NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine von Valerie, Nicholas C K, Hagenkort, Anna, Page, Brent D G, Masuyer, Geoffrey, Rehling, Daniel, Carter, Megan, Bevc, Luka, Herr, Patrick, Homan, Evert, Sheppard, Nina G, Stenmark, Pål, Jemth, Ann-Sofie, Helleday, Thomas

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Pathways controlling dNTP pools to maintain genome stability von Rudd, Sean G., Valerie, Nicholas C.K., Helleday, Thomas

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Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies von Herold, Nikolas, Rudd, Sean G, Ljungblad, Linda, Sanjiv, Kumar, Myrberg, Ida Hed, Paulin, Cynthia B J, Heshmati, Yaser, Hagenkort, Anna, Kutzner, Juliane, Page, Brent D G, Calderón-Montaño, José M, Loseva, Olga, Jemth, Ann-Sofie, Bulli, Lorenzo, Axelsson, Hanna, Tesi, Bianca, Valerie, Nicholas C K, Höglund, Andreas, Bladh, Julia, Wiita, Elisée, Sundin, Mikael, Uhlin, Michael, Rassidakis, Georgios, Heyman, Mats, Tamm, Katja Pokrovskaja, Warpman-Berglund, Ulrika, Walfridsson, Julian, Lehmann, Sören, Grandér, Dan, Lundbäck, Thomas, Kogner, Per, Henter, Jan-Inge, Helleday, Thomas, Schaller, Torsten

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Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells von Page, Brent D. G., Valerie, Nicholas C. K., Wright, Roni H. G., Wallner, Olov, Isaksson, Rebecka, Carter, Megan, Rudd, Sean G., Loseva, Olga, Jemth, Ann-Sofie, Almlöf, Ingrid, Font-Mateu, Jofre, Llona-Minguez, Sabin, Baranczewski, Pawel, Jeppsson, Fredrik, Homan, Evert, Almqvist, Helena, Axelsson, Hanna, Regmi, Shruti, Gustavsson, Anna-Lena, Lundbäck, Thomas, Scobie, Martin, Strömberg, Kia, Stenmark, Pål, Beato, Miguel, Helleday, Thomas

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Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2 von Carter, Megan, Jemth, Ann-Sofie, Hagenkort, Anna, Page, Brent D. G., Gustafsson, Robert, Griese, Julia J., Gad, Helge, Valerie, Nicholas C. K., Desroses, Matthieu, Boström, Johan, Warpman Berglund, Ulrika, Helleday, Thomas, Stenmark, Pål

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Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM von Valerie, Nicholas C. K., Sanjiv, Kumar, Mortusewicz, Oliver, Zhang, Si Min, Alam, Seher, Pires, Maria J., Stigsdotter, Hannah, Rasti, Azita, Langelier, Marie-France, Rehling, Daniel, Throup, Adam, Purewal-Sidhu, Oryn, Desroses, Matthieu, Onireti, Jacob, Wakchaure, Prasad, Almlöf, Ingrid, Boström, Johan, Bevc, Luka, Benzi, Giorgia, Stenmark, Pål, Pascal, John M., Helleday, Thomas, Page, Brent D. G., Altun, Mikael

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NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir von Zhang, Si Min, Rehling, Daniel, Jemth, Ann-Sofie, Throup, Adam, Landázuri, Natalia, Almlöf, Ingrid, Göttmann, Mona, Valerie, Nicholas C.K., Borhade, Sanjay R., Wakchaure, Prasad, Page, Brent D.G., Desroses, Matthieu, Homan, Evert J., Scobie, Martin, Rudd, Sean G., Berglund, Ulrika Warpman, Söderberg-Nauclér, Cecilia, Stenmark, Pål, Helleday, Thomas

