Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants von Vago, Juliana P, Valdrighi, Natália, Blaney-Davidson, Esmeralda N, Hornikx, Daniel L A H, Neefjes, Margot, Barba-Sarasua, María E, Thielen, Nathalie G M, van den Bosch, Martijn H J, van der Kraan, Peter M, Koenders, Marije I, Amaral, Flávio A, van de Loo, Fons A J

Volltext

Innate Immunity and Sex: Distinct Inflammatory Profiles Associated with Murine Pain in Acute Synovitis von Valdrighi, Natália, Blom, Arjen B, Vago, Juliana P, van Beuningen, Henk M, Vitters, Elly L, Helsen, Monique M, Walgreen, Birgitte, Arntz, Onno J, Koenders, Marije I, van der Kraan, Peter M, Blaney Davidson, Esmeralda N, van de Loo, Fons A J

Volltext

Functional Tissue Analysis Reveals Successful Cryopreservation of Human Osteoarthritic Synovium von Broeren, Mathijs G A, de Vries, Marieke, Bennink, Miranda B, van Lent, Peter L E M, van der Kraan, Peter M, Koenders, Marije I, Thurlings, Rogier M, van de Loo, Fons A J

Volltext

Disease-Regulated Gene Therapy with Anti-Inflammatory Interleukin-10 Under the Control of the CXCL10 Promoter for the Treatment of Rheumatoid Arthritis von Broeren, Mathijs G A, de Vries, Marieke, Bennink, Miranda B, Arntz, Onno J, Blom, Arjen B, Koenders, Marije I, van Lent, Peter L E M, van der Kraan, Peter M, van den Berg, Wim B, van de Loo, Fons A J

Volltext

Higher efficacy of anti-IL-6/IL-21 combination therapy compared to monotherapy in the induction phase of Th17-driven experimental arthritis von Roeleveld, Debbie M, Marijnissen, Renoud J, Walgreen, Birgitte, Helsen, Monique M, van den Bersselaar, Liduine, van de Loo, Fons A, van Lent, Peter L, van der Kraan, Peter M, van den Berg, Wim B, Koenders, Marije I

Volltext

Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance von Netea, Mihai G, Joosten, Leo A B, Lewis, Eli, Jensen, Dalan R, Voshol, Peter J, Kullberg, Bart Jan, Tack, Cees J, van Krieken, Han, Kim, Soo-Hyun, Stalenhoef, Anton F, van de Loo, Fons A, Verschueren, Ineke, Pulawa, Leslie, Akira, Shizuo, Eckel, Robert H, Dinarello, Charles A, van den Berg, Wim, van der Meer, Jos W M

Volltext

The in-vivo use of superparamagnetic iron oxide nanoparticles to detect inflammation elicits a cytokine response but does not aggravate experimental arthritis von Vermeij, Eline A, Koenders, Marije I, Bennink, Miranda B, Crowe, Lindsey A, Maurizi, Lionel, Vallée, Jean-Paul, Hofmann, Heinrich, van den Berg, Wim B, van Lent, Peter L E M, van de Loo, Fons A J

Volltext

Intravenous delivery of HIV-based lentiviral vectors preferentially transduces F4/80+ and Ly-6C+ cells in spleen, important target cells in autoimmune arthritis von van den Brand, Ben T, Vermeij, Eline A, Waterborg, Claire E J, Arntz, Onno J, Kracht, Michael, Bennink, Miranda B, van den Berg, Wim B, van de Loo, Fons A J

Volltext

The influence of alcohol (0.5‰) on the control and manoeuvring level of driving behaviour, finding measures to assess driving impairment: A simulator study von van Dijken, J.H., Veldstra, J.L., van de Loo, A.J.A.E., Verster, J.C., van der Sluiszen, N.N.J.J.M., Vermeeren, A., Ramaekers, J.G., Brookhuis, K.A., de Waard, D.

