The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus von Oliveira, João J, Karrar, Sarah, Rainbow, Daniel B, Pinder, Christopher L, Clarke, Pamela, Rubio García, Arcadio, Al-Assar, Osama, Burling, Keith, Morris, Sian, Stratton, Richard, Vyse, Tim J, Wicker, Linda S, Todd, John A, Ferreira, Ricardo C

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A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC von Gregory, Simon, Carrington, Mary, Green, Todd, de Bakker, Paul I W, Beck, Stephan, Morrison, Jonathan, Trowsdale, John, Sabeti, Pardis C, Monsuur, Alienke J, Gao, Xiaojiang, Hart, John, McVean, Gil, Wijmenga, Cisca, Ke, Xiayi, Miretti, Marcos M, Hafler, David A, Deloukas, Panos, Delgado, Marcos, Richardson, Angela, Galver, Luana, Whittaker, Pamela, Pericak-Vance, Margaret, Daly, Mark J, Marchini, Jonathan, Vyse, Tim J, Rioux, John D, Walsh, Emily C, Todd, John A, Murray, Sarah Shaw

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Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation von Graham, Deborah S. Cunninghame, Manku, Harinder, Wagner, Susanne, Reid, Julia, Timms, Kirsten, Gutin, Alexander, Lanchbury, Jerry S., Vyse, Tim J.

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Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression von Ferreira, Ricardo C., Castro Dopico, Xaquin, Oliveira, João J., Rainbow, Daniel B., Yang, Jennie H., Trzupek, Dominik, Todd, Sarah A., McNeill, Mhairi, Steri, Maristella, Orrù, Valeria, Fiorillo, Edoardo, Crouch, Daniel J. M., Pekalski, Marcin L., Cucca, Francesco, Tree, Tim I., Vyse, Tim J., Wicker, Linda S., Todd, John A.

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Osteoclast Differentiation Is Impaired in a Subgroup of SLE Patients and Correlates Inversely with Mycophenolate Mofetil Treatment von Fürnrohr, Barbara G, Rhodes, Benjamin, Munoz, Luis E, Weiß, Katrin, Vyse, Tim J, Schett, Georg

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Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity von Ferreira, Ricardo C., Simons, Henry Z., Thompson, Whitney S., Rainbow, Daniel B., Yang, Xin, Cutler, Antony J., Oliveira, Joao, Castro Dopico, Xaquin, Smyth, Deborah J., Savinykh, Natalia, Mashar, Meghavi, Vyse, Tim J., Dunger, David B., Baxendale, Helen, Chandra, Anita, Wallace, Chris, Todd, John A., Wicker, Linda S., Pekalski, Marcin L.

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Lupus nephritis susceptibility loci in women with systemic lupus erythematosus von Chung, Sharon A, Brown, Elizabeth E, Williams, Adrienne H, Ramos, Paula S, Berthier, Celine C, Bhangale, Tushar, Alarcon-Riquelme, Marta E, Behrens, Timothy W, Criswell, Lindsey A, Graham, Deborah Cunninghame, Demirci, F Yesim, Edberg, Jeffrey C, Gaffney, Patrick M, Harley, John B, Jacob, Chaim O, Kamboh, M Ilyas, Kelly, Jennifer A, Manzi, Susan, Moser-Sivils, Kathy L, Russell, Laurie P, Petri, Michelle, Tsao, Betty P, Vyse, Tim J, Zidovetzki, Raphael, Kretzler, Matthias, Kimberly, Robert P, Freedman, Barry I, Graham, Robert R, Langefeld, Carl D

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Association of variation in Fcγ receptor 3B gene copy number with rheumatoid arthritis in Caucasian samples von McKinney, Cushla, Fanciulli, Manuela, Merriman, Marilyn E, Phipps-Green, Amanda, Alizadeh, Behrooz Z, Koeleman, Bobby P C, Dalbeth, Nicola, Gow, Peter J, Harrison, Andrew A, Highton, John, Jones, Peter B, Stamp, Lisa K, Steer, Sophia, Barrera, Pilar, Coenen, Marieke J H, Franke, Barbara, van Riel, Piet L C M, Vyse, Tim J, Aitman, Tim J, Radstake, Timothy R D J, Merriman, Tony R

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Understanding Lupus: Fishing Genes Out of Mice and Men von Vyse, Tim J.

