signeR: an empirical Bayesian approach to mutational signature discovery von Rosales, Rafael A, Drummond, Rodrigo D, Valieris, Renan, Dias-Neto, Emmanuel, da Silva, Israel T

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Relating mutational signature exposures to clinical data in cancers via signeR 2.0 von Drummond, Rodrigo D, Defelicibus, Alexandre, Meyenberg, Mathilde, Valieris, Renan, Dias-Neto, Emmanuel, Rosales, Rafael A, da Silva, Israel Tojal

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Weakly-supervised deep learning models enable HER2-low prediction from H &E stained slides von Valieris, Renan, Martins, Luan, Defelicibus, Alexandre, Bueno, Adriana Passos, de Toledo Osorio, Cynthia Aparecida Bueno, Carraro, Dirce, Dias-Neto, Emmanuel, Rosales, Rafael A, de Figueiredo, Jose Marcio Barros, Silva, Israel Tojal da

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Family-based whole-exome sequencing identifies rare variants potentially related to cutaneous melanoma predisposition in Brazilian melanoma-prone families von Fidalgo, Felipe, Torrezan, Giovana Tardin, Sá, Bianca Costa Soares de, Barros, Bruna Durães de Figueiredo, Moredo, Luciana Facure, Valieris, Renan, de Souza, Sandro J, Duprat, João Pereira, Krepischi, Ana Cristina Victorino, Carraro, Dirce Maria

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Influence of BRCA1 Germline Mutations in the Somatic Mutational Burden of Triple-Negative Breast Cancer von Ferreira, Elisa Napolitano, Brianese, Rafael Canfield, de Almeida, Renan Valieris Bueno, Drummond, Rodrigo Duarte, de Souza, Jorge Estefano, da Silva, Israel Tojal, de Souza, Sandro José, Carraro, Dirce Maria

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Insights Into the Somatic Mutation Burden of Hepatoblastomas From Brazilian Patients von Marques Aguiar, Talita Ferreira, Rivas, Maria Prates, Costa, Silvia, Maschietto, Mariana, Rodrigues, Tatiane, de Barros, Juliana Sobral, Barbosa, Anne Caroline, Valieris, Renan, Fernandes, Gustavo R., Bertola, Debora R., Cypriano, Monica, Caminada de Toledo, Silvia Regina, Major, Angela, Tojal, Israel, de Pinho Apezzato, Maria Lucia, Carraro, Dirce Maria, Rosenberg, Carla, Lima da Costa, Cecilia Maria, Cunha, Isabela W., Sarabia, Stephen Frederick, Terrada, Dolores-Lopez, Victorino Krepischi, Ana Cristina

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Complex Landscape of Germline Variants in Brazilian Patients With Hereditary and Early Onset Breast Cancer von Torrezan, Giovana T, de Almeida, Fernanda G Dos Santos R, Figueiredo, Márcia C P, Barros, Bruna D de Figueiredo, de Paula, Cláudia A A, Valieris, Renan, de Souza, Jorge E S, Ramalho, Rodrigo F, da Silva, Felipe C C, Ferreira, Elisa N, de Nóbrega, Amanda F, Felicio, Paula S, Achatz, Maria I, de Souza, Sandro J, Palmero, Edenir I, Carraro, Dirce M

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A comparison between SOLiD 5500XLand Ion Torrent PGM-derived miRNA expression profiles in two breast cell lines von Branco, Gabriela Pereira, Valieris, Renan, Povoa, Lucas Venezian, Araújo, Luiza Ferreira de, Fernandes, Gustavo Ribeiro, Souza, Jorge Estefano Santana de, Amorim, Maria Galli de, Ferreira, Elisa Napolitano E, Silva, Israel Tojal da, Nunes, Diana Noronha, Dias-Neto, Emmanuel

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Exome sequencing of multiple-sclerosis patients and their unaffected first-degree relatives von Garcia-Rosa, Sheila, de Amorim, Maria Galli, Valieris, Renan, Marques, Vanessa Daccach, Lorenzi, Julio Cesar Cetrulo, Toller, Vania Balardin, do Olival, Guilherme Sciascia, da Silva Júnior, Wilson Araújo, da Silva, Israel Tojal, Barreira, Amilton Antunes, Nunes, Diana Noronha, Dias-Neto, Emmanuel

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S-score: a scoring system for the identification and prioritization of predicted cancer genes von de Souza, Jorge E S, Fonseca, André F, Valieris, Renan, Carraro, Dirce M, Wang, Jean Y J, Kolodner, Richard D, de Souza, Sandro J

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miRNAs 144-3p, 34a-5p, and 206 are a useful signature for distinguishing uterine leiomyosarcoma from other smooth muscle tumors von Schiavon, Beatriz Nunes, Carvalho, Katia Candido, Coutinho-Camillo, Cláudia Malheiros, Baiocchi, Glauco, Valieris, Renan, Drummond, Rodrigo, da Silva, Israel Tojal, De Brot, Louise, Soares, Fernando Augusto, da Cunha, Isabela Werneck

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Human dendritic cells (DCs) are derived from distinct circulating precursors that are precommitted to become CD1c+ or CD141+ DCs von Breton, Gaëlle, Zheng, Shiwei, Valieris, Renan, Tojal da Silva, Israel, Satija, Rahul, Nussenzweig, Michel C

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Bioconda: sustainable and comprehensive software distribution for the life sciences von Grüning, Björn, Dale, Ryan, Sjödin, Andreas, Chapman, Brad A., Rowe, Jillian, Tomkins-Tinch, Christopher H., Valieris, Renan, Köster, Johannes

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A mixture model for determining SARS-Cov-2 variant composition in pooled samples von Valieris, Renan, Drummond, Rodrigo D, Defelicibus, Alexandre, Dias-Neto, Emmanuel, Rosales, Rafael A, Tojal da Silva, Israel

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Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation von Cohn, Lillian B., da Silva, Israel T., Valieris, Renan, Huang, Amy S., Lorenzi, Julio C. C., Cohen, Yehuda Z., Pai, Joy A., Butler, Allison L., Caskey, Marina, Jankovic, Mila, Nussenzweig, Michel C.

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APOBEC‐mediated DNA alterations: A possible new mechanism of carcinogenesis in EBV‐positive gastric cancer von Bobrovnitchaia, Irina, Valieris, Renan, Drummond, Rodrigo D., Lima, Joao P., Freitas, Helano C., Bartelli, Thais F., Amorim, Maria G., Nunes, Diana N., Dias‐Neto, Emmanuel, Silva, Israel T.

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A total transcriptome profiling method for plasma-derived extracellular vesicles: applications for liquid biopsies von Amorim, Maria G., Valieris, Renan, Drummond, Rodrigo D., Pizzi, Melissa P., Freitas, Vanessa M., Sinigaglia-Coimbra, Rita, Calin, George A., Pasqualini, Renata, Arap, Wadih, Silva, Israel T., Dias-Neto, Emmanuel, Nunes, Diana N.

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Deep Learning Predicts Underlying Features on Pathology Images with Therapeutic Relevance for Breast and Gastric Cancer von Valieris, Renan, Amaro, Lucas, Bueno de Toledo Osorio, Cynthia Aparecida, Bueno, Adriana Passos, Rosales Mitrowsky, Rafael Andres, Carraro, Dirce Maria, Nunes, Diana Noronha, Dias-Neto, Emmanuel, da Silva, Israel Tojal

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Bioconda: sustainable and comprehensive software distribution for the life sciences von Grüning, Björn, Dale, Ryan, Sjödin, Andreas, Chapman, Brad Alan, Rowe, Jillian, Tomkins-Tinch, Christopher Holiday, Valieris, Renan, Köster, Johannes

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Abstract 3245: The interplay between patient´s features and mutational processes in tobacco related cancers von Lima, João Paulo da Silveira Nogueira, Drummond, Rodrigo Couto Duarte, Santos, Monize Nakamoto Provisor, Valieris, Renan, Mitrowsky, Rafael Andres Rosales, Lima, Vladmir Cordeiro, Nunes, Diana Noronha, Dias-Neto, Emmanuel, Silva, Israel Tojal da

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