RM-493, a Melanocortin-4 Receptor (MC4R) Agonist, Increases Resting Energy Expenditure in Obese Individuals von Chen, Kong Y, Muniyappa, Ranganath, Abel, Brent S, Mullins, Katherine P, Staker, Pamela, Brychta, Robert J, Zhao, Xiongce, Ring, Michael, Psota, Tricia L, Cone, Roger D, Panaro, Brandon L, Gottesdiener, Keith M, Van der Ploeg, Lex H.T, Reitman, Marc L, Skarulis, Monica C

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Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia von Berbée, Jimmy F.P, Mol, Isabel M, Milne, Ginger L, Pollock, Erik, Hoeke, Geerte, Lütjohann, Dieter, Monaco, Claudia, Rensen, Patrick C.N, van der Ploeg, Lex H.T, Shchepinov, Mikhail S

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Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency von Collet, Tinh-Hai, Dubern, Béatrice, Mokrosinski, Jacek, Connors, Hillori, Keogh, Julia M., Mendes de Oliveira, Edson, Henning, Elana, Poitou-Bernert, Christine, Oppert, Jean-Michel, Tounian, Patrick, Marchelli, Florence, Alili, Rohia, Le Beyec, Johanne, Pépin, Dominique, Lacorte, Jean-Marc, Gottesdiener, Andrew, Bounds, Rebecca, Sharma, Shubh, Folster, Cathy, Henderson, Bart, O'Rahilly, Stephen, Stoner, Elizabeth, Gottesdiener, Keith, Panaro, Brandon L., Cone, Roger D., Clément, Karine, Farooqi, I. Sadaf, Van der Ploeg, Lex H.T.

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Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation von Sharma, Shubh, Garfield, Alastair S, Shah, Bhavik, Kleyn, Patrick, Ichetovkin, Ilia, Moeller, Ida Hatoum, Mowrey, William R, Van der Ploeg, Lex H T

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Orphan G-protein-coupled receptors and natural ligand discovery von Howard, Andrew D, McAllister, George, Feighner, Scott D, Liu, Qingyun, Nargund, Ravi P, Van der Ploeg, Lex H.T, Patchett, Arthur A

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Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells von RAO, Sudhir S, O'NEIL, Jennifer, VAN DER PLOEG, Lex H. T, CARROLL, Pamela M, DRAETTA, Giulio F, LOOK, A. Thomas, STACK, Peter R, WINTER, Christopher G, LIBERATOR, Cole D, HARDWICK, James S, XUDONG DAI, ZHANG, Theresa, TYMINSKI, Edyta, JING YUAN, KOHL, Nancy E, RICHON, Victoria M

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Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity von Jacques, Vincent, Bolze, Sébastien, Hallakou‐Bozec, Sophie, Czarnik, Anthony W., Divakaruni, Ajit S., Fouqueray, Pascale, Murphy, Anne N., Van der Ploeg, Lex H.T., DeWitt, Sheila

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Molecular cloning and characterization of a new receptor for galanin von Howard, Andrew D, Tan, Carina, Shiao, Lin-Lin, Palyha, Oksana C, McKee, Karen Kulju, Weinberg, David H, Feighner, Scott D, Cascieri, Margaret A, Smith, Roy G, Van Der Ploeg, Lex H.T, Sullivan, Kathleen A

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Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass von Van der Ploeg, Lex H.T, Chen, Airu S, Marsh, Donald J, Trumbauer, Myrna E, Frazier, Easter G, Guan, Xiao-Ming, Yu, Hong, Rosenblum, Charles I, Vongs, Aurawan, Feng, Yue, Cao, Linhai, Metzger, Joseph M, Strack, Alison M, Camacho, Ramon E, Mellin, Theodore N, Nunes, Christian N, Min, William, Fisher, Jill, Gopal-Truter, Shobhna, MacIntyre, D. Euan, Chen, Howard Y

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Differential expression of mRNA for leptin receptor isoforms in the rat brain von Guan, Xiao-Ming, Hess, J.Fred, Yu, Hong, Hey, Patricia J, van der Ploeg, Lex H.T

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Melanin-Concentrating Hormone Receptor Subtypes 1 and 2: Species-Specific Gene Expression von Tan, Carina P., Sano, Hideki, Iwaasa, Hisashi, Pan, Jie, Sailer, Andreas W., Hreniuk, Donna L., Feighner, Scott D., Palyha, Oksana C., Pong, Sheng-Shung, Figueroa, David J., Austin, Christopher P., Jiang, Michael M., Yu, Hong, Ito, Junko, Ito, Makoto, Ito, Masahiko, Guan, Xiao Ming, MacNeil, Douglas J., Kanatani, Akio, Van der Ploeg, Lex H.T., Howard, Andrew D.

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Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats von Shearman, Lauren P., Camacho, Ramon E., Sloan Stribling, D., Zhou, Dan, Bednarek, Maria A., Hreniuk, Donna L., Feighner, Scott D., Tan, Carina P., Howard, Andrew D., Van der Ploeg, Lex H.T., MacIntyre, D.Euan, Hickey, Gerard J., Strack, Alison M.

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Distribution of neuromedin U receptor subtype 2 mRNA in the rat brain von Guan, Xiao-Ming, Yu, Hong, Jiang, Qingping, Van der Ploeg, Lex H.T, Liu, Qinyun

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Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment von Ayers, Kristin L, Glicksberg, Benjamin S, Garfield, Alastair S, Longerich, Simonne, White, Joseph A, Yang, Pengwei, Du, Lei, Chittenden, Thomas W, Gulcher, Jeffery R, Roy, Sophie, Fiedorek, Fred, Gottesdiener, Keith, Cohen, Sarah, North, Kari E, Schadt, Eric E, Li, Shuyu D, Chen, Rong, Van der Ploeg, Lex H T

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Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs von Jacques, Vincent, Czarnik, Anthony W., Judge, Thomas M., Van der Ploeg, Lex H. T., DeWitt, Sheila H.

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The Pentapeptide RM-131 Promotes Food Intake and Adiposity in Wildtype Mice but Not in Mice Lacking the Ghrelin Receptor von Fischer, Katrin, Finan, Brian, Clemmensen, Christoffer, van der Ploeg, Lex H T, Tschöp, Matthias H, Müller, Timo D

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Cloning and Characterization of Two Human G Protein-Coupled Receptor Genes (GPR38 and GPR39) Related to the Growth Hormone Secretagogue and Neurotensin Receptors von McKee, Karen Kulju, Tan, Carina P., Palyha, Oksana C., Liu, Jim, Feighner, Scott D., Hreniuk, Donna L., Smith, Roy G., Howard, Andrew D., Van der Ploeg, Lex H.T.

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Role of the melanocortin-4 receptor in metabolic rate and food intake in mice von CHEN, A. S, METZGER, J. M, CAMACHO, R. E, STRACK, A. M, MELLIN, T. N, MACINTYRE, D. E, CHEN, H. Y, VAN DER PLOEG, L. H. T, TRUMBAUER, M. E, GUAN, X.-M, HONG YU, FRAZIER, E. G, MARSH, D. J, FORREST, M. J, GOPAL-TRUTER, S, FISHER, J

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Exploring the site of anorectic action of peripherally administered synthetic melanocortin peptide MT-II in rats von Trivedi, Prashant, Jiang, Michael, Tamvakopoulos, Constantin C, Shen, Xiaolan, Yu, Hong, Mock, Steven, Fenyk-Melody, Judy, Van der Ploeg, Lex H.T, Guan, Xiao-Ming

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ART (Protein Product of Agouti-Related Transcript) as an Antagonist of MC-3 and MC-4 Receptors von Fong, Tung Ming, Mao, Cheri, MacNeil, Tanya, Kalyani, Rubana, Smith, Tim, Weinberg, David, Tota, Michael R., Van der Ploeg, Lex H.T.

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