Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells von Silva, Valdenizia R., Santos, Luciano de S., Dias, Rosane B., Quadros, Claudio A., Bezerra, Daniel P.

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Gouregine, an α -Gem-Dimethyltetradehydrocularine Alkaloid, and Other Aporphinoid Alkaloids from the Bark of Guatteria olivacea (Annonaceae) and Their In Vitro Cytotoxic Activities... von Costa, Emmanoel V, Freitas, José Guilherme C, Manickchand, Steve Pereira, Araújo, Morgana de S, Silva, Valdenizia R, Santos, Luciano de S, Koolen, Hector Henrique Ferreira, Silva, Felipe M A da, Soares, Milena Botelho Pereira, Bezerra, Daniel P

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Benzylated Dihydroflavones and Isoquinoline-Derived Alkaloids from the Bark of Diclinanona calycina (Annonaceae) and Their Cytotoxicities von Costa, Emmanoel V., Soares, Liviane do N., Chaar, Jamal da Silva, Silva, Valdenizia R., Santos, Luciano de S., Koolen, Hector H. F., Silva, Felipe M. A. da, Tavares, Josean F., Zengin, Gokhan, Soares, Milena B. P., Bezerra, Daniel P.

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Duguetia pycnastera Sandwith (Annonaceae) Leaf Essential Oil Inhibits HepG2 Cell Growth In Vitro and In Vivo von Costa, Emmanoel V, de Souza, César A S, Galvão, Alexandre F C, Silva, Valdenizia R, Santos, Luciano de S, Dias, Rosane B, Rocha, Clarissa A Gurgel, Soares, Milena B P, da Silva, Felipe M A, Koolen, Hector H F, Bezerra, Daniel P

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Antitumor Effect of Guatteria olivacea R. E. Fr. (Annonaceae) Leaf Essential Oil in Liver Cancer von Galvão, Alexandre F. C., Araújo, Morgana de S., Silva, Valdenizia R., Santos, Luciano de S., Dias, Rosane B., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Silva, Felipe M. A. da, Koolen, Hector H. F., Zengin, Gokhan, Costa, Emmanoel V., Bezerra, Daniel P.

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New ruthenium-xanthoxylin complex eliminates colorectal cancer stem cells by targeting the heat shock protein 90 chaperone von Santos, Luciano de S., Silva, Valdenizia R., de Castro, Maria V. L., Dias, Rosane B., Valverde, Ludmila de F., Rocha, Clarissa A. G., Soares, Milena B. P., Quadros, Claudio A., dos Santos, Edjane R., Oliveira, Regina M. M., Carlos, Rose M., Nogueira, Paulo C. L., Bezerra, Daniel P.

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Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine–Thiosemicarbazone Derivatives von Sousa, Gleyton, de Almeida, Maria C. F, Lócio, Lucas L, dos Santos, Vanda L, Bezerra, Daniel P, Silva, Valdenizia R, de Almeida, Sinara M. V, Simon, Alice, Honório, Thiago da S, Cabral, Lucio M, Castro, Rosane N, de Moura, Ricardo O, Kümmerle, Arthur E

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A novel ruthenium complex with 5-fluorouracil suppresses colorectal cancer stem cells by inhibiting Akt/mTOR signaling von Silva, Valdenizia R., Santos, Luciano de S., de Castro, Maria V. L., Dias, Rosane B., Valverde, Ludmila de F., Rocha, Clarissa A. G., Soares, Milena B. P., Quadros, Claudio A., Correa, Rodrigo S., Batista, Alzir A., Bezerra, Daniel P.

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Semi-synthesis of β-keto-1,2,3-triazole derivatives from ethinylestradiol and evaluation of the cytotoxic activity von Queiroz, Thayane M., Orozco, Erika V.M., Silva, Valdenizia R., Santos, Luciano S., Soares, Milena B.P., Bezerra, Daniel P., Porto, André L.M.

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Challenges and Therapeutic Opportunities of Autophagy in Cancer Therapy von Silva, Valdenizia R., Neves, Sara P., Santos, Luciano de S., Dias, Rosane B., Bezerra, Daniel P.

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Exploring the BSA- and DNA-binding, cytotoxicity, and cell cycle evaluation of ternary copper(II)/diimine complexes with N , N -dibenzyl- N '-benzoylthiourea as promising metallodr... von Gonçalves, Guilherme R, Teixeira, Tamara, Bezerra, Daniel P, Soares, Milena B P, Silva, Valdenizia R, Santos, Luciano de S, Batista, Alzir A, Oliveira, Katia M, Correa, Rodrigo S

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Pleonotoquinones, Cytotoxic Oxepinenaphthoquinones from Pleonotoma jasminifolia von Anselmo, Leandro T., de Souza, Thalisson A., Brito, Thiago A. M., Peres, Eldrinei G., da Silva, Felipe M. A., Silva, Valdenizia R., Santos, Luciano de S., Soares, Milena B. P., Bezerra, Daniel P., Costa, Emmanoel V., Sipoloni, Victor M., de Medeiros, Lívia S., da Silva, Marcelo S., Tavares, Josean F., Gomes, Waldireny R., Koolen, Hector H. F.

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Antitumor Effect of the Essential Oil from the Leaves of Croton matourensis Aubl. (Euphorbiaceae) von Lima, Emilly J S P de, Alves, Rafaela G, D Elia, Gigliola M A, Anunciação, Talita A da, Silva, Valdenizia R, Santos, Luciano de S, Soares, Milena B P, Cardozo, Nállarett M D, Costa, Emmanoel V, Silva, Felipe M A da, Koolen, Hector H F, Bezerra, Daniel P

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In vitro and in vivo inhibition of HCT116 cells by essential oils from bark and leaves of Virola surinamensis (Rol. ex Rottb.) Warb. (Myristicaceae) von Anunciação, Talita A. da, Costa, Rafaela G.A., Lima, Emilly J.S.P. de, Silva, Valdenizia R., Santos, Luciano de S., Soares, Milena B.P., Dias, Rosane B., Rocha, Clarissa A. Gurgel, Costa, Emmanoel V., Silva, Felipe M.A. da, Koolen, Hector H.F., Bezerra, Daniel P.

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Structure-Based Molecular Networking for the Target Discovery of Oxahomoaporphine and 8‑Oxohomoaporphine Alkaloids from Duguetia surinamensis von Paz, Weider H. P, de Oliveira, Rodolfo N, Heerdt, Gabriel, Angolini, Célio F. F, S. de Medeiros, Lívia, Silva, Valdenizia R, Santos, Luciano S, Soares, Milena B. P, Bezerra, Daniel P, Morgon, Nelson H, Almeida, Jackson R. G. S, da Silva, Felipe M. A, Costa, Emmanoel V, Koolen, Hector H. F

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Essential oil from leaves of Conobea scoparioides (Cham. & Schltdl.) Benth. (Plantaginaceae) causes cell death in HepG2 cells and inhibits tumor development in a xenograft model von Lima, Emilly J.S.P. de, Fontes, Sheila S., Nogueira, Mateus L., Silva, Valdenizia R., Santos, Luciano de S., D’Elia, Gigliola M.A., Dias, Rosane B., Sales, Caroline B.S., Rocha, Clarissa A. Gurgel, Vannier-Santos, Marcos A., Soares, Milena B.P., Costa, Emmanoel V., Silva, Felipe M.A. da, Koolen, Hector H.F., Bezerra, Daniel P.

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Cyperus articulatus L. (Cyperaceae) Rhizome Essential Oil Causes Cell Cycle Arrest in the G2/M Phase and Cell Death in HepG2 Cells and Inhibits the Development of Tumors in a Xenog... von Nogueira, Mateus L., Lima, Emilly J. S. P. de, Adrião, Asenate A. X., Fontes, Sheila S., Silva, Valdenizia R., Santos, Luciano de S., Soares, Milena B. P., Dias, Rosane B., Rocha, Clarissa A. Gurgel, Costa, Emmanoel V., Silva, Felipe M. A. da, Vannier-Santos, Marcos A., Cardozo, Nállarett M. D., Koolen, Hector H. F., Bezerra, Daniel P.

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Fast synthesis of amides from ethyl salicylate under microwave radiation in a solvent-free system von Lima, Rafaely N, Silva, Valdenizia R, Santos, Luciano de S, Bezerra, Daniel P, Soares, Milena B. P, Porto, André L. M

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Piper anisum as a promising new source of bioactive metabolites von Batista, Danilo, Campos, Patrícia, Silva, Valdenizia R., de S. Santos, Luciano, Bezerra, Daniel P., Soares, Milena B. P., Colepicolo, Pio, Zambotti-Villela, Leonardo, Pinto, Ernani, Araújo, Floricea M., Martins, Dirceu, Fernandez, Luzimar G., Ligterink, Wilco, Canuto, Gisele A. B., de Cerqueira, Martins Dias, Ribeiro, Paulo R.

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Bioactive compounds from Vellozia pyrantha A.A.Conc: A metabolomics and multivariate statistical analysis approach von Ribeiro, Luiz A.F., dos Santos, Iago B.F., Ferraz, Caline G., de Souza-Neta, Lourdes C., Silva, Valdenizia R., Santos, Luciano de S., Bezerra, Daniel P., Soares, Milena B.P., Zambotti-Villela, Leonardo, Colepicolo, Pio, Ferreira, Antonio G., Araújo, Floricéa M., Ribeiro, Paulo R.

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