Post-transcriptional regulation on a global scale: form and function of Csr/Rsm systems von Romeo, Tony, Vakulskas, Christopher A., Babitzke, Paul

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Evaluation and Reduction of CRISPR Off-Target Cleavage Events von Vakulskas, Christopher A., Behlke, Mark A.

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Global role of the bacterial post-transcriptional regulator CsrA revealed by integrated transcriptomics von Potts, Anastasia H., Vakulskas, Christopher A., Pannuri, Archana, Yakhnin, Helen, Babitzke, Paul, Romeo, Tony

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Identification of preexisting adaptive immunity to Cas9 proteins in humans von Charlesworth, Carsten T., Deshpande, Priyanka S., Dever, Daniel P., Camarena, Joab, Lemgart, Viktor T., Cromer, M. Kyle, Vakulskas, Christopher A., Collingwood, Michael A., Zhang, Liyang, Bode, Nicole M., Behlke, Mark A., Dejene, Beruh, Cieniewicz, Brandon, Romano, Rosa, Lesch, Benjamin J., Gomez-Ospina, Natalia, Mantri, Sruthi, Pavel-Dinu, Mara, Weinberg, Kenneth I., Porteus, Matthew H.

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A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells von Vakulskas, Christopher A., Dever, Daniel P., Rettig, Garrett R., Turk, Rolf, Jacobi, Ashley M., Collingwood, Michael A., Bode, Nicole M., McNeill, Matthew S., Yan, Shuqi, Camarena, Joab, Lee, Ciaran M., Park, So Hyun, Wiebking, Volker, Bak, Rasmus O., Gomez-Ospina, Natalia, Pavel-Dinu, Mara, Sun, Wenchao, Bao, Gang, Porteus, Matthew H., Behlke, Mark A.

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Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants von Zhang, Liyang, Li, Gen, Zhang, Yingxiao, Cheng, Yanhao, Roberts, Nathaniel, Glenn, Steve E, DeZwaan-McCabe, Diane, Rube, H Tomas, Manthey, Jeff, Coleman, Gary, Vakulskas, Christopher A, Qi, Yiping

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Regulation of bacterial virulence by Csr (Rsm) systems von Vakulskas, Christopher A, Potts, Anastasia H, Babitzke, Paul, Ahmer, Brian M M, Romeo, Tony

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Genomic Targets and Features of BarA-UvrY (-SirA) Signal Transduction Systems von Zere, Tesfalem R, Vakulskas, Christopher A, Leng, Yuanyuan, Pannuri, Archana, Potts, Anastasia H, Dias, Raquel, Tang, Dongjie, Kolaczkowski, Bryan, Georgellis, Dimitris, Ahmer, Brian M M, Romeo, Tony

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Generation of the transgene-free canker-resistant Citrus sinensis using Cas12a/crRNA ribonucleoprotein in the T0 generation von Su, Hang, Wang, Yuanchun, Xu, Jin, Omar, Ahmad A., Grosser, Jude W., Calovic, Milica, Zhang, Liyang, Feng, Yu, Vakulskas, Christopher A., Wang, Nian

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Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases von Yarnall, Matthew T. N., Ioannidi, Eleonora I., Schmitt-Ulms, Cian, Krajeski, Rohan N., Lim, Justin, Villiger, Lukas, Zhou, Wenyuan, Jiang, Kaiyi, Garushyants, Sofya K., Roberts, Nathaniel, Zhang, Liyang, Vakulskas, Christopher A., Walker, John A., Kadina, Anastasia P., Zepeda, Adrianna E., Holden, Kevin, Ma, Hong, Xie, Jun, Gao, Guangping, Foquet, Lander, Bial, Greg, Donnelly, Sara K., Miyata, Yoshinari, Radiloff, Daniel R., Henderson, Jordana M., Ujita, Andrew, Abudayyeh, Omar O., Gootenberg, Jonathan S.

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Comparison of CRISPR-Cas9/Cas12a Ribonucleoprotein Complexes for Genome Editing Efficiency in the Rice Phytoene Desaturase (OsPDS) Gene von Banakar, Raviraj, Schubert, Mollie, Collingwood, Michael, Vakulskas, Christopher, Eggenberger, Alan L., Wang, Kan

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Antagonistic control of the turnover pathway for the global regulatory sRNA CsrB by the CsrA and CsrD proteins von Vakulskas, Christopher A, Leng, Yuanyuan, Abe, Hazuki, Amaki, Takumi, Okayama, Akihiro, Babitzke, Paul, Suzuki, Kazushi, Romeo, Tony

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CsrA activates flhDC expression by protecting flhDC mRNA from RNase E‐mediated cleavage von Yakhnin, Alexander V., Baker, Carol S., Vakulskas, Christopher A., Yakhnin, Helen, Berezin, Igor, Romeo, Tony, Babitzke, Paul

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Amount of Cas9 protein introduced into mouse embryos via electroporation affects the genome-editing rate von WAKE, Yui, VAKULSKAS, Christopher A., GLENN, Steve E., KANEKO, Takehito

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Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells von Baik, Ron, Cromer, M. Kyle, Glenn, Steve E., Vakulskas, Christopher A., Chmielewski, Kay O., Dudek, Amanda M., Feist, William N., Klermund, Julia, Shipp, Suzette, Cathomen, Toni, Dever, Daniel P., Porteus, Matthew H.

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Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes von Zhang, Liyang, Rube, H Tomas, Vakulskas, Christopher A, Behlke, Mark A, Bussemaker, Harmen J, Pufall, Miles A

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AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines von Zhang, Liyang, Zuris, John A., Viswanathan, Ramya, Edelstein, Jasmine N., Turk, Rolf, Thommandru, Bernice, Rube, H. Tomas, Glenn, Steve E., Collingwood, Michael A., Bode, Nicole M., Beaudoin, Sarah F., Lele, Swarali, Scott, Sean N., Wasko, Kevin M., Sexton, Steven, Borges, Christopher M., Schubert, Mollie S., Kurgan, Gavin L., McNeill, Matthew S., Fernandez, Cecilia A., Myer, Vic E., Morgan, Richard A., Behlke, Mark A., Vakulskas, Christopher A.

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Circuitry Linking the Catabolite Repression and Csr Global Regulatory Systems of Escherichia coli von Pannuri, Archana, Vakulskas, Christopher A, Zere, Tesfalem, McGibbon, Louise C, Edwards, Adrianne N, Georgellis, Dimitris, Babitzke, Paul, Romeo, Tony

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Dual Posttranscriptional Regulation via a Cofactor-Responsive mRNA Leader von Patterson-Fortin, Laura M., Vakulskas, Christopher A., Yakhnin, Helen, Babitzke, Paul, Romeo, Tony

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Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells von Cromer, M. Kyle, Camarena, Joab, Martin, Renata M., Lesch, Benjamin J., Vakulskas, Christopher A., Bode, Nicole M., Kurgan, Gavin, Collingwood, Michael A., Rettig, Garrett R., Behlke, Mark A., Lemgart, Viktor T., Zhang, Yankai, Goyal, Ankush, Zhao, Feifei, Ponce, Ezequiel, Srifa, Waracharee, Bak, Rasmus O., Uchida, Naoya, Majeti, Ravindra, Sheehan, Vivien A., Tisdale, John F., Dever, Daniel P., Porteus, Matthew H.

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