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Development of a chemical probe against NUDT15 von Zhang, Si Min, Desroses, Matthieu, Hagenkort, Anna, Valerie, Nicholas C. K., Rehling, Daniel, Carter, Megan, Wallner, Olov, Koolmeister, Tobias, Throup, Adam, Jemth, Ann-Sofie, Almlöf, Ingrid, Loseva, Olga, Lundbäck, Thomas, Axelsson, Hanna, Regmi, Shruti, Sarno, Antonio, Krämer, Andreas, Pudelko, Linda, Bräutigam, Lars, Rasti, Azita, Göttmann, Mona, Wiita, Elisée, Kutzner, Juliane, Schaller, Torsten, Kalderén, Christina, Cázares-Körner, Armando, Page, Brent D. G., Krimpenfort, Rosa, Eshtad, Saeed, Altun, Mikael, Rudd, Sean G., Knapp, Stefan, Scobie, Martin, Homan, Evert J., Berglund, Ulrika Warpman, Stenmark, Pål, Helleday, Thomas

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Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1 von Llona-Minguez, Sabin, Höglund, Andreas, Jacques, Sylvain A, Johansson, Lars, Calderón-Montaño, José Manuel, Claesson, Magnus, Loseva, Olga, Valerie, Nicholas C. K, Lundbäck, Thomas, Piedrafita, Javier, Maga, Giovanni, Crespan, Emmanuele, Meijer, Laurent, Burgos Morón, Estefanía, Baranczewski, Pawel, Hagbjörk, Ann-Louise, Svensson, Richard, Wiita, Elisee, Almlöf, Ingrid, Visnes, Torkild, Jeppsson, Fredrik, Sigmundsson, Kristmundur, Jensen, Annika Jenmalm, Artursson, Per, Jemth, Ann-Sofie, Stenmark, Pål, Warpman Berglund, Ulrika, Scobie, Martin, Helleday, Thomas

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Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors von Llona-Minguez, Sabin, Höglund, Andreas, Ghassemian, Artin, Desroses, Matthieu, Calderón-Montaño, José Manuel, Burgos Morón, Estefanía, Valerie, Nicholas C. K, Wiita, Elisee, Almlöf, Ingrid, Koolmeister, Tobias, Mateus, André, Cazares-Körner, Cindy, Sanjiv, Kumar, Homan, Evert, Loseva, Olga, Baranczewski, Pawel, Darabi, Masoud, Mehdizadeh, Amir, Fayezi, Shabnam, Jemth, Ann-Sofie, Warpman Berglund, Ulrika, Sigmundsson, Kristmundur, Lundbäck, Thomas, Jenmalm Jensen, Annika, Artursson, Per, Scobie, Martin, Helleday, Thomas

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Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells (vol 9, 250, 2018) von Page, BDG, Valerie, NCK, Wright, RHG, Wallner, O, Isaksson, R, Carter, M, Rudd, SG, Loseva, O, Jemth, A-S, Almlof, I

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Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells von Page, Brent D. G., Valerie, Nicholas C. K., Wright, Roni H. G., Wallner, Olov, Isaksson, Rebecka, Carter, Megan, Rudd, Sean G., Loseva, Olga, Jemth, Ann-Sofie, Almlöf, Ingrid, Font-Mateu, Jofre, Llona-Minguez, Sabin, Baranczewski, Pawel, Jeppsson, Fredrik, Homan, Evert, Almqvist, Helena, Axelsson, Hanna, Regmi, Shruti, Gustavsson, Anna-Lena, Lundbäck, Thomas, Scobie, Martin, Strömberg, Kia, Stenmark, Pål, Beato, Miguel, Helleday, Thomas

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Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors von Llona-Minguez, Sabin, Höglund, Andreas, Ghassemian, Artin, Desroses, Matthieu, Calderón-Montaño, José Manuel, Burgos Morón, Estefanía, Valerie, Nicholas C. K, Wiita, Elisee, Almlöf, Ingrid, Koolmeister, Tobias, Mateus, André, Cazares-Körner, Cindy, Sanjiv, Kumar, Homan, Evert, Loseva, Olga, Baranczewski, Pawel, Darabi, Masoud, Mehdizadeh, Amir, Fayezi, Shabnam, Jemth, Ann-Sofie, Warpman Berglund, Ulrika, Sigmundsson, Kristmundur, Lundbäck, Thomas, Jenmalm Jensen, Annika, Artursson, Per, Scobie, Martin, Helleday, Thomas

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Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors (vol 60, pg 4279, 2017) von Llona-Minguez, S, Hoglund, A, Ghassemian, A, Desroses, M, Calderon-Montano, JM, Moron, EB, Valerie, NCK, Wiita, E, Almlof, I, Koolmeister, T

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