Targeted drug delivery by gemtuzumab ozogamicin: mechanism-based mathematical model for treatment strategy improvement and therapy individualization von Jager, Eva, van der Velden, Vincent H J, te Marvelde, Jeroen G, Walter, Roland B, Agur, Zvia, Vainstein, Vladimir

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Severe COVID-19 Is Characterised by Perturbations in Plasma Amines Correlated with Immune Response Markers, and Linked to Inflammation and Oxidative Stress von Karu, Naama, Kindt, Alida, van Gammeren, Adriaan J, Ermens, Anton A M, Harms, Amy C, Portengen, Lutzen, Vermeulen, Roel C H, Dik, Willem A, Langerak, Anton W, van der Velden, Vincent H J, Hankemeier, Thomas

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Plasma Oxylipins and Their Precursors Are Strongly Associated with COVID-19 Severity and with Immune Response Markers von Karu, Naama, Kindt, Alida, Lamont, Lieke, van Gammeren, Adriaan J, Ermens, Anton A M, Harms, Amy C, Portengen, Lutzen, Vermeulen, Roel C H, Dik, Willem A, Langerak, Anton W, van der Velden, Vincent H J, Hankemeier, Thomas

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Association of Altered Plasma Lipidome with Disease Severity in COVID-19 Patients von Zhang, Zhengzheng, Karu, Naama, Kindt, Alida, Singh, Madhulika, Lamont, Lieke, van Gammeren, Adriaan J, Ermens, Anton A M, Harms, Amy C, Portengen, Lutzen, Vermeulen, Roel C H, Dik, Willem A, Langerak, Anton W, van der Velden, Vincent H J, Hankemeier, Thomas

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The Evolving Landscape of Flowcytometric Minimal Residual Disease Monitoring in B-Cell Precursor Acute Lymphoblastic Leukemia von Verbeek, Martijn W C, van der Velden, Vincent H J

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Minimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standardized technologies von van Dongen, Jacque.J.M., van der Velden, Vincent.H.J., Brüggemann, Monika, Orfao, Alberto

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Potential and pitfalls of whole transcriptome-based immunogenetic marker identification in acute lymphoblastic leukemia; a EuroMRD and EuroClonality-NGS Working Group study von van der Velden, Vincent H. J., Brüggemann, Monika, Cazzaniga, Giovanni, Scheijen, Blanca, Tops, Bastiaan, Trka, Jan, Pal, Karol, Hänzelmann, Sonja, Fazio, Grazia, Songia, Simona, Langerak, Anton W., Darzentas, Nikos

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Minimal residual disease assessment by multiparameter flow cytometry in transplant-eligible myeloma in the EMN02/HOVON 95 MM trial von Oliva, Stefania, Bruinink, Davine Hofste op, Rihova, Lucie, D’Agostino, Mattia, Pantani, Lucia, Capra, Andrea, van der Holt, Bronno, Troia, Rossella, Petrucci, Maria Teresa, Villanova, Tania, Vsianska, Pavla, Jugooa, Romana, Brandt-Hagens, Claudia, Gilestro, Milena, Offidani, Massimo, Ribolla, Rossella, Galli, Monica, Hajek, Roman, Gay, Francesca, Cavo, Michele, Omedé, Paola, van der Velden, Vincent H. J., Boccadoro, Mario, Sonneveld, Pieter

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Identification of distinct prognostic subgroups in low- and intermediate-1–risk myelodysplastic syndromes by flow cytometry von van de Loosdrecht, Arjan A., Westers, Theresia M., Westra, August H., Dräger, Angelika M., van der Velden, Vincent H.J., Ossenkoppele, Gert J.

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High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia von Luesink, Maaike, Hollink, Iris H.I.M., van der Velden, Vincent H.J., Knops, Ruth H.J.N., Boezeman, Jan B.M., de Haas, Valérie, Trka, Jan, Baruchel, Andre, Reinhardt, Dirk, van der Reijden, Bert A., van den Heuvel-Eibrink, Marry M., Zwaan, C. Michel, Jansen, Joop H.

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CD34+CD38− leukemic stem cell frequency to predict outcome in acute myeloid leukemia von Zeijlemaker, Wendelien, Grob, Tim, Meijer, Rosa, Hanekamp, Diana, Kelder, Angèle, Carbaat-Ham, Jannemieke C., Oussoren-Brockhoff, Yvonne J. M., Snel, Alexander N., Veldhuizen, Dennis, Scholten, Willemijn J., Maertens, Johan, Breems, Dimitri A., Pabst, Thomas, Manz, Markus G., van der Velden, Vincent H. J., Slomp, Jennichjen, Preijers, Frank, Cloos, Jacqueline, van de Loosdrecht, Arjan A., Löwenberg, Bob, Valk, Peter J. M., Jongen-Lavrencic, Mojca, Ossenkoppele, Gert J., Schuurhuis, Gerrit J.

