MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins von Calvo, Sarah E, Clauser, Karl R, Mootha, Vamsi K

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The molecular era of the mitochondrial calcium uniporter von Kamer, Kimberli J., Mootha, Vamsi K.

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Proteomic Mapping of the Human Mitochondrial Intermembrane Space in Live Cells via Ratiometric APEX Tagging von Hung, Victoria, Zou, Peng, Rhee, Hyun-Woo, Udeshi, Namrata D., Cracan, Valentin, Svinkina, Tanya, Carr, Steven A., Mootha, Vamsi K., Ting, Alice Y.

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Complementation of mitochondrial electron transport chain by manipulation of the NAD⁺/NADH ratio von Titov, Denis V., Cracan, Valentin, Goodman, Russell P., Peng, Jun, Grabarek, Zenon, Mootha, Vamsi K.

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A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing von Mok, Beverly Y., de Moraes, Marcos H., Zeng, Jun, Bosch, Dustin E., Kotrys, Anna V., Raguram, Aditya, Hsu, FoSheng, Radey, Matthew C., Peterson, S. Brook, Mootha, Vamsi K., Mougous, Joseph D., Liu, David R.

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Directed evolution of APEX2 for electron microscopy and proximity labeling von Lam, Stephanie S, Martell, Jeffrey D, Kamer, Kimberli J, Deerinck, Thomas J, Ellisman, Mark H, Mootha, Vamsi K, Ting, Alice Y

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MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling von Plovanich, Molly, Bogorad, Roman L, Sancak, Yasemin, Kamer, Kimberli J, Strittmatter, Laura, Li, Andrew A, Girgis, Hany S, Kuchimanchi, Satya, De Groot, Jack, Speciner, Lauren, Taneja, Nathan, Oshea, Jonathan, Koteliansky, Victor, Mootha, Vamsi K

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Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism von Jain, Isha H., Calvo, Sarah E., Markhard, Andrew L., Skinner, Owen S., To, Tsz-Leung, Ast, Tslil, Mootha, Vamsi K.

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MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter von Csordás, György, Golenár, Tünde, Seifert, Erin L., Kamer, Kimberli J., Sancak, Yasemin, Perocchi, Fabiana, Moffat, Cynthia, Weaver, David, Perez, Sergio de la Fuente, Bogorad, Roman, Koteliansky, Victor, Adijanto, Jeffrey, Mootha, Vamsi K., Hajnóczky, György

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The mitochondrial proteome and human disease von Calvo, Sarah E, Mootha, Vamsi K

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TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis von Ye, Li, Kleiner, Sandra, Wu, Jun, Sah, Rajan, Gupta, Rana K, Banks, Alexander S, Cohen, Paul, Khandekar, Melin J, Boström, Pontus, Mepani, Rina J, Laznik, Dina, Kamenecka, Theodore M, Song, Xinyi, Liedtke, Wolfgang, Mootha, Vamsi K, Puigserver, Pere, Griffin, Patrick R, Clapham, David E, Spiegelman, Bruce M

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Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging von Rhee, Hyun-Woo, Zou, Peng, Udeshi, Namrata D., Martell, Jeffrey D., Mootha, Vamsi K., Carr, Steven A., Ting, Alice Y.

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Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer von Nilsson, Roland, Jain, Mohit, Madhusudhan, Nikhil, Sheppard, Nina Gustafsson, Strittmatter, Laura, Kampf, Caroline, Huang, Jenny, Asplund, Anna, Mootha, Vamsi K.

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Architecture of the mitochondrial calcium uniporter von Oxenoid, Kirill, Dong, Ying, Cao, Chan, Cui, Tanxing, Sancak, Yasemin, Markhard, Andrew L., Grabarek, Zenon, Kong, Liangliang, Liu, Zhijun, Ouyang, Bo, Cong, Yao, Mootha, Vamsi K., Chou, James J.

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Hypoxia extends lifespan and neurological function in a mouse model of aging von Rogers, Robert S, Wang, Hong, Durham, Timothy J, Stefely, Jonathan A, Owiti, Norah A, Markhard, Andrew L, Sandler, Lev, To, Tsz-Leung, Mootha, Vamsi K

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A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation von Arroyo, Jason D., Jourdain, Alexis A., Calvo, Sarah E., Ballarano, Carmine A., Doench, John G., Root, David E., Mootha, Vamsi K.

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Hypoxia as a therapy for mitochondrial disease von Jain, Isha H., Zazzeron, Luca, Goli, Rahul, Alexa, Kristen, Schatzman-Bone, Stephanie, Dhillon, Harveen, Goldberger, Olga, Peng, Jun, Shalem, Ophir, Sanjana, Neville E., Zhang, Feng, Goessling, Wolfram, Zapol, Warren M., Mootha, Vamsi K.

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IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins von Dai, Ning, Zhao, Liping, Wrighting, Diedra, Krämer, Dana, Majithia, Amit, Wang, Yanqun, Cracan, Valentin, Borges-Rivera, Diego, Mootha, Vamsi K., Nahrendorf, Matthias, Thorburn, David R., Minichiello, Liliana, Altshuler, David, Avruch, Joseph

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Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation von Hung, Victoria, Lam, Stephanie S, Udeshi, Namrata D, Svinkina, Tanya, Guzman, Gaelen, Mootha, Vamsi K, Carr, Steven A, Ting, Alice Y

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Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation von Jain, Mohit, Nilsson, Roland, Sharma, Sonia, Madhusudhan, Nikhil, Kitami, Toshimori, Souza, Amanda L., Kafri, Ran, Kirschner, Marc W., Clish, Clary B., Mootha, Vamsi K.

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