CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin’s Lymphoma von Advani, Ranjana, Flinn, Ian, Popplewell, Leslie, Forero, Andres, Bartlett, Nancy L, Ghosh, Nilanjan, Kline, Justin, Roschewski, Mark, LaCasce, Ann, Collins, Graham P, Tran, Thu, Lynn, Judith, Chen, James Y, Volkmer, Jens-Peter, Agoram, Balaji, Huang, Jie, Majeti, Ravindra, Weissman, Irving L, Takimoto, Chris H, Chao, Mark P, Smith, Sonali M

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Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies von Chao, Mark P, Takimoto, Chris H, Feng, Dong Dong, McKenna, Kelly, Gip, Phung, Liu, Jie, Volkmer, Jens-Peter, Weissman, Irving L, Majeti, Ravindra

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Anti-CD47 antibody–mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response von Tseng, Diane, Volkmer, Jens-Peter, Willingham, Stephen B., Contreras-Trujillo, Humberto, Fathman, John W., Fernhoff, Nathaniel B., Seita, Jun, Inlay, Matthew A., Weiskopf, Kipp, Miyanishi, Masanori, Weissman, Irving L.

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Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk von Feng, Mingye, Chen, James Y., Weissman-Tsukamoto, Rachel, Volkmer, Jens-Peter, Ho, Po Yi, McKenna, Kelly M., Cheshier, Samuel, Zhang, Michael, Guo, Nan, Gip, Phung, Mitra, Siddhartha S., Weissman, Irving L.

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CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer von Cheah, Ming T., Chen, James Y., Sahoo, Debashis, Contreras-Trujillo, Humberto, Volkmer, Anne K., Scheeren, Ferenc A., Volkmer, Jens-Peter, Weissman, Irving L.

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CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis von Kojima, Yoko, Volkmer, Jens-Peter, McKenna, Kelly, Civelek, Mete, Lusis, Aldons Jake, Miller, Clint L., Direnzo, Daniel, Nanda, Vivek, Ye, Jianqin, Connolly, Andrew J., Schadt, Eric E., Quertermous, Thomas, Betancur, Paola, Maegdefessel, Lars, Matic, Ljubica Perisic, Hedin, Ulf, Weissman, Irving L., Leeper, Nicholas J.

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Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma von Edris, Badreddin, Weiskopf, Kipp, Volkmer, Anne K, Volkmer, Jens-Peter, Willingham, Stephen B, Contreras-Trujillo, Humberto, Liu, Jie, Majeti, Ravindra, West, Robert B, Fletcher, Jonathan A, Beck, Andrew H, Weissman, Irving L, van de Rijn, Matt

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Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity von Ring, Nan Guo, Herndler-Brandstetter, Dietmar, Weiskopf, Kipp, Shan, Liang, Volkmer, Jens-Peter, George, Benson M., Lietzenmayer, Melanie, McKenna, Kelly M., Naik, Tejaswitha J., McCarty, Aaron, Zheng, Yunjiang, Ring, Aaron M., Flavell, Richard A., Weissman, Irving L.

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Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential von Liu, Jie, Wang, Lijuan, Zhao, Feifei, Tseng, Serena, Narayanan, Cyndhavi, Shura, Lei, Willingham, Stephen, Howard, Maureen, Prohaska, Susan, Volkmer, Jens, Chao, Mark, Weissman, Irving L, Majeti, Ravindra

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CD47-Targeted Near-Infrared Photoimmunotherapy for Human Bladder Cancer von Kiss, Bernhard, van den Berg, Nynke S, Ertsey, Robert, McKenna, Kelly, Mach, Kathleen E, Zhang, Chiyuan Amy, Volkmer, Jens-Peter, Weissman, Irving L, Rosenthal, Eben L, Liao, Joseph C

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Engineered SIRPα Variants as Immunotherapeutic Adjuvants to Anticancer Antibodies von Weiskopf, Kipp, Ring, Aaron M., Ho, Chia Chi M., Volkmer, Jens-Peter, Levin, Aron M., Volkmer, Anne Kathrin, Özkan, Engin, Fernhoff, Nathaniel B., van de Rijn, Matt, Weissman, Irving L., Garcia, K. Christopher

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Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance von Upton, Rosalynd, Banuelos, Allison, Feng, Dongdong, Biswas, Tanuka, Kao, Kevin, McKenna, Kelly, Willingham, Stephen, Ho, Po Yi, Rosental, Benyamin, Tal, Casp Michali, Raveh, Tal, Volkmer, Jens-Peter, Pegram, Mark D., Weissman, Irving L.

