CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency von Matharu, Navneet, Rattanasopha, Sawitree, Tamura, Serena, Maliskova, Lenka, Wang, Yi, Bernard, Adelaide, Hardin, Aaron, Eckalbar, Walter L, Vaisse, Christian, Ahituv, Nadav

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A statistical approach for array CGH data analysis von Picard, Franck, Robin, Stephane, Lavielle, Marc, Vaisse, Christian, Daudin, Jean-Jacques

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Leptin regulation of bone resorption by the sympathetic nervous system and CART von Takeda, Shu, Liu, Xiuyun, Elefteriou, Florent, Bannon, Tony W, Clement, Karine, Yang, Xiangli, Richards, William G, Kondo, Hisataka, Karsenty, Gerard, Vaisse, Christian, Ahn, Jong Deok, Starbuck, Michael, Noda, Masaki

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Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity von Vaisse, C, Clement, K, Durand, E, Hercberg, S, Guy-Grand, B, Froguel, P

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Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier von Yulyaningsih, Ernie, Rudenko, Ivan A., Valdearcos, Martin, Dahlén, Emma, Vagena, Eirini, Chan, Alvin, Alvarez-Buylla, Arturo, Vaisse, Christian, Koliwad, Suneil K., Xu, Allison W.

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Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans von Srinivasan, Supriya, Lubrano-Berthelier, Cecile, Govaerts, Cedric, Picard, Franck, Santiago, Pamela, Conklin, Bruce R, Vaisse, Christian

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Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR von Ersoy, Baran A, Pardo, Leonardo, Zhang, Sumei, Thompson, Darren A, Millhauser, Glenn, Govaerts, Cedric, Vaisse, Christian

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The Association of Serum Leptin with Mortality in Older Adults von Mishra, Suruchi, Harris, Tamara B, Hsueh, Wen-Chi, Hue, Trisha, Leak, Tennille S, Li, Rongling, Mehta, Mira, Vaisse, Christian, Sahyoun, Nadine R

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Identification of AgRP cells in the murine hindbrain that drive feeding von Bachor, Tomas P., Hwang, Eunsang, Yulyaningsih, Ernie, Attal, Kush, Mifsud, Francois, Pham, Viana, Vagena, Eirini, Huarcaya, Renzo, Valdearcos, Martin, Vaisse, Christian, Williams, Kevin W., Emmerson, Paul J., Xu, Allison W.

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Postnatal Dynamic Ciliary ARL13B and ADCY3 Localization in the Mouse Brain von Brewer, Katlyn K, Brewer, Kathryn M, Terry, Tiffany T, Caspary, Tamara, Vaisse, Christian, Berbari, Nicolas F

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MRAP2 regulates energy homeostasis by promoting primary cilia localization of MC4R von Bernard, Adelaide, Ojeda Naharros, Irene, Yue, Xinyu, Mifsud, Francois, Blake, Abbey, Bourgain-Guglielmetti, Florence, Ciprin, Jordi, Zhang, Sumei, McDaid, Erin, Kim, Kellan, Nachury, Maxence V, Reiter, Jeremy F, Vaisse, Christian

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction von Froguel, Philippe, Clément, Karine, Vaisse, Christian, Lahlou, Najiba, Cabrol, Sylvie, Pelloux, Veronique, Cassuto, Dominique, Gourmelen, Micheline, Dina, Christian, Chambaz, Jean, Lacorte, Jean-Marc, Basdevant, Arnaud, Bougnères, Pierre, Lebouc, Yves, Guy-Grand, Bernard

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Unexpected Endocrine Features and Normal Pigmentation in a Young Adult Patient Carrying a Novel Homozygous Mutation in the POMC Gene von Clément, Karine, Dubern, Béatrice, Mencarelli, Monica, Czernichow, Paul, Ito, Shosuke, Wakamatsu, Kazumasa, Barsh, Gregory S., Vaisse, Christian, Leger, Juliane

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Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions von Evans, Daniel S, Calton, Melissa A, Kim, Mee J, Kwok, Pui-Yan, Miljkovic, Iva, Harris, Tamara, Koster, Annemarie, Liu, Yongmei, Tranah, Gregory J, Ahituv, Nadav, Hsueh, Wen-Chi, Vaisse, Christian

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Cilia and Obesity von Vaisse, Christian, Reiter, Jeremy F, Berbari, Nicolas F

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Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight von Wang, Yi, Bernard, Adelaide, Comblain, Fanny, Yue, Xinyu, Paillart, Christophe, Zhang, Sumei, Reiter, Jeremy F., Vaisse, Christian

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Molecular Genetics of Human Obesity-Associated MC4R Mutations von LUBRANO-BERTHELIER, CECILE, CAVAZOS, MARTHA, DUBERN, BEATRICE, SHAPIRO, ASTRID, LE STUNFF, CATHERINE, ZHANG, SUMEI, PICART, FRANCK, GOVAERTS, CEDRIC, FROGUEL, PHILIPPE, BOUGNÈRES, PIERRE, CLEMENT, KARINE, VAISSE, CHRISTIAN

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Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity von Siljee, Jacqueline E., Wang, Yi, Bernard, Adelaide A., Ersoy, Baran A., Zhang, Sumei, Marley, Aaron, Von Zastrow, Mark, Reiter, Jeremy F., Vaisse, Christian

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High Prevalence of Glucose-6-Phosphate Dehydrogenase Deficiency without Gene Mutation Suggests a Novel Genetic Mechanism Predisposing to Ketosis-Prone Diabetes von Sobngwi, Eugene, Gautier, Jean-François, Kevorkian, Jean-Philippe, Villette, Jean-Marie, Riveline, Jean-Pierre, Zhang, Sumei, Vexiau, Patrick, Leal, Suzanne M., Vaisse, Christian, Mauvais-Jarvis, Franck

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Detailed 3-dimensional body shape features predict body composition, blood metabolites, and functional strength: the Shape Up! studies von Ng, Bennett K, Sommer, Markus J, Wong, Michael C, Pagano, Ian, Nie, Yilin, Fan, Bo, Kennedy, Samantha, Bourgeois, Brianna, Kelly, Nisa, Liu, Yong E, Hwaung, Phoenix, Garber, Andrea K, Chow, Dominic, Vaisse, Christian, Curless, Brian, Heymsfield, Steven B, Shepherd, John A

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