Folate-Conjugated Rapamycin Slows Progression of Polycystic Kidney Disease von SHILLINGFORD, Jonathan M, LEAMON, Christopher P, VLAHOV, Lontcho R, WEIMBS, Thomas

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Evaluation of Disulfide Reduction during Receptor-Mediated Endocytosis by Using FRET Imaging von Yang, Jun, Chen, Hongtao, Vlahov, Iontcho R., Cheng, Ji-Xin, Low, Philip S.

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Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic von Reddy, Joseph A., Dorton, Ryan, Bloomfield, Alicia, Nelson, Melissa, Dircksen, Christina, Vetzel, Marilynn, Kleindl, Paul, Santhapuram, Hari, Vlahov, Iontcho R., Leamon, Christopher P.

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Pre-clinical studies of EC2629, a highly potent folate- receptor-targeted DNA crosslinking agent von Reddy, Joseph A., Nelson, Melissa, Dircksen, Christina, Vetzel, Marilynn, Johnson, Theresa, Cross, Vicky, Westrick, Elaine, Qi, LongWu, Hahn, Spencer, Santhapuram, Hari Krishna, Parham, Garth, Wang, Kevin, Vaughn, Jeremy F., Felten, Albert, Pugh, Michael, Lu, June, Klein, Patrick, Vlahov, Iontcho R., