Abstract P054: Immune determinants of the association between tumor mutational burden and immunotherapy response across cancer types von Sinha, Neelam, Sinha, Sanju, Valero, Christina, Schaffer, Alejandro A., Aldape, Kenneth, Litchfield, Kevin, Chan, Timothy A., Morris, Luc G. T., Ruppin, Eytan

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Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition von Inclan-Rico, Juan M., Ponessa, John J., Valero-Pacheco, Nuriban, Hernandez, Christina M., Sy, Chandler B., Lemenze, Alexander D., Beaulieu, Aimee M., Siracusa, Mark C.

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Genomic and Phenotypic Analysis of COVID-19-Associated Pulmonary Aspergillosis Isolates of Aspergillus fumigatus von Steenwyk, Jacob L, Mead, Matthew E, de Castro, Patrícia Alves, Valero, Clara, Damasio, André, Dos Santos, Renato A C, Labella, Abigail L, Li, Yuanning, Knowles, Sonja L, Raja, Huzefa A, Oberlies, Nicholas H, Zhou, Xiaofan, Cornely, Oliver A, Fuchs, Frieder, Koehler, Philipp, Goldman, Gustavo H, Rokas, Antonis

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Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia von Bernard-Raichon, Lucie, Venzon, Mericien, Klein, Jon, Axelrad, Jordan E., Zhang, Chenzhen, Sullivan, Alexis P., Hussey, Grant A., Casanovas-Massana, Arnau, Noval, Maria G., Valero-Jimenez, Ana M., Gago, Juan, Putzel, Gregory, Pironti, Alejandro, Wilder, Evan, Thorpe, Lorna E., Littman, Dan R., Dittmann, Meike, Stapleford, Kenneth A., Shopsin, Bo, Torres, Victor J., Ko, Albert I., Iwasaki, Akiko, Cadwell, Ken, Schluter, Jonas

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Cerebrospinal fluid viral escape in aviremic HIV-infected patients receiving antiretroviral therapy: prevalence, risk factors and neurocognitive effects von Pérez-Valero, Ignacio, Ellis, Ronald, Heaton, Robert, Deutsch, Reena, Franklin, Donald, Clifford, David B, Collier, Ann, Gelman, Benjamin, Marra, Christina, McCutchan, John Allen, Navis, Allison, Sacktor, Ned, Simpson, David, Grant, Igor, Letendre, Scott

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The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Repla... von Roberts, Jason A, Joynt, Gavin M, Lee, Anna, Choi, Gordon, Bellomo, Rinaldo, Kanji, Salmaan, Mudaliar, M Yugan, Peake, Sandra L, Stephens, Dianne, Taccone, Fabio Silvio, Ulldemolins, Marta, Valkonen, Miia Maaria, Agbeve, Julius, Baptista, João P, Bekos, Vasileios, Boidin, Clement, Brinkmann, Alexander, Buizen, Luke, Castro, Pedro, Cole, C Louise, Creteur, Jacques, De Waele, Jan J, Deans, Renae, Eastwood, Glenn M, Escobar, Leslie, Gomersall, Charles, Gresham, Rebecca, Jamal, Janattul Ain, Kluge, Stefan, König, Christina, Koulouras, Vasilios P, Lassig-Smith, Melissa, Laterre, Pierre-Francois, Lei, Katie, Leung, Patricia, Lefrant, Jean-Yves, Llauradó-Serra, Mireia, Martin-Loeches, Ignacio, Mat Nor, Mohd Basri, Ostermann, Marlies, Parker, Suzanne L, Rello, Jordi, Roberts, Darren M, Roberts, Michael S, Richards, Brent, Rodríguez, Alejandro, Roehr, Anka C, Roger, Claire, Seoane, Leonardo, Sinnollareddy, Mahipal, Sousa, Eduardo, Soy, Dolors, Spring, Anna, Starr, Therese, Thomas, Jane, Turnidge, John, Wallis, Steven C, Williams, Tricia, Wittebole, Xavier, Zikou, Xanthi T, Paul, Sanjoy K, Lipman, Jeffrey

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A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2 von Valero-González, Jessika, Leonhard-Melief, Christina, Lira-Navarrete, Erandi, Jiménez-Osés, Gonzalo, Hernández-Ruiz, Cristina, Pallarés, María Carmen, Yruela, Inmaculada, Vasudevan, Deepika, Lostao, Anabel, Corzana, Francisco, Takeuchi, Hideyuki, Haltiwanger, Robert S, Hurtado-Guerrero, Ramon

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Intrafamilial variability in SLC6A1 -related neurodevelopmental disorders von Kassabian, Benedetta, Fenger, Christina Dühring, Willems, Marjolaine, Aledo-Serrano, Angel, Linnankivi, Tarja, McDonnell, Pamela Pojomovsky, Lusk, Laina, Jepsen, Birgit Susanne, Bayat, Michael, Kattentidt, Anja, Vidal, Anna Abulí, Valero-Lopez, Gabriel, Alarcon-Martinez, Helena, Goodspeed, Kimberly, van Slegtenhorst, Marjon, Barakat, Tahsin Stefan, Møller, Rikke S, Johannesen, Katrine M, Rubboli, Guido

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A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer von Bonjer, H. Jaap, Deijen, Charlotte L, Abis, Gabor A, Cuesta, Miguel A, van der Pas, Martijn H.G.M, de Lange-de Klerk, Elly S.M, Lacy, Antonio M, Bemelman, Willem A, Andersson, John, Angenete, Eva, Rosenberg, Jacob, Fuerst, Alois, Haglind, Eva

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Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial von van der Pas, Martijn HGM, MD, Haglind, Eva, Prof, Cuesta, Miguel A, Prof, Fürst, Alois, Prof, Lacy, Antonio M, Prof, Hop, Wim CJ, PhD, Bonjer, Hendrik Jaap, Prof

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Corrigendum: Intrafamilial variability in SLC6A1-related neurodevelopmental disorders von Kassabian, Benedetta, Fenger, Christina Dühring, Willems, Marjolaine, Aledo-Serrano, Angel, Linnankivi, Tarja, McDonnell, Pamela Pojomovsky, Lusk, Laina, Jepsen, Birgit Susanne, Bayat, Michael, Kattentidt-Mouravieva, Anja A., Vidal, Anna Abulí, Valero-Lopez, Gabriel, Alarcon-Martinez, Helena, Goodspeed, Kimberly, van Slegtenhorst, Marjon, Barakat, Tahsin Stefan, Møller, Rikke S., Johannesen, Katrine M., Rubboli, Guido

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Combination of JAKi and HDACi Exerts Antiangiogenic Potential in Cutaneous T-Cell Lymphoma von Karagianni, Fani, Piperi, Christina, Valero-Diaz, Sara, Amato, Camilla, Vaque, Jose Pedro, Casar, Berta, Papadavid, Evangelia

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A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability von Temps, Carolin, Lietha, Daniel, Webb, Emily R, Li, Xue-Feng, Dawson, John C, Muir, Morwenna, Macleod, Kenneth G, Valero, Teresa, Munro, Alison F, Contreras-Montoya, Rafael, Luque-Ortega, Juan R, Fraser, Craig, Beetham, Henry, Schoenherr, Christina, Lopalco, Maria, Arends, Mark J, Frame, Margaret C, Qian, Bin-Zhi, Brunton, Valerie G, Carragher, Neil O, Unciti-Broceta, Asier

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Endothelial Jagged1 Antagonizes Dll4/Notch Signaling in Decidual Angiogenesis during Early Mouse Pregnancy von Marchetto, Nicole M, Begum, Salma, Wu, Tracy, O'Besso, Valerie, Yarborough, Christina C, Valero-Pacheco, Nuriban, Beaulieu, Aimee M, Kitajewski, Jan K, Shawber, Carrie J, Douglas, Nataki C

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A novel mode of inhibiting SRC improves drug efficacy and tolerability von Temps, Carolin, Lietha, Daniel, Webb, Emily R., Li, Xue-Feng, Dawson, John C., Muir, Morwenna, Macleod, Kenneth G., Valero, Teresa, Munro, Alison F., Contreras-Montoya, Rafael, Luque-Ortega, Juan R., Fraser, Craig, Beetham, Henry, Schoenherr, Christina, Lopalco, Maria, Arends, Mark J., Frame, Margaret C., Qian, Bin-Zhi, Brunton, Valerie G., Carragher, Neil O., Unciti-Broceta, Asier

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Abstract P2-11-04: Prognostic contribution of predicted sensitivity to endocrine therapy (SET) prior to neoadjuvant chemotherapy for stage II-III hormone receptor-positive and HER2... von Du, Lili, Yau, Christina, Brown-Swigart, Lamorna, Gould, Rebekah, Hirst, Gillian L, Consortium, I-SPY2, van der Noordaa, Marieke, Bedrosian, Isabelle, Layman, Rachel M, Valero, Vicente, van't Veer, Laura, Esserman, Laura, Symmans, W. Fraser

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Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma von Rivera, Edgardo, Meyers, Christina, Groves, Morris, Valero, Vicente, Francis, Deborah, Arun, Banu, Broglio, Kristine, Yin, Guosheng, Hortobagyi, Gabriel N., Buchholz, Thomas

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Patient Selection for Clinical Trials Eliminating Surgery for HER2-Positive Breast Cancer Treated with Neoadjuvant Systemic Therapy von Sun, Susie, van la Parra, Raquel F. D., Rauch, Gaiane M., Checka, Christina, Tadros, Audree B., Lucci, Anthony, Teshome, Mediget, Black, Dalliah, Hwang, Rosa F., Smith, Benjamin D., Krishnamurthy, Savitri, Valero, Vicente, Yang, Wei T., Kuerer, Henry M.

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CSF Viral Escape in Aviremic HIV-Infected Patients Receiving ART: Prevalence, Risk Factors and Neurocognitive Effects von Pérez-Valero, Ignacio, Ellis, Ronald, Heaton, Robert, Deutsch, Reena, Franklin, Donald, Clifford, David B., Collier, Ann, Gelman, Benjamin, Marra, Christina, McCutchan, J. Allen, Navis, Allison, Sacktor, Ned, Simpson, David, Grant, Igor, Letendre, Scott

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Abstract GS4-07: Assessing prognosis after neoadjuvant therapy: A comparison between anatomic ypAJCC staging, residual cancer burden class and neo-bioscore von van der Noordaa, Marieke EM, Yau, Christina, Shad, Sonal, Osdoit, Marie, Steenbruggen, Tessa G, de Croze, Diane, Hamy, Anne-Sophie, Lae, Marick, Reyal, Fabien, Del Monte-Millán, Maria, Martin, Miguel, Tarruella, Sara Lopez, Boughey, Judy C, Goetz, Matthew, Hoskin, Tanya, Gould, Rebecca, Valero, Vincent, Sonke, Gabe, van Seijen, Maartje, Wesseling, Jelle, Bartlett, John, Edge, Stephan, Kim, Mi-Ok, Abraham, Jean, Caldas, Carlos, Earl, Helena, Provenzano, Elena, Sammut, Stephen-John, Cameron, David, Graham, Ashley, Hall, Peter, MacKintosh, Lorna, Fan, Fang, Godwin, Andrew K, Schwensen, Kelsey, Sharma, Priyanka, DeMichele, Angela, Dunn, Janet, Hiller, Louise, Hayward, Larry, Thomas, Jeremy, Cole, Kimberley, Pusztai, Lajos, van 't Veer, Laura, Symmans, Fraser, Esserman, Laura

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