The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia von Shi, J, Wang, E, Zuber, J, Rappaport, A, Taylor, M, Johns, C, Lowe, S W, Vakoc, C R

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WRAD: enabler of the SET1-family of H3K4 methyltransferases von Ernst, Patricia, Vakoc, Christopher R

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Proximity among Distant Regulatory Elements at the β-Globin Locus Requires GATA-1 and FOG-1 von Vakoc, Christopher R., Letting, Danielle L., Gheldof, Nele, Sawado, Tomoyuki, Bender, M.A., Groudine, Mark, Weiss, Mitchell J., Dekker, Job, Blobel, Gerd A.

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The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;NrasG12D acute myeloid leukemia von Shi, J, Wang, E, Zuber, J, Rappaport, A, Taylor, M, Johns, C, Lowe, S W, Vakoc, C R

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653 Endogenous DOPA inhibits melanoma through suppression of CHRM1 signaling von Doepner, M., Natale, C., Lee, I., Brathwaite, R., Venkat, S., Kim, S., Wei, Y., Vakoc, C., Katzenellenbogen, J., Katzenellenbogen, B., Feigin, M., Ridky, T.W.

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Histone H3 Lysine 9 Methylation and HP1γ Are Associated with Transcription Elongation through Mammalian Chromatin von Vakoc, Christopher R., Mandat, Sean A., Olenchock, Benjamin A., Blobel, Gerd A.

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FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1 von Hong, Wei, Nakazawa, Minako, Chen, Ying-Yu, Kori, Rajashree, Vakoc, Christopher R, Rakowski, Carrie, Blobel, Gerd A

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Global regulation of erythroid gene expression by transcription factor GATA-1 von Welch, John J., Watts, Jason A., Vakoc, Christopher R., Yao, Yu, Wang, Hao, Hardison, Ross C., Blobel, Gerd A., Chodosh, Lewis A., Weiss, Mitchell J.

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The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9; Nras super(G12D) acute myeloid leukemia von Shi, J, Wang, E, Zuber, J, Rappaport, A, Taylor, M, Johns, C, Lowe, S W, Vakoc, C R

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Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma von Snuderl, Matija, Batista, Ana, Kirkpatrick, Nathaniel D., Ruiz de Almodovar, Carmen, Riedemann, Lars, Walsh, Elisa C., Anolik, Rachel, Huang, Yuhui, Martin, John D., Kamoun, Walid, Knevels, Ellen, Schmidt, Thomas, Farrar, Christian T., Vakoc, Benjamin J., Mohan, Nishant, Chung, Euiheon, Roberge, Sylvie, Peterson, Teresa, Bais, Carlos, Zhelyazkova, Boryana H., Yip, Stephen, Hasselblatt, Martin, Rossig, Claudia, Niemeyer, Elisabeth, Ferrara, Napoleone, Klagsbrun, Michael, Duda, Dan G., Fukumura, Dai, Xu, Lei, Carmeliet, Peter, Jain, Rakesh K.

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Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis von Roe, Jae-Seok, Hwang, Chang-Il, Somerville, Tim D.D., Milazzo, Joseph P., Lee, Eun Jung, Da Silva, Brandon, Maiorino, Laura, Tiriac, Hervé, Young, C. Megan, Miyabayashi, Koji, Filippini, Dea, Creighton, Brianna, Burkhart, Richard A., Buscaglia, Jonathan M., Kim, Edward J., Grem, Jean L., Lazenby, Audrey J., Grunkemeyer, James A., Hollingsworth, Michael A., Grandgenett, Paul M., Egeblad, Mikala, Park, Youngkyu, Tuveson, David A., Vakoc, Christopher R.

