Modeling of the human alveolar rhabdomyosarcoma Pax3-Foxo1 chromosome translocation in mouse myoblasts using CRISPR-Cas9 nuclease von Lagutina, Irina V, Valentine, Virginia, Picchione, Fabrizio, Harwood, Frank, Valentine, Marcus B, Villarejo-Balcells, Barbara, Carvajal, Jaime J, Grosveld, Gerard C

Volltext

Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma von DeNardo, Bradley D, Holloway, Michael P, Ji, Qinqin, Nguyen, Kevin T, Cheng, Yan, Valentine, Marcus B, Salomon, Arthur, Altura, Rachel A

Volltext

Stable Human FIX Expression After 0.9G Intrauterine Gene Transfer of Self-complementary Adeno-associated Viral Vector 5 and 8 in Macaques von Mattar, Citra NZ, Nathwani, Amit C, Waddington, Simon N, Dighe, Niraja, Kaeppel, Christine, Nowrouzi, Ali, Mcintosh, Jenny, Johana, Nuryanti B, Ogden, Bryan, Fisk, Nicholas M, Davidoff, Andrew M, David, Anna, Peebles, Donald, Valentine, Marcus B, Appelt, Jens-Uwe, von Kalle, Christof, Schmidt, Manfred, Biswas, Arijit, Choolani, Mahesh, Chan, Jerry KY

Volltext

Rapid Cell-Cycle Reentry and Cell Death after Acute Inactivation of the Retinoblastoma Gene Product in Postnatal Cochlear Hair Cells von Weber, Thomas, Corbett, Mary K., Chow, Lionel M. L., Valentine, Marcus B., Baker, Suzanne J., Zuo, Jian

Volltext

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity von Paulk, Nicole K., Pekrun, Katja, Zhu, Erhua, Nygaard, Sean, Li, Bin, Xu, Jianpeng, Chu, Kirk, Leborgne, Christian, Dane, Allison P., Haft, Annelise, Zhang, Yue, Zhang, Feijie, Morton, Chris, Valentine, Marcus B., Davidoff, Andrew M., Nathwani, Amit C., Mingozzi, Federico, Grompe, Markus, Alexander, Ian E., Lisowski, Leszek, Kay, Mark A.

Volltext

Loss of ChlR1 Helicase in Mouse Causes Lethality Due to the Accumulation of Aneuploid Cells Generated by Cohesion Defects and Placental Malformation von Inoue, Akira, Li, Tongyuan, Roby, Sarah K., Valentine, Marcus B., Inoue, Madoka, Boyd, Kelli, Kidd, Vincent J., Lahti, Jill M.

Volltext

Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue von Sharma, Richa, Sahoo, Sushree S., Honda, Masayoshi, Granger, Sophie L., Goodings, Charnise, Sanchez, Louis, Künstner, Axel, Busch, Hauke, Beier, Fabian, Pruett-Miller, Shondra M., Valentine, Marcus B., Fernandez, Alfonso G., Chang, Ti-Cheng, Géli, Vincent, Churikov, Dmitri, Hirschi, Sandrine, Pastor, Victor B., Boerries, Melanie, Lauten, Melchior, Kelaidi, Charikleia, Cooper, Megan A., Nicholas, Sarah, Rosenfeld, Jill A., Polychronopoulou, Sophia, Kannengiesser, Caroline, Saintomé, Carole, Niemeyer, Charlotte M., Revy, Patrick, Wold, Marc S., Spies, Maria, Erlacher, Miriam, Coulon, Stéphane, Wlodarski, Marcin W.

Volltext

Telomerase Expression Predicts Unfavorable Outcome in Osteosarcoma von SANDERS, Robert P, DRISSI, Rachid, BILLUPS, Catherine A, DAW, Najat C, VALENTINE, Marcus B, DOME, Jeffrey S

Volltext

Fusion of a Kinase Gene, ALK, to a Nucleolar Protein Gene, NPM, in Non-Hodgkin's Lymphoma von Morris, Stephan W., Kirstein, Mark N., Valentine, Marcus B., Dittmer, Kristopher G., Shapiro, David N., Saltman, David L., Look, A. Thomas

Volltext

Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis von TEITZ, Tal, INOUE, Madoka, RUBINSTEIN, Marcelo, HAKEM, Razqallah, WEISS, William A, LAHTI, Jill M, VALENTINE, Marcus B, KEJIN ZHU, REHG, Jerold E, WEI ZHAO, FINKELSTEIN, David, WANG, Yong-Dong, JOHNSON, Melissa D, CALABRESE, Christopher

Volltext

In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice von Yu, Yiling, Weber, Thomas, Yamashita, Tetsuji, Liu, Zhiyong, Valentine, Marcus B, Cox, Brandon C, Zuo, Jian

Volltext

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN von Kidd, Vincent J, Teitz, Tal, Wei, Tie, Valentine, Marcus B, Vanin, Elio F, Grenet, Jose, Valentine, Virginia A, Behm, Frederick G, Look, A. Thomas, Lahti, Jill M

Volltext

Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium von Liu, Zhiyong, Walters, Brandon J, Owen, Thomas, Brimble, Mark A, Steigelman, Katherine A, Zhang, LingLi, Mellado Lagarde, Marcia M, Valentine, Marcus B, Yu, Yiling, Cox, Brandon C, Zuo, Jian

Volltext

Inactivating Mutations in an SH2 Domain-Encoding Gene in X-Linked Lymphoproliferative Syndrome von Nichols, Kim E., Harkin, D. Paul, Levitz, Seth, Krainer, Michael, Kolquist, Kathryn Ann, Genovese, Cameo, Bernard, Amy, Ferguson, Martin, Zuo, Lin, Snyder, Eric, Buckler, Alan J., Wise, Carol, Ashley, Jennifer, Lovett, Michael, Valentine, Marcus B., Look, A. Thomas, Gerald, William, Housman, David E., Haber, Daniel A.

Volltext

Detection of MYCN Gene Amplification in Neuroblastoma by Fluorescence In Situ Hybridization: A Pediatric Oncology Group Study von Mathew, Prasad, Valentine, Marcus B., Bowman, Laura C., Rowe, Susan T., Nash, Michael B., Valentine, Virginia A., Cohn, Susan L., Castleberry, Robert P., Brodeur, Garrett M., Look, A. Thomas

Volltext

Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization von REARDON, D. A, MICHALKIEWICZ, E, KUN, L. E, SHAPIRO, D. N, LOOK, A. T, BOYETT, J. M, SUBLETT, J. E, ENTREKIN, R. E, RAGSDALE, S. T, VALENTINE, M. B, BEHM, F. G, LI, H, HEIDEMAN, R. L

Volltext

Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma von Chen, Xiang, Stewart, Elizabeth, Shelat, Anang A., Qu, Chunxu, Bahrami, Armita, Hatley, Mark, Wu, Gang, Bradley, Cori, McEvoy, Justina, Pappo, Alberto, Spunt, Sheri, Valentine, Marcus B., Valentine, Virginia, Krafcik, Fred, Lang, Walter H., Wierdl, Monika, Tsurkan, Lyudmila, Tolleman, Viktor, Federico, Sara M., Morton, Chris, Lu, Charles, Ding, Li, Easton, John, Rusch, Michael, Nagahawatte, Panduka, Wang, Jianmin, Parker, Matthew, Wei, Lei, Hedlund, Erin, Finkelstein, David, Edmonson, Michael, Shurtleff, Sheila, Boggs, Kristy, Mulder, Heather, Yergeau, Donald, Skapek, Steve, Hawkins, Douglas S., Ramirez, Nilsa, Potter, Philip M., Sandoval, John A., Davidoff, Andrew M., Mardis, Elaine R., Wilson, Richard K., Zhang, Jinghui, Downing, James R., Dyer, Michael A.

Volltext

Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia von Montefiori, Lindsey E., Bendig, Sonja, Gu, Zhaohui, Chen, Xiaolong, Polonen, Petri, Ma, Xiaotu, Murison, Alex, Zeng, Andy, Garcia-Prat, Laura, Dickerson, Kirsten, Iacobucci, Ilaria, Abdelhamed, Sherif, Hiltenbrand, Ryan, Mead, Paul E., Mehr, Cyrus M., Xu, Beisi, Cheng, Zhongshan, Chang, Ti-Cheng, Westover, Tamara, Ma, Jing, Stengel, Anna, Kimura, Shunsuke, Qu, Chunxu, Valentine, Marcus B., Rashkovan, Marissa, Luger, Selina, Litzow, Mark R., Rowe, Jacob M., den Boer, Monique L., Wang, Victoria, Yin, Jun, Kornblau, Steven M., Hunger, Stephen P., Loh, Mignon L., Pui, Ching-Hon, Yang, Wenjian, Crews, Kristine R., Roberts, Kathryn G., Yang, Jun J., Relling, Mary, Evans, William E., Stock, Wendy, Paietta, Elisabeth M., Ferrando, Adolfo A., Zhang, Jinghui, Kern, Wolfgang, Haferlach, Torsten, Wu, Gang, Dick, John E., Klco, Jeffery M., Haferlach, Claudia, Mullighan, Charles G.

Volltext

Inactivation of the NF1 Gene in Human Melanoma and Neuroblastoma Cell Lines Without Impaired Regulation of GTP·Ras von Johnson, Maureen R., Look, A. Thomas, DeClue, Jeffrey E., Valentine, Marcus B., Lowy, Douglas R.

Volltext

p27KIP1 Deletions in Childhood Acute Lymphoblastic Leukemia von Komuro, Hiroaki, Valentine, Marcus B., Rubnitz, Jeffrey E., Saito, Midori, Raimondi, Susana C., Carroll, Andrew J., Yi, Taolin, Sherr, Charles J., Look, A. Thomas

Volltext