Mitochondrial dysfunction remodels one-carbon metabolism in human cells von Bao, Xiaoyan Robert, Ong, Shao-En, Goldberger, Olga, Peng, Jun, Sharma, Rohit, Thompson, Dawn A, Vafai, Scott B, Cox, Andrew G, Marutani, Eizo, Ichinose, Fumito, Goessling, Wolfram, Regev, Aviv, Carr, Steven A, Clish, Clary B, Mootha, Vamsi K

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A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering von To, Tsz-Leung, Cuadros, Alejandro M., Shah, Hardik, Hung, Wendy H.W., Li, Yang, Kim, Sharon H., Rubin, Daniel H.F., Boe, Ryan H., Rath, Sneha, Eaton, John K., Piccioni, Federica, Goodale, Amy, Kalani, Zohra, Doench, John G., Root, David E., Schreiber, Stuart L., Vafai, Scott B., Mootha, Vamsi K.

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Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors von Vafai, Scott B, Mevers, Emily, Higgins, Kathleen W, Fomina, Yevgenia, Zhang, Jianming, Mandinova, Anna, Newman, David, Shaw, Stanley Y, Clardy, Jon, Mootha, Vamsi K

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Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans von Lennerz, Belinda S., Vafai, Scott B., Delaney, Nigel F., Clish, Clary B., Deik, Amy A., Pierce, Kerry A., Ludwig, David S., Mootha, Vamsi K.

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Mitochondrial disorders as windows into an ancient organelle von Vafai, Scott B., Mootha, Vamsi K.

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Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting PCSK9 in Nonhuman Primate and Mouse Models von Lee, Richard G., Mazzola, Anne Marie, Braun, Maurine C., Platt, Colin, Vafai, Scott B., Kathiresan, Sekar, Rohde, Ellen, Bellinger, Andrew M., Khera, Amit V.

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Protein phosphatase 2A methylation: a link between elevated plasma homocysteine and Alzheimer’s Disease von Vafai, Scott B, Stock, Jeffry B

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Regression of Drug-Resistant Lung Cancer by the Combination of Rosiglitazone and Carboplatin von GIRNUN, Geoffrey D, LIANG CHEN, NASERI, Elnaz, BUCKLEY, Stephanie, DANAN LI, FORCE, Jeremy, MCNAMARA, Kate, DEMETRI, George, SPIEGELMAN, Bruce M, WONG, Kwok-Kin, SILVAGGI, Jessica, DRAPKIN, Ronny, CHIRIEAC, Lucian R, PADERA, Robert F, UPADHYAY, Rabi, VAFAI, Scott B, WEISSLEDER, Ralph, MAHMOOD, Umar

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A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology von Pagliarini, David J., Calvo, Sarah E., Chang, Betty, Sheth, Sunil A., Vafai, Scott B., Ong, Shao-En, Walford, Geoffrey A., Sugiana, Canny, Boneh, Avihu, Chen, William K., Hill, David E., Vidal, Marc, Evans, James G., Thorburn, David R., Carr, Steven A., Mootha, Vamsi K.

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PGC1α Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis von BHALLA, Kavita, HWANG, Bor Jang, GIRNUN, Geoffrey D, DEWI, Ruby E, OU, Lihui, TWADDEL, William, FANG, Hong-Bin, VAFAI, Scott B, VAZQUEZ, Francesca, PUIGSERVER, Pere, BOROS, Laszlo

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Atypical case of Wolfram syndrome revealed through targeted exome sequencing in a patient with suspected mitochondrial disease von Lieber, Daniel S, Vafai, Scott B, Horton, Laura C, Slate, Nancy G, Liu, Shangtao, Borowsky, Mark L, Calvo, Sarah E, Schmahmann, Jeremy D, Mootha, Vamsi K

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Sympathetic Denervation of the Common Hepatic Artery Lessens Glucose Intolerance in the Fat- and Fructose-Fed Dog von Kraft, Guillaume, Vrba, Anthony, Scott, Melanie, Allen, Eric, Edgerton, Dale S, Williams, Phil E, Vafai, Scott B, Azamian, Bobak R, Cherrington, Alan D

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A Common Pathway for a Rare Disease? von Vafai, Scott B., Mootha, Vamsi K.

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Synergy between PPARγ Ligands and Platinum-Based Drugs in Cancer von Girnun, Geoffrey D., Naseri, Elnaz, Vafai, Scott B., Qu, Lishu, Szwaya, Jeffrey D., Bronson, Roderick, Alberta, John A., Spiegelman, Bruce M.

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Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors von Vafai, Scott B, Mevers, Emily, Higgins, Kathleen W, Fomina, Yevgenia, Zhang, Jianming, Mandinova, Anna, Newman, David, Shaw, Stanley Y, Clardy, Jon, Mootha, Vamsi K

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Medicine. A common pathway for a rare disease? von Vafai, Scott B, Mootha, Vamsi K

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Mitochondrial dysfunction remodels one-carbon metabolism in human cells von Bao, Xiaoyan Robert, Ong, Shao-En, Goldberger, Olga, Peng, Jun, Sharma, Rohit, Thompson, Dawn A, Vafai, Scott B, Cox, Andrew G, Marutani, Eizo, Ichinose, Fumito, Goessling, Wolfram, Regev, Aviv, Carr, Steven A, Clish, Clary B, Mootha, Vamsi K

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Regression of Drug-Resistant Lung Cancer by the Combination of Rosiglitazone and Carboplatin von Girnun, Geoffrey D, Chen, Liang, Silvaggi, Jessica, Drapkin, Ronny, Chirieac, Lucian, Padera, Robert, Upadhyay, Rabi, Vafai, Scott B, Weissleder, Ralph, Mahmood, Umar, Naseri, Elnaz, Buckley, Stephanie, Li, Danan, Force, Jeremy, McNamara, Kate, Demetri, George, Spiegelman, Bruce, Wong, Kwok-Kin

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Synergy between PPARgamma ligands and platinum-based drugs in cancer von Girnun, Geoffrey D, Naseri, Elnaz, Vafai, Scott B, Qu, Lishu, Szwaya, Jeffrey D, Bronson, Roderick, Alberta, John A, Spiegelman, Bruce M

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Mitochondrial disorders as windows into an ancient organelle von Vafai, Scott B, Mootha, Vamsi K

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