Transcriptome and metabolome analysis of crGART, a novel cell model of de novo purine synthesis deficiency: Alterations in CD36 expression and activity von Mazzarino, Randall C., Baresova, Veronika, Zikanova, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.

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Rapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging von Duval, Nathan, Vacano, Guido N, Patterson, David

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Reduced purine biosynthesis in humans after their divergence from Neandertals von Stepanova, Vita, Moczulska, Kaja Ewa, Vacano, Guido N., Kurochkin, Ilia, Ju, Xiangchun, Riesenberg, Stephan, Macak, Dominik, Maricic, Tomislav, Dombrowski, Linda, Schoernig, Maria, Anastassiadis, Konstantinos, Baker, Oliver, Naumann, Ronald, Khrameeva, Ekaterina, Vanushkina, Anna, Stekolshchikova, Elena, Egorova, Alina, Tkachev, Anna, Mazzarino, Randall, Duval, Nathan, Zubkov, Dmitri, Giavalisco, Patrick, Wilkinson, Terry G., Patterson, David, Khaitovich, Philipp, Paeaebo, Svante

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APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases von Perez-Corredor, Paula, Vanderleest, Timothy E, Vacano, Guido N, Sanchez, Justin S, Villalba-Moreno, Nelson D, Marino, Claudia, Krasemann, Susanne, Mendivil-Perez, Miguel A, Aguillón, David, Jiménez-Del-Río, Marlene, Baena, Ana, Sepulveda-Falla, Diego, Lopera, Francisco, Quiroz, Yakeel T, Arboleda-Velasquez, Joseph F, Mazzarino, Randall C

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The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model of ATIC deficiency and ZMP accumulation von Mazzarino, Randall C., Baresova, Veronika, Zikánová, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.

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The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation von Mazzarino, Randall C., Baresova, Veronika, Zikánová, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.

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Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: Cellular models of de novo purine biosynthesis deficiency disorders von Duval, Nathan, Luhrs, Kyleen, Wilkinson, Terry G., Baresova, Veronika, Skopova, Vaclava, Kmoch, Stanislav, Vacano, Guido N., Zikanova, Marie, Patterson, David

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The Use of Mouse Models for Understanding the Biology of Down Syndrome and Aging von Vacano, Guido N., Duval, Nathan, Patterson, David

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Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model von Vacano, Guido N., Gibson, David S., Turjoman, Abdullah Arif, Gawryluk, Jeremy W., Geiger, Jonathan D., Duncan, Mark, Patterson, David

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Assessment of post-mortem-induced changes to the mouse brain proteome von Hunsucker, Stephen W, Solomon, Benjamin, Gawryluk, Jeremy, Geiger, Jonathan D, Vacano, Guido N, Duncan, Mark W, Patterson, David

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