Fialuridine induces acute liver failure in chimeric TK-NOG mice: a model for detecting hepatic drug toxicity prior to human testing von Xu, Dan, Nishimura, Toshi, Nishimura, Sachiko, Zhang, Haili, Zheng, Ming, Guo, Ying-Ying, Masek, Marylin, Michie, Sara A, Glenn, Jeffrey, Peltz, Gary

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Inflammatory manifestations of experimental lymphatic insufficiency von Tabibiazar, Raymond, Cheung, Lauren, Han, Jennifer, Swanson, Jeffrey, Beilhack, Andreas, An, Andrew, Dadras, Soheil S, Rockson, Ned, Joshi, Smita, Wagner, Roger, Rockson, Stanley G

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Methods of blinding in reports of randomized controlled trials assessing pharmacologic treatments: a systematic review von Boutron, Isabelle, Estellat, Candice, Guittet, Lydia, Dechartres, Agnes, Sackett, David L, Hróbjartsson, Asbjørn, Ravaud, Philippe

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Hope Groups: a protocol for a cluster randomized controlled trial of psychosocial, mental health, and parenting support groups for Ukrainian caregivers during war and conflict von Tucker, S, Baldonado, N, Ruina, O, Ratmann, O, Flaxman, S, Bryn, L, Lachman, J, Taradaika, E, Melendez-Torres, GJ, Vallance, I, Goldman, P, Cluver, L, Hillis, S

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Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury von Bagshaw, Sean M, Wald, Ron, Adhikari, Neill K J, Bellomo, Rinaldo, da Costa, Bruno R, Dreyfuss, Didier, Du, Bin, Gallagher, Martin P, Gaudry, Stéphane, Hoste, Eric A, Lamontagne, François, Joannidis, Michael, Landoni, Giovanni, Liu, Kathleen D, McAuley, Daniel F, McGuinness, Shay P, Neyra, Javier A, Nichol, Alistair D, Ostermann, Marlies, Palevsky, Paul M, Pettilä, Ville, Quenot, Jean-Pierre, Qiu, Haibo, Rochwerg, Bram, Schneider, Antoine G, Smith, Orla M, Thomé, Fernando, Thorpe, Kevin E, Vaara, Suvi, Weir, Matthew, Wang, Amanda Y, Young, Paul, Zarbock, Alexander

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Increased Intestinal Permeability Is Associated With Later Development of Crohn’s Disease von Turpin, Williams, Lee, Sun-Ho, Raygoza Garay, Juan Antonio, Madsen, Karen L., Meddings, Jonathan B., Bedrani, Larbi, Power, Namita, Espin-Garcia, Osvaldo, Xu, Wei, Smith, Michelle I., Griffiths, Anne M., Moayyedi, Paul, Turner, Dan, Seidman, Ernest G., Steinhart, A. Hillary, Marshall, John K., Jacobson, Kevan, Mack, David, Huynh, Hien, Bernstein, Charles N., Paterson, Andrew D., Abreu, Maria, Beck, Paul, Bernstein, Charles, Croitoru, Kenneth, Dieleman, Leo, Feagan, Brian, Griffiths, Anne, Guttman, David, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O., Madsen, Karen, Marshall, John, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark, Snapper, Scott, Stadnyk, Andy, Steinhart, Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien, Hyams, Jeff, Mack, David, McGrath, Jerry, Otley, Anthony, Panancionne, Remo, Baldassano, Robert, Griffiths, Anne M., Hedin, Charlotte, Hussey, Seamus, Hyams, Hien, Keljo, David, Kevans, David, Lees, Charlie, Murthy, Sanjay, Panaccione, Remo, Parekh, Nimisha, Plamondon, Sophie, Radford-Smith, Graham, Rosh, Joel, Rubin, David, Schultz, Michael, Siegel, Corey, Turner, Dan, Croitoru, Kenneth