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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4 von Manku, Harinder, Langefeld, Carl D, Guerra, Sandra G, Malik, Talat H, Alarcon-Riquelme, Marta, Anaya, Juan-Manuel, Bae, Sang-Cheol, Boackle, Susan A, Brown, Elizabeth E, Criswell, Lindsey A, Freedman, Barry I, Gaffney, Patrick M, Gregersen, Peter A, Guthridge, Joel M, Han, Sang-Hoon, Harley, John B, Jacob, Chaim O, James, Judith A, Kamen, Diane L, Kaufman, Kenneth M, Kelly, Jennifer A, Martin, Javier, Merrill, Joan T, Moser, Kathy L, Niewold, Timothy B, Park, So-Yeon, Pons-Estel, Bernardo A, Sawalha, Amr H, Scofield, R Hal, Shen, Nan, Stevens, Anne M, Sun, Celi, Gilkeson, Gary S, Edberg, Jeff C, Kimberly, Robert P, Nath, Swapan K, Tsao, Betty P, Vyse, Tim J

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FCGR3B copy number variation is associated with systemic lupus erythematosus risk in Afro-Caribbeans von Molokhia, Mariam, Fanciulli, Manuela, Petretto, Enrico, Patrick, Alan Leslie, McKeigue, Paul, Roberts, Amy L., Vyse, Tim J., Aitman, Tim J.

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A 4.6 kb genomic duplication on 20p12.2–12.3 is associated with brachydactyly type A2 in a Chinese family von Su, Peiqiang, Ding, Hongke, Huang, Dongsheng, Zhou, Yan, Huang, Weijun, Zhong, Liangying, Vyse, Tim J, Wang, Yiming

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Lupus podocytopathy von Shea-Simonds, Philip, Cairns, Tom D., Roufosse, Candice, Cook, Terry, Vyse, Tim J.

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TRAC Variants Associate with IgA Nephropathy von RU LI, CHAO XUE, VYSE, Tim J, LAI, Kar N, CHANGYOU WU, YIMING WANG, CAIXIA LI, TANQI LOU, YU TAO, YOUJI LI, WEIJUN HUANG, JUN ZHANG, LEUNG, Joseph C. K, LAM, Man F

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Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach von Rhodes, Benjamin, Morris, David L., Subrahmanyan, Lakshman, Aubin, Cristin, de Leon, Carlos F. Mendes, Kelly, Jeremiah F., Evans, Dennis A., Whittaker, John C., Oksenberg, Jorge R., De Jager, Philip L., Vyse, Tim J.

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Preview: Understanding Lupus: Fishing Genes Out of Mice and Men von Vyse, Tim J

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O47. SLE Susceptibility Gene UBE2L3 Polymorphism Controls Sensitivity of NF-KB to TNF and CD40 In Vivo von Lewis, Myles J., Vyse, Simon, Boeltz, Sebastian, Walczak, Henning, Spector, Tim D., Lehner, Paul J., Vyse, Tim J.

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Two Functional Lupus-Associated BLK Promoter Variants Control Cell-Type- and Developmental-Stage-Specific Transcription von Guthridge, Joel M., Lu, Rufei, Sun, Harry, Sun, Celi, Wiley, Graham B., Dominguez, Nicolas, Macwana, Susan R., Lessard, Christopher J., Kim-Howard, Xana, Cobb, Beth L., Kaufman, Kenneth M., Kelly, Jennifer A., Langefeld, Carl D., Adler, Adam J., Harley, Isaac T.W., Merrill, Joan T., Gilkeson, Gary S., Kamen, Diane L., Niewold, Timothy B., Brown, Elizabeth E., Edberg, Jeffery C., Petri, Michelle A., Ramsey-Goldman, Rosalind, Reveille, John D., Vilá, Luis M., Kimberly, Robert P., Freedman, Barry I., Stevens, Anne M., Boackle, Susan A., Criswell, Lindsey A., Vyse, Tim J., Behrens, Timothy W., Jacob, Chaim O., Alarcón-Riquelme, Marta E., Sivils, Kathy L., Choi, Jiyoung, Joo, Young Bin, Bang, So-Young, Lee, Hye-Soon, Bae, Sang-Cheol, Shen, Nan, Qian, Xiaoxia, Tsao, Betty P., Scofield, R. Hal, Harley, John B., Webb, Carol F., Wakeland, Edward K., James, Judith A., Nath, Swapan K., Graham, Robert R., Gaffney, Patrick M.

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FCGR3B copy number variation is associated with systemic lupus erythematosus risk in Afro-Caribbeans von Molokhia, Mariam, Fanciulli, Manuela, Petretto, Enrico, Patrick, Alan Leslie, McKeigue, Paul, Roberts, Amy L, Vyse, Tim J, Aitman, Tim J

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A 4.6 kb genomic duplication on 20p12.2-12.3 is associated with brachydactyly type A2 in a Chinese family : Copy-number variation von PEIQIANG SU, HONGKE DING, DONGSHENG HUANG, YAN ZHOU, WEIJUN HUANG, LIANGYING ZHONG, VYSE, Tim J, YIMING WANG

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