Volltext

S100A8/A9, a potent serum and molecular imaging biomarker for synovial inflammation and joint destruction in seronegative experimental arthritis von Geven, Edwin J W, van den Bosch, Martijn H J, Di Ceglie, Irene, Ascone, Giuliana, Abdollahi-Roodsaz, Shahla, Sloetjes, Annet W, Hermann, Sven, Schäfers, Michael, van de Loo, Fons A J, van der Kraan, Peter M, Koenders, Marije I, Foell, Dirk, Roth, Johannes, Vogl, Thomas, van Lent, Peter L E M

Volltext

Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis von Di Ceglie, Irene, Ascone, Giuliana, Cremers, Niels A J, Sloetjes, Annet W, Walgreen, Birgitte, Vogl, Thomas, Roth, Johannes, Verbeek, J Sjef, van de Loo, Fons A J, Koenders, Marije I, van der Kraan, Peter M, Blom, Arjen B, van den Bosch, Martijn H J, van Lent, Peter L E M

Volltext

IL-32, a Proinflammatory Cytokine in Rheumatoid Arthritis von Joosten, Leo A. B., Netea, Mihai G., Kim, Soo-Hyun, Yoon, Do-Young, Oppers-Walgreen, Birgitte, Radstake, Timothy R. D., Barrera, Pilar, van de Loo, Fons A. J., Dinarello, Charles A., van den Berg, Wim B.

Volltext

The serum amyloid A3 promoter-driven luciferase reporter mice is a valuable tool to image early renal fibrosis development and shows the therapeutic effect of glucosyl-hesperidin t... von Kumrungsee, Thanutchaporn, Kariya, Taishi, Hashimoto, Kotaro, Koyano, Takayuki, Yazawa, Nao, Hashimoto, Takao, Sanada, Yohei, Matsuyama, Makoto, Sotomaru, Yusuke, Sakurai, Hiroaki, van de Loo, Fons A. J., Yanaka, Noriyuki

Volltext

Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane von Broeren, Mathijs G A, de Vries, Marieke, Bennink, Miranda B, Arntz, Onno J, van Lent, Peter L E M, van der Kraan, Peter M, van den Berg, Wim B, van den Hoogen, Frank H J, Koenders, Marije I, van de Loo, Fons A J

Volltext

Genetic modification of ER‐Hoxb8 osteoclast precursors using CRISPR/Cas9 as a novel way to allow studies on osteoclast biology von Di Ceglie, Irene, Akker, Guus G. H., Ascone, Giuliana, Harkel, Bas, Häcker, Hans, Loo, Fons A. J., Koenders, Marije I., Kraan, Peter M., Vries, Teun J., Vogl, Thomas, Roth, Johannes, Lent, Peter L. E. M.

Volltext

Patient involvement in basic rheumatology research at Nijmegen: a three year’s responsive evaluation of added value, pitfalls and conditions for success von de Wit, Maarten P. T., Koenders, M. I., Neijland, Y., van den Hoogen, F. H. J., van der Kraan, P. M., van de Loo, F. A. J., Berkers, H., Lieon, M., van Caam, A., van den Ende, C.

Volltext

Alcohol metabolism in hangover sensitive versus hangover resistant social drinkers von Mackus, M., van Schrojenstein Lantman, M., Van de Loo, A.J.A.E., Kraneveld, A.D., Garssen, J., Brookhuis, K.A., Verster, J.C.

Volltext

IL-1-Independent Role of IL-17 in Synovial Inflammation and Joint Destruction During Collagen-Induced Arthritis von Lubberts, Erik, Joosten, Leo A. B, Oppers, Birgitte, van den Bersselaar, Liduine, Coenen-de Roo, Christina J. J, Kolls, Jay K, Schwarzenberger, Paul, van de Loo, Fons A. J, van den Berg, Wim B

Volltext

Control in the Hospital by Extensive Clinical rules for Unplanned hospitalizations in older Patients (CHECkUP); study design of a multicentre randomized study von Linkens, Aimée E M J H, Milosevic, Vanja, van Nie, Noémi, Zwietering, Anne, de Leeuw, Peter W, van den Akker, Marjan, Schols, Jos M G A, Evers, Silvia M A A, Gonzalvo, Carlota Mestres, Winkens, Bjorn, van de Loo, Bob P A, de Wolf, Louis, Peeters, Lucretia, de Ree, Monique, Spaetgens, Bart, Hurkens, Kim P G M, van der Kuy, Hugo M

Volltext

High LDL levels lead to increased synovial inflammation and accelerated ectopic bone formation during experimental osteoarthritis von de Munter, W, van den Bosch, M.H, Slöetjes, A.W, Croce, K.J, Vogl, T, Roth, J, Koenders, M.I, van de Loo, F.A, van den Berg, W.B, van der Kraan, P.M, van Lent, P.L

Volltext