic, Fadi, Modiano, Nir, Winter, Rachel, Haritunians, Talin, Taylor, Kent D, Dhall, Deepti, Targan, Stephan R, Xavier, Ramnik J, McGovern, Dermot P.B, Stappenbeck, Thaddeus S

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Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease von VanDussen, Kelli L., Stojmirović, Aleksandar, Li, Katherine, Liu, Ta-Chiang, Kimes, Patrick K., Muegge, Brian D., Simpson, Katherine F., Ciorba, Matthew A., Perrigoue, Jacqueline G., Friedman, Joshua R., Towne, Jennifer E., Head, Richard D., Stappenbeck, Thaddeus S.

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Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium von Miyoshi, Hiroyuki, VanDussen, Kelli L, Malvin, Nicole P, Ryu, Stacy H, Wang, Yi, Sonnek, Naomi M, Lai, Chin‐Wen, Stappenbeck, Thaddeus S

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Neonatal Mouse Gut Metabolites Influence Cryptosporidium parvum Infection in Intestinal Epithelial Cells von VanDussen, Kelli L, Funkhouser-Jones, Lisa J, Akey, Marianna E, Schaefer, Deborah A, Ackman, Kevin, Riggs, Michael W, Stappenbeck, Thaddeus S, Sibley, L David

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ADAM10 Regulates Notch Function in Intestinal Stem Cells of Mice von Tsai, Yu-Hwai, VanDussen, Kelli L, Sawey, Eric T, Wade, Alex W, Kasper, Chelsea, Rakshit, Sabita, Bhatt, Riha G, Stoeck, Alex, Maillard, Ivan, Crawford, Howard C, Samuelson, Linda C, Dempsey, Peter J

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Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity von Strine, Madison S., Alfajaro, Mia Madel, Graziano, Vincent R., Song, Jaewon, Hsieh, Leon L., Hill, Ryan, Guo, Jun, VanDussen, Kelli L., Orchard, Robert C., Baldridge, Megan T., Lee, Sanghyun, Wilen, Craig B.

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