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Association of host genome with intestinal microbial composition in a large healthy cohort von Turpin, Williams, Espin-Garcia, Osvaldo, Xu, Wei, Silverberg, Mark S, Kevans, David, Smith, Michelle I, Guttman, David S, Griffiths, Anne, Panaccione, Remo, Otley, Anthony, Xu, Lizhen, Shestopaloff, Konstantin, Moreno-Hagelsieb, Gabriel, Paterson, Andrew D, Croitoru, Kenneth

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Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis von Galipeau, Heather J., Caminero, Alberto, Turpin, Williams, Bermudez-Brito, Miriam, Santiago, Alba, Libertucci, Josie, Constante, Marco, Raygoza Garay, Juan Antonio, Rueda, Gaston, Armstrong, Sarah, Clarizio, Alex, Smith, Michelle I., Surette, Michael G., Bercik, Premysl, Beck, Paul, Bernstein, Charles, Croitoru, Kenneth, Dieleman, Leo, Feagan, Brian, Griffiths, Anne, Guttman, David, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O., Madsen, Karen, Marshall, John, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark, Snapper, Scott, Stadnyk, Andy, Steinhart, Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien, Hyams, Jeff, Mack, David, McGrath, Jerry, Otley, Anthony, Panancionne, Remo, Croitoru, Kenneth, Verdu, Elena F.

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Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial von Nichol, Alistair, Prof, French, Craig, Dr, Little, Lorraine, MBioethics, Haddad, Samir, MD, Presneill, Jeffrey, PhD, Arabi, Yaseen, MD, Bailey, Michael, PhD, Cooper, D James, Prof, Duranteau, Jacques, Prof, Huet, Olivier, Prof, Mak, Anne, BScPharm, McArthur, Colin, MBChB, Pettilä, Ville, Prof, Skrifvars, Markus, PhD, Vallance, Shirley, MPH, Varma, Dinesh, MBBS, Wills, Judy, DMU, Bellomo, Rinaldo, Prof

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Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives von Raygoza Garay, Juan Antonio, Turpin, Williams, Lee, Sun-Ho, Smith, Michelle I., Goethel, Ashleigh, Griffiths, Anne M., Moayyedi, Paul, Espin-Garcia, Osvaldo, Abreu, Maria, Aumais, Guy L., Bernstein, Charles N., Biron, Irit A., Cino, Maria, Deslandres, Colette, Dotan, Iris, El-Matary, Wael, Feagan, Brian, Guttman, David S., Huynh, Hien, Dieleman, Levinus A., Hyams, Jeffrey S., Jacobson, Kevan, Mack, David, Marshall, John K., Otley, Anthony, Panaccione, Remo, Ropeleski, Mark, Silverberg, Mark S., Steinhart, A. Hillary, Turner, Dan, Yerushalmi, Baruch, Paterson, Andrew D., Xu, Wei, Abreu, Maria, Beck, Paul, Bernstein, Charles, Croitoru, Kenneth, Dieleman, Levinus A., Feagan, Brian, Griffiths, Anne, Guttman, David, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O., Madsen, Karen, Marshall, John, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark, Snapper, Scott, Stadnyk, Andy, Steinhart, Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien, Hyams, Jeffrey S., Mack, David, McGrath, Jerry, Otley, Anthony, Panancionne, Remo, Croitoru, Kenneth

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Trial of Early, Goal-Directed Resuscitation for Septic Shock von Mouncey, Paul R, Osborn, Tiffany M, Power, G. Sarah, Harrison, David A, Sadique, M. Zia, Grieve, Richard D, Jahan, Rahi, Harvey, Sheila E, Bell, Derek, Bion, Julian F, Coats, Timothy J, Singer, Mervyn, Young, J. Duncan, Rowan, Kathryn M

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Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study von Glasbey, James C, Nepogodiev, Dmitri, Simoes, Joana F F, Omar, Omar, Li, Elizabeth, Venn, Mary L, Pgdme, Abou Chaar, Mohammad K, Capizzi, Vita, Chaudhry, Daoud, Desai, Anant, Edwards, Jonathan G, Evans, Jonathan P, Fiore, Marco, Videria, Jose Flavio, Ford, Samuel J, Ganly, Ian, Griffiths, Ewen A, Gujjuri, Rohan R, Kolias, Angelos G, Kaafarani, Haytham M A, Minaya-Bravo, Ana, McKay, Siobhan C, Mohan, Helen M, Roberts, Keith J, San Miguel-Méndez, Carlos, Pockney, Peter, Shaw, Richard, Smart, Neil J, Stewart, Grant D, Sundar Mrcog, Sudha, Vidya, Raghavan, Bhangu, Aneel A

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Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation von Turpin, Williams, Dong, Mei, Sasson, Gila, Raygoza Garay, Juan Antonio, Espin-Garcia, Osvaldo, Lee, Sun-Ho, Neustaeter, Anna, Smith, Michelle I., Leibovitzh, Haim, Guttman, David S., Goethel, Ashleigh, Griffiths, Anne M., Huynh, Hien Q., Dieleman, Levinus A., Panaccione, Remo, Steinhart, A. Hillary, Silverberg, Mark S., Aumais, Guy, Jacobson, Kevan, Mack, David, Murthy, Sanjay K., Marshall, John K., Bernstein, Charles N., Abreu, Maria T., Moayyedi, Paul, Paterson, Andrew D., Abreu, Maria, Beck, Paul, Bernstein, Charles, Croitoru, Kenneth, Dieleman, Leo, Feagan, Brian, Griffiths, Anne, Guttman, David, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O., Madsen, Karen, Marshall, John, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark, Snapper, Scott, Stadnyk, Andy, Steinhart, Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien, Hyams, Jeff, Mack, David, McGrath, Jerry, Otley, Anthony, Panancionne, Remo, Baldassano, Robert, Griffiths, Anne M., Hedin, Charlotte, Hussey, Seamus, Hyams, Hien, Keljo, David, Kevans, David, Lees, Charlie, Murthy, Sanjay, Panaccione, Remo, Parekh, Nimisha, Plamondon, Sophie, Radford-Smith, Graham, Rosh, Joel, Rubin, David, Schultz, Michael, Siegel, Corey, Xu, Wei, Croitoru, Kenneth

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Prehospital Tranexamic Acid for Severe Trauma von Gruen, Russell L, Mitra, Biswadev, Bernard, Stephen A, McArthur, Colin J, Burns, Brian, Gantner, Dashiell C, Maegele, Marc, Cameron, Peter A, Dicker, Bridget, Forbes, Andrew B, Hurford, Sally, Martin, Catherine A, Mazur, Stefan M, Medcalf, Robert L, Murray, Lynnette J, Myles, Paul S, Ng, Sze J, Pitt, Veronica, Rashford, Stephen, Reade, Michael C, Swain, Andrew H, Trapani, Tony, Young, Paul J

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Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial von Cooper, D. James, Nichol, Alistair D, Bailey, Michael, Bernard, Stephen, Cameron, Peter A, Pili-Floury, Sébastien, Forbes, Andrew, Gantner, Dashiell, Higgins, Alisa M, Huet, Olivier, Kasza, Jessica, Murray, Lynne, Newby, Lynette, Presneill, Jeffrey J, Rashford, Stephen, Rosenfeld, Jeffrey V, Stephenson, Michael, Vallance, Shirley, Varma, Dinesh, Webb, Steven A. R, Trapani, Tony, McArthur, Colin

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Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial von Reade, Michael C, Eastwood, Glenn M, Bellomo, Rinaldo, Bailey, Michael, Bersten, Andrew, Cheung, Benjamin, Davies, Andrew, Delaney, Anthony, Ghosh, Angaj, van Haren, Frank, Harley, Nerina, Knight, David, McGuiness, Shay, Mulder, John, O’Donoghue, Steve, Simpson, Nicholas, Young, Paul

