Investigating immune and non-immune cell interactions in head and neck tumors by single-cell RNA sequencing von Kürten, Cornelius H. L., Kulkarni, Aditi, Cillo, Anthony R., Santos, Patricia M., Roble, Anna K., Onkar, Sayali, Reeder, Carly, Lang, Stephan, Chen, Xueer, Duvvuri, Umamaheswar, Kim, Seungwon, Liu, Angen, Tabib, Tracy, Lafyatis, Robert, Feng, Jian, Gao, Shou-Jiang, Bruno, Tullia C., Vignali, Dario A. A., Lu, Xinghua, Bao, Riyue, Vujanovic, Lazar, Ferris, Robert L.

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Human B Cells Mediate Innate Anti-Cancer Cytotoxicity Through Concurrent Engagement of Multiple TNF Superfamily Ligands von Janjic, Bratislav M, Kulkarni, Aditi, Ferris, Robert L, Vujanovic, Lazar, Vujanovic, Nikola L

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Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment von Banerjee, Hridesh, Nieves-Rosado, Hector, Kulkarni, Aditi, Murter, Benjamin, McGrath, Kyle V., Chandran, Uma R., Chang, Alexander, Szymczak-Workman, Andrea L., Vujanovic, Lazar, Delgoffe, Greg M., Ferris, Robert L., Kane, Lawrence P.

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Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial von Ferris, Robert L, Spanos, William C, Leidner, Rom, Gonçalves, Anthony, Martens, Uwe M, Kyi, Chrisann, Sharfman, William, Chung, Christine H, Devriese, Lot A, Gauthier, Helene, Chiosea, Simon I, Vujanovic, Lazar, Taube, Janis M, Stein, Julie E, Li, Jun, Li, Bin, Chen, Tian, Barrows, Adam, Topalian, Suzanne L

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An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors von Chen, Xueer, Chen, Lujia, Kürten, Cornelius H L, Jabbari, Fattaneh, Vujanovic, Lazar, Ding, Ying, Lu, Binfeng, Lu, Kevin, Kulkarni, Aditi, Tabib, Tracy, Lafyatis, Robert, Cooper, Gregory F, Ferris, Robert, Lu, Xinghua

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Editorial: Cancer Immunotherapies: From Efficacy to Resistance Mechanisms von Chandra, Janin, Hansen, Morten, Labarriere, Nathalie, Marigo, Ilaria, Souza-Fonseca-Guimaraes, Fernando, Vujanovic, Lazar, Koguchi, Yoshinobu, Jacquelot, Nicolas

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Inhibition of Soluble Tumor Necrosis Factor Prevents Chemically Induced Carcinogenesis in Mice von Sobo-Vujanovic, Andrea, Vujanovic, Lazar, DeLeo, Albert B, Concha-Benavente, Fernando, Ferris, Robert L, Lin, Yan, Vujanovic, Nikola L

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Development of flow cytometry assays for measuring cell-membrane enzyme activity on individual cells von Gorry, Michael, Yoneyama, Toshie, Vujanovic, Lazar, Moss, Marcia L, Garlin, Michelle A, Miller, Miles A, Herman, James, Stabile, Laura P, Vujanovic, Nikola L

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Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors von Sander, Cindy A, Rush, Elizabeth A, Shi, Jian, Arantes, Lidia M R B, Tesi, Raymond J, Ross, Mark A, Calderon, Michael J, Watkins, Simon C, Kirkwood, John M, Ferris, Robert L, Butterfield, Lisa H, Vujanovic, Lazar

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PD-L1 Tumor Expression as a Predictive Biomarker of Immune Checkpoint Inhibitors' Response and Survival in Advanced Melanoma Patients in Brazil von Sorroche, Bruna Pereira, Teixeira, Renan de Jesus, Pereira, Caio Augusto Dantas, Santana, Iara Viana Vidigal, Vujanovic, Lazar, Vazquez, Vinicius de Lima, Arantes, Lidia Maria Rebolho Batista

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Differential impact of TIM-3 ligands on NK cell function von Wang, Juncheng, Li, Housaiyin, Kulkarni, Aditi, Anderson, Jennifer L, Upadhyay, Pragati, Onyekachi, Onyedikachi Victor, Arantes, Lidia M R B, Banerjee, Hridesh, Kane, Lawrence P, Zhang, Xin, Bruno, Tullia C, Bao, Riyue, Ferris, Robert L, Vujanovic, Lazar

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Multiple antigen-engineered DC vaccines with or without IFNα to promote antitumor immunity in melanoma von Butterfield, Lisa H, Vujanovic, Lazar, Santos, Patricia M, Maurer, Deena M, Gambotto, Andrea, Lohr, Joel, Li, Chunlei, Waldman, Jacob, Chandran, Uma, Lin, Yan, Lin, Huang, Tawbi, Hussein A, Tarhini, Ahmad A, Kirkwood, John M

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547 Reprogramming of type I interferon-responding tumor-reactive T lymphocytes associates with improved outcomes to neoadjuvant doublet immunotherapy in HNSCC von Li, Housaiyin, Santos, Patricia, Kulkarni, Aditi, Isett, Brian, Marion, Joy, Chiosea, Simon, Duvvuri, Uma, Kim, Seungwon, Kubik, Mark, Zandberg, Dan P, Bao, Riyue, Vujanovic, Lazar, Ferris, Robert

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1003 TIM-3+ natural killer cell dysfunction is driven by galectin-9 in head and neck squamous cell carcinoma von Wang, Juncheng, Li, Housaiyin, Kulkarni, Aditi, Anderson, Jennifer, Arantes, Lidia, Banerjee, Hridesh, Kane, Lawrence P, Zhang, Xin, Bruno, Tullia, Bao, Riyue, Ferris, Robert, Vujanovic, Lazar

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Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10 von Vujanovic, Lazar, Ballard, Wenners, Thorne, Stephen H., Vujanovic, Nikola L., Butterfield, Lisa H.

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CD56dim CD16− Natural Killer Cell Profiling in Melanoma Patients Receiving a Cancer Vaccine and Interferon-α von Vujanovic, Lazar, Chuckran, Christopher, Lin, Yan, Ding, Fei, Sander, Cindy A., Santos, Patricia M., Lohr, Joel, Mashadi-Hossein, Afshin, Warren, Sarah, White, Andy, Huang, Alan, Kirkwood, John M., Butterfield, Lisa H.

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Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment von Ruffin, Ayana T., Li, Housaiyin, Vujanovic, Lazar, Zandberg, Dan P., Ferris, Robert L., Bruno, Tullia C.

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756 Assessment of the immune checkpoint landscape in head and neck squamous cell carcinoma by single-cell RNA sequencing and multispectral imaging von Vujanovic, Lazar, Kulkarni, Aditi, Kürten, Cornelius, Cillo, Anthony, Santos, Patricia, Lang, Stephan, Duvvuri, Uma, Kim, Seungwon, Skinner, Heath, Bruno, Tullia, Vignali, Dario, Bao, Riyue, Ferris, Robert

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Tumor-derived alpha fetoprotein directly impacts human natural killer cell activity and viability von Vujanovic, Lazar, Stahl, Elizabeth, Pardee, Angela, Watkins, Simon, Gibson, Gregory, Butterfield, Lisa H

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Sheddase Activity of Tumor Necrosis Factor-α Converting Enzyme Is Increased and Prognostically Valuable in Head and Neck Cancer von Ge, Lisheng, Baskic, Dejan, Basse, Per, Vujanovic, Lazar, Unlu, Sebnem, Yoneyama, Toshie, Vujanovic, Andrea, Han, Jie, Bankovic, Dragic, Szczepanski, Miroslaw J, Hunt, Jennifer L, Herberman, Ronald B, Gollin, Susanne M, Ferris, Robert L, Whiteside, Theresa L, Myers, Eugene N, Vujanovic, Nikola L

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