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A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response von Alpatov, Roman, Lesch, Bluma J., Nakamoto-Kinoshita, Mika, Blanco, Andres, Chen, Shuzhen, Stützer, Alexandra, Armache, Karim J., Simon, Matthew D., Xu, Chao, Ali, Muzaffar, Murn, Jernej, Prisic, Sladjana, Kutateladze, Tatiana G., Vakoc, Christopher R., Min, Jinrong, Kingston, Robert E., Fischle, Wolfgang, Warren, Stephen T., Page, David C., Shi, Yang

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SOAT1 promotes mevalonate pathway dependency in pancreatic cancer von Oni, Tobiloba E, Biffi, Giulia, Baker, Lindsey A, Hao, Yuan, Tonelli, Claudia, Somerville, Tim D D, Deschênes, Astrid, Belleau, Pascal, Hwang, Chang-Il, Sánchez-Rivera, Francisco J, Cox, Hilary, Brosnan, Erin, Doshi, Abhishek, Lumia, Rebecca P, Khaledi, Kimia, Park, Youngkyu, Trotman, Lloyd C, Lowe, Scott W, Krasnitz, Alexander, Vakoc, Christopher R, Tuveson, David A

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia von Zuber, Johannes, Shi, Junwei, Wang, Eric, Rappaport, Amy R., Herrmann, Harald, Sison, Edward A., Magoon, Daniel, Qi, Jun, Blatt, Katharina, Wunderlich, Mark, Taylor, Meredith J., Johns, Christopher, Chicas, Agustin, Mulloy, James C., Kogan, Scott C., Brown, Patrick, Valent, Peter, Bradner, James E., Lowe, Scott W., Vakoc, Christopher R.

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An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance von Zuber, Johannes, Rappaport, Amy R, Luo, Weijun, Wang, Eric, Chen, Chong, Vaseva, Angelina V, Shi, Junwei, Weissmueller, Susann, Fellmann, Christof, Fellman, Christof, Taylor, Meredith J, Weissenboeck, Martina, Graeber, Thomas G, Kogan, Scott C, Vakoc, Christopher R, Lowe, Scott W

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BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc von Delmore, Jake E., Issa, Ghayas C., Lemieux, Madeleine E., Rahl, Peter B., Shi, Junwei, Jacobs, Hannah M., Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M., Qi, Jun, Chesi, Marta, Schinzel, Anna C., McKeown, Michael R., Heffernan, Timothy P., Vakoc, Christopher R., Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G., Young, Richard A., Hahn, William C., Anderson, Kenneth C., Kung, Andrew L., Bradner, James E., Mitsiades, Constantine S.

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MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity von Skucha, Anna, Ebner, Jessica, Schmöllerl, Johannes, Roth, Mareike, Eder, Thomas, César-Razquin, Adrián, Stukalov, Alexey, Vittori, Sarah, Muhar, Matthias, Lu, Bin, Aichinger, Martin, Jude, Julian, Müller, André C., Győrffy, Balázs, Vakoc, Christopher R., Valent, Peter, Bennett, Keiryn L., Zuber, Johannes, Superti-Furga, Giulio, Grebien, Florian

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A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence von Lu, Bin, Klingbeil, Olaf, Tarumoto, Yusuke, Somerville, Tim D.D., Huang, Yu-Han, Wei, Yiliang, Wai, Dorothy C., Low, Jason K.K., Milazzo, Joseph P., Wu, Xiaoli S., Cao, Zhendong, Yan, Xiaomei, Demerdash, Osama E., Huang, Gang, Mackay, Joel P., Kinney, Justin B., Shi, Junwei, Vakoc, Christopher R.

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Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity von Aho, Erin R., Wang, Jing, Gogliotti, Rocco D., Howard, Gregory C., Phan, Jason, Acharya, Pankaj, Macdonald, Jonathan D., Cheng, Ken, Lorey, Shelly L., Lu, Bin, Wenzel, Sabine, Foshage, Audra M., Alvarado, Joseph, Wang, Feng, Shaw, J. Grace, Zhao, Bin, Weissmiller, April M., Thomas, Lance R., Vakoc, Christopher R., Hall, Matthew D., Hiebert, Scott W., Liu, Qi, Stauffer, Shaun R., Fesik, Stephen W., Tansey, William P.

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SCL and associated proteins distinguish active from repressive GATA transcription factor complexes von Tripic, Tamara, Deng, Wulan, Cheng, Yong, Zhang, Ying, Vakoc, Christopher R., Gregory, Gregory D., Hardison, Ross C., Blobel, Gerd A.

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