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A phase 1 study of inotuzumab ozogamicin in pediatric relapsed/refractory acute lymphoblastic leukemia (ITCC-059 study) von Brivio, Erica, Locatelli, Franco, Lopez-Yurda, Marta, Malone, Andrea, Díaz-de-Heredia, Cristina, Bielorai, Bella, Rossig, Claudia, van der Velden, Vincent H.J., Ammerlaan, Anneke C.J., Thano, Adriana, van der Sluis, Inge M., den Boer, Monique L., Chen, Ying, Sleight, Barbara, Brethon, Benoit, Nysom, Karsten, Sramkova, Lucie, Øra, Ingrid, Vinti, Luciana, Chen-Santel, Christiane, Zwaan, Christian Michel

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Real-Time Quantitative Polymerase Chain Reaction Detection of Minimal Residual Disease by Standardized WT1 Assay to Enhance Risk Stratification in Acute Myeloid Leukemia: A Europea... von CILLONI, Daniela, RENNEVILLE, Aline, IZZO, Barbara, NOMDEDEU, Josep, VAN DER HEIJDEN, Adrian, VAN DER REIJDEN, BertA, JANSEN, Joop H, VAN DER VELDEN, Vincent H. J, OMMEN, Hans, PREUDHOMME, Claude, SAGLIO, Giuseppe, GRIMWADE, David, HERMITTE, Fabienne, HILLS, Robert K, DALY, Sarah, JOVANOVIC, Jelena V, GOTTARDI, Enrico, FAVA, Milena, SCHNITTGER, Susanne, WEISS, Tamara

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Inotuzumab ozogamicin as single agent in pediatric patients with relapsed and refractory acute lymphoblastic leukemia: results from a phase II trial von Pennesi, Edoardo, Michels, Naomi, Brivio, Erica, van der Velden, Vincent H. J., Jiang, Yilin, Thano, Adriana, Ammerlaan, Anneke J. C., Boer, Judith M., Beverloo, H. Berna, Sleight, Barbara, Chen, Ying, Vormoor-Bürger, Britta, Rives, Susana, Bielorai, Bella, Rössig, Claudia, Petit, Arnaud, Rizzari, Carmelo, Engstler, Gernot, Starý, Jan, Bautista Sirvent, Francisco J., Chen-Santel, Christiane, Bruno, Benedicte, Bertrand, Yves, Rialland, Fanny, Plat, Geneviève, Reinhardt, Dirk, Vinti, Luciana, Von Stackelberg, Arend, Locatelli, Franco, Zwaan, Christian M.

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Dysregulation of Small Nucleolar RNAs in B-Cell Malignancies von Verbeek, Martijn W. C., Erkeland, Stefan J., van der Velden, Vincent H. J.

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Are measurable residual disease results after consolidation therapy useful in children with acute lymphoblastic leukemia? von Stutterheim, Janine, van der Waarden, Rachella, de Groot-Kruseman, Hester A., Sonneveld, Edwin, de Haas, Valérie, Dandis, Rana, van der Schoot, C. Ellen, van der Velden, Vincent H. J., Pieters, Rob

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The gray area of RQ-PCR-based measurable residual disease: subdividing the “positive, below quantitative range” category von Kotrova, Michaela, Fronkova, Eva, Svaton, Michael, Drandi, Daniela, Schön, Felix, Hoogeveen, Patricia, Hancock, Jeremy, Skotnicova, Aneta, Schilhabel, Anke, Eckert, Cornelia, Clappier, Emmanuelle, Cazzaniga, Gianni, Schäfer, Beat W., van Dongen, Jacques J. M., Ritgen, Matthias, Pott, Christiane, van der Velden, Vincent H. J., Trka, Jan, Brüggemann, Monika

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Mutational mechanisms in multiply relapsed pediatric acute lymphoblastic leukemia von van der Ham, Cédric G., Suurenbroek, Lianne C., Kleisman, Michelle M., Antić, Željko, Lelieveld, Stefan H., Yeong, Marley, Westera, Liset, Sonneveld, Edwin, Hoogerbrugge, Peter M., van der Velden, Vincent H. J., van Leeuwen, Frank N., Kuiper, Roland P.

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CD123 expression levels in 846 acute leukemia patients based on standardized immunophenotyping von Bras, Anne E., Haas, Valerie, Stigt, Arthur, Jongen‐Lavrencic, Mojca, Beverloo, H. Berna, Marvelde, Jeroen G., Zwaan, C. Michel, Dongen, Jacques J.M., Leusen, Jeanette H.W., Velden, Vincent H.J.

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Truncated CSF3 receptors induce pro‐inflammatory responses in severe congenital neutropenia von Olofsen, Patricia A., Bosch, Dennis A., Looper, Hans W. J., Strien, Paulina M. H., Hoogenboezem, Remco M., Roovers, Onno, Velden, Vincent H. J., Bindels, Eric M. J., De Pater, Emma M., Touw, Ivo P.

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