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Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI von Yuh, Esther L, Jain, Sonia, Sun, Xiaoying, Pisica, Dana, Harris, Mark H, Taylor, Sabrina R, Markowitz, Amy J, Mukherjee, Pratik, Verheyden, Jan, Giacino, Joseph T, Levin, Harvey S, McCrea, Michael, Stein, Murray B, Temkin, Nancy R, Diaz-Arrastia, Ramon, Robertson, Claudia S, Lingsma, Hester F, Okonkwo, David O, Maas, Andrew I.R, Manley, Geoffrey T, Adeoye, Opeolu, Badjatia, Neeraj, Boase, Kim, Bodien, Yelena, Corrigan, John D, Crawford, Karen, Dikmen, Sureyya, Duhaime, Ann-Christine, Ellenbogen, Richard, Feeser, V. Ramana, Ferguson, Adam R, Foreman, Brandon, Gardner, Raquel, Gaudette, Etienne, Gonzalez, Luis, Gopinath, Shankar, Gullapalli, Rao, Hemphill, J. Claude, Hotz, Gillian, Keene, C. Dirk, Kramer, Joel, Kreitzer, Natalie, Lindsell, Chris, Machamer, Joan, Madden, Christopher, Martin, Alastair, McAllister, Thomas, Merchant, Randall, Nelson, Lindsay, Ngwenya, Laura B, Noel, Florence, Nolan, Amber, Palacios, Eva, Perl, Daniel, Rabinowitz, Miri, Rosand, Jonathan, Sander, Angelle, Satris, Gabriella, Schnyer, David, Seabury, Seth, Toga, Arthur, Valadka, Alex, Vassar, Mary, Zafonte, Ross

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Decompressive Craniectomy in Diffuse Traumatic Brain Injury von Cooper, D. James, Rosenfeld, Jeffrey V, Murray, Lynnette, Arabi, Yaseen M, Davies, Andrew R, D'Urso, Paul, Kossmann, Thomas, Ponsford, Jennie, Seppelt, Ian, Reilly, Peter, Wolfe, Rory

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Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn’s disease highlight earliest events of pathogenesis von Leibovitzh, Haim, Lee, Sun-Ho, Raygoza Garay, Juan Antonio, Espin-Garcia, Osvaldo, Xue, Mingyue, Neustaeter, Anna, Goethel, Ashleigh, Huynh, Hien Q, Griffiths, Anne M, Turner, Dan, Madsen, Karen L, Moayyedi, Paul, Steinhart, A Hillary, Silverberg, Mark S, Deslandres, Colette, Bitton, Alain, Mack, David R, Jacobson, Kevan, Cino, Maria, Aumais, Guy, Bernstein, Charles N, Panaccione, Remo, Weiss, Batia, Halfvarson, Jonas, Xu, Wei, Turpin, Williams, Croitoru, Kenneth, Abreu, Maria, Beck, Paul, Bernstein, Charles N, Croitoru, Kenneth, Dieleman, Levinus A, Feagan, Brian, Griffiths, Anne M, Guttman, David S, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O, Madsen, Karen L, Marshall, John K, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark S, Snapper, Scott, Stadnyk, Andy, Steinhart, A Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien Q, Hyams, Jeff, Mack, David R, McGrath, Jerry, Otley, Anthony, Panaccione, Remo

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Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis von Livanos, Alexandra E., Dunn, Alexandra, Fischer, Jeremy, Ungaro, Ryan C., Turpin, Williams, Lee, Sun-Ho, Rui, Shumin, Del Valle, Diane Marie, Jougon, Julia J., Martinez-Delgado, Gustavo, Riddle, Mark S., Murray, Joseph A., Laird, Renee M., Torres, Joana, Agrawal, Manasi, Magee, Jared S., Dervieux, Thierry, Gnjatic, Sacha, Sheppard, Dean, Sands, Bruce E., Porter, Chad K., Croitoru, Kenneth, Petralia, Francesca, Abreu, Maria, Beck, Paul, Bernstein, Charles, Croitoru, Kenneth, Dieleman, Leo, Feagan, Brian, Griffiths, Anne, Guttman, David, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O., Madsen, Karen, Marshall, John, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark, Snapper, Scott, Stadnyk, Andy, Steinhart, Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien, Hyams, Jeff, Mack, David, McGrath, Jerry, Otley, Anthony, Panancionne, Remo, Shapiro, Jason, Shah, Samir, Leleiko, Neal S., Colombel, Jean-Frederic, Mehandru, Saurabh

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