Early Bactericidal Activity of High-Dose Rifampin in Patients with Pulmonary Tuberculosis Evidenced by Positive Sputum Smears von DIACON, A. H, PATIENTIA, R. F, VENTER, A, VAN HELDEN, P. D, SMITH, P. J, MCILLERON, H, MARITZ, J. S, DONALD, P. R

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Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates von Black, P A, de Vos, M, Louw, G E, van der Merwe, R G, Dippenaar, A, Streicher, E M, Abdallah, A M, Sampson, S L, Victor, T C, Dolby, T, Simpson, J A, van Helden, P D, Warren, R M, Pain, A

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A Balancing Act: Efflux/Influx in Mycobacterial Drug Resistance von LOUW, G. E, WARREN, R. M, VAN PITTIUS, N. C. Gey, MCEVOY, C. R. E, VAN HELDEN, P. D, VICTOR, T. C

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Recently Evolved Sublineage of the Mycobacterium tuberculosis Beijing Strain Family Is Associated with an Increased Ability to Spread and Cause Disease von Hanekom, M, van der Spuy, G.D, Streicher, E, Ndabambi, S.L, McEvoy, C.R.E, Kidd, M, Beyers, N, Victor, T.C, van Helden, P.D, Warren, R.M

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Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages von Phelan, Jody E, Coll, Francesc, Bergval, Indra, Anthony, Richard M, Warren, Rob, Sampson, Samantha L, Gey van Pittius, Nicolaas C, Glynn, Judith R, Crampin, Amelia C, Alves, Adriana, Bessa, Theolis Barbosa, Campino, Susana, Dheda, Keertan, Grandjean, Louis, Hasan, Rumina, Hasan, Zahra, Miranda, Anabela, Moore, David, Panaiotov, Stefan, Perdigao, Joao, Portugal, Isabel, Sheen, Patricia, de Oliveira Sousa, Erivelton, Streicher, Elizabeth M, van Helden, Paul D, Viveiros, Miguel, Hibberd, Martin L, Pain, Arnab, McNerney, Ruth, Clark, Taane G

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Rate of Reinfection Tuberculosis after Successful Treatment Is Higher than Rate of New Tuberculosis von Verver, Suzanne, Warren, Robin M, Beyers, Nulda, Richardson, Madalene, van der Spuy, Gian D, Borgdorff, Martien W, Enarson, Donald A, Behr, Marcel A, van Helden, Paul D

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Differentiation of Mycobacterium tuberculosis complex by PCR amplification of genomic regions of difference [Short Communication] von WARREN, R. M, VAN PITTIUS, N. C. Gey, VAN HELDEN, P. D, BARNARD, M, HESSELING, A, ENGELKE, E, DE KOCK, M, GUTIERREZ, M. C, CHEGE, G. K, VICTOR, T. C, HOAL, E. G

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Mycobacterium tuberculosis strains with the Beijing genotype demonstrate variability in virulence associated with transmission von Aguilar L, D, Hanekom, M, Mata, D, Gey van Pittius, N.C, van Helden, P.D, Warren, R.M, Hernandez-Pando, R

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Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis von Barreiro, Luis B, Neyrolles, Olivier, Babb, Chantal L, Tailleux, Ludovic, Quach, Hélène, McElreavey, Ken, Helden, Paul D van, Hoal, Eileen G, Gicquel, Brigitte, Quintana-Murci, Lluis

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Time to liquid culture positivity can substitute for colony counting on agar plates in early bactericidal activity studies of antituberculosis agents von Diacon, A.H., Maritz, J.S., Venter, A., van Helden, P.D., Dawson, R., Donald, P.R.

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Baseline sputum time to detection predicts month two culture conversion and relapse in non-HIV-infected patients von Hesseling, A C, Walzl, G, Enarson, D A, Carroll, N M, Duncan, K, Lukey, P T, Lombard, C, Donald, P R, Lawrence, K A, Gie, R P, van Helden, P D, Beyers, N

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Bacille Calmette-Guérin Vaccine—Induced Disease in HIV-Infected and HIV-Uninfected Children von Hesseling, A. C., Rabie, H., Marais, B. J., Manders, M., Lips, M., Schaaf, H. S., Gie, R. P., Cotton, M. F., van Helden, P. D., Warren, R. M., Beyers, N.

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Patients with Active Tuberculosis often Have Different Strains in the Same Sputum Specimen von Warren, Robin M, Victor, Thomas C, Streicher, Elizabeth M, Richardson, Madalene, Beyers, Nulda, van Pittius, Nicolaas C. Gey, van Helden, Paul D

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inhA promoter mutations: a gateway to extensively drug-resistant tuberculosis in South Africa? von MULLER, B, STREICHER, E. M, VICTOR, T. C, VAN HEIDEN, P. D, WARREN, R. M, HOEK, K. G. P, TAIT, M, TROLLIP, A, BOSMAN, M. E, COETZEE, G. J, CHABULA-NXIWENI, E. M, HOOSAIN, E, GEY VAN PITTIUS, N. C

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Spoligotype Signatures in the Mycobacterium tuberculosis Complex von Streicher, E.M, Victor, T.C, van der Spuy, G, Sola, C, Rastogi, N, van Helden, P.D, Warren, R.M

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Proportion of tuberculosis transmission that takes place in households in a high-incidence area von Verver, Suzanne, Warren, Robin M, Munch, Zahn, Richardson, Madalene, van der Spuy, Gian D, Borgdorff, Martien W, Behr, Marcel A, Beyers, Nulda, van Helden, Paul D

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Reinfection and Mixed Infection Cause Changing Mycobacterium tuberculosis Drug-Resistance Patterns von van Rie, Annelies, Victor, Thomas C, Richardson, Madalene, Johnson, Rabia, van der Spuy, Gian D, Murray, Emma J, Beyers, Nulda, van Pittius, Nico C. Gey, van Helden, Paul D, Warren, Robin M

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Gene-Expression Patterns in Whole Blood Identify Subjects at Risk for Recurrent Tuberculosis von Mistry, Rohit, Cliff, Jacqueline M., Clayton, Christopher L., Beyers, Nulda, Mohamed, Yasmin S., Wilson, Paul A., Dockrell, Hazel M., Wallace, Don M., van Helden, Paul D., Duncan, Ken, Lukey, Pauline T.

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Association between tuberculosis and a polymorphic NFκB binding site in the interferon γ gene von Rossouw, Manda, Nel, Hendrik J, Cooke, Graham S, van Helden, Paul D, Hoal, Eileen G

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Mutations in the rrs A1401G Gene and Phenotypic Resistance to Amikacin and Capreomycin in Mycobacterium tuberculosis von Sirgel, Frederick A., Tait, Marisa, Warren, Robin M., Streicher, Elizabeth M., Böttger, Erik C., van Helden, Paul D., Gey van Pittius, Nicolaas C., Coetzee, Gerrit, Hoosain, Ebrahim Y., Chabula-Nxiweni, Mamisa, Hayes, Cindy, Victor, Thomas C., Trollip, André

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