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First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers von Sikic, Branimir I, Lakhani, Nehal, Patnaik, Amita, Shah, Sumit A, Chandana, Sreenivasa R, Rasco, Drew, Colevas, A Dimitrios, O'Rourke, Timothy, Narayanan, Sujata, Papadopoulos, Kyriakos, Fisher, George A, Villalobos, Victor, Prohaska, Susan S, Howard, Maureen, Beeram, Muralidhar, Chao, Mark P, Agoram, Balaji, Chen, James Y, Huang, Jie, Axt, Matthew, Liu, Jie, Volkmer, Jens-Peter, Majeti, Ravindra, Weissman, Irving L, Takimoto, Chris H, Supan, Dana, Wakelee, Heather A, Aoki, Rhonda, Pegram, Mark D, Padda, Sukhmani K

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An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells von Weissman, Irving L, Drukker, Micha, Tang, Chad, Lee, Andrew S, Volkmer, Jens-Peter, Sahoo, Debashis, Nag, Divya, Mosley, Adriane R, Inlay, Matthew A, Ardehali, Reza, Chavez, Shawn L, Pera, Renee Reijo, Behr, Barry, Wu, Joseph C

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Three differentiation states risk-stratify bladder cancer into distinct subtypes von Volkmer, Jens-Peter, Sahoo, Debashis, Chin, Robert K., Ho, Philip Levy, Tang, Chad, Kurtova, Antonina V., Willingham, Stephen B., Pazhanisamy, Senthil K., Contreras-Trujillo, Humberto, Storm, Theresa A., Lotan, Yair, Beck, Andrew H., Chung, Benjamin I., Alizadeh, Ash A., Godoy, Guilherme, Lerner, Seth P., van de Rijn, Matt, Shortliffe, Linda D., Weissman, Irving L., Chan, Keith S.

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A cell-intrinsic role for TLR2–MYD88 in intestinal and breast epithelia and oncogenesis von Scheeren, Ferenc A., Kuo, Angera H., van Weele, Linda J., Cai, Shang, Glykofridis, Iris, Sikandar, Shaheen S., Zabala, Maider, Qian, Dalong, Lam, Jessica S., Johnston, Darius, Volkmer, Jens P., Sahoo, Debashis, van de Rijn, Matt, Dirbas, Frederick M., Somlo, George, Kalisky, Tomer, Rothenberg, Michael E., Quake, Stephen R., Clarke, Michael F.

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Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors von Krampitz, Geoffrey Wayne, George, Benson M., Willingham, Stephen B., Volkmer, Jens-Peter, Weiskopf, Kipp, Jahchan, Nadine, Newman, Aaron M., Sahoo, Debashis, Zemek, Allison J., Yanovsky, Rebecca L., Nguyen, Julia K., Schnorr, Peter J., Mazur, Pawel K., Sage, Julien, Longacre, Teri A., Visser, Brendan C., Poultsides, George A., Norton, Jeffrey A., Weissman, Irving L.

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Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth von Edris, Badreddin, Willingham, Stephen B., Weiskopf, Kipp, Volkmer, Anne K., Volkmer, Jens-Peter, Mühlenberg, Thomas, Montgomery, Kelli D., Contreras-Trujillo, Humberto, Czechowicz, Agnieszka, Fletcher, Jonathan A., West, Robert B., Weissman, Irving L., van de Rijn, Matt

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CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors von Willingham, Stephen B, Volkmer, Jens-Peter, Gentles, Andrew J, Sahoo, Debashis, Dalerba, Piero, Mitra, Siddhartha S, Wang, Jian, Contreras-Trujillo, Humberto, Martin, Robin, Cohen, Justin D, Lovelace, Patricia, Scheeren, Ferenc A, Chao, Mark P, Weiskopf, Kipp, Tang, Chad, Volkmer, Anne Kathrin, Naik, Tejaswitha J, Storm, Theresa A, Mosley, Adriane R, Edris, Badreddin, Schmid, Seraina M, Sun, Chris K, Chua, Mei-Sze, Murillo, Oihana, Rajendran, Pradeep, Cha, Adriel C, Chin, Robert K, Kim, Dongkyoon, Adorno, Maddalena, Raveh, Tal, Tseng, Diane, Jaiswal, Siddhartha, Enger, Per Øyvind, Steinberg, Gary K, Li, Gordon, So, Samuel K, Majeti, Ravindra, Harsh, Griffith R, van de Rijn, Matt, Teng, Nelson N. H, Sunwoo, John B, Alizadeh, Ash A, Clarke, Michael F, Weissman, Irving L

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Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy von Liu, Jie, Xavy, Seethu, Mihardja, Shirley, Chen, Sharline, Sompalli, Kavitha, Feng, Dongdong, Choi, Timothy, Agoram, Balaji, Majeti, Ravindra, Weissman, Irving L, Volkmer, Jens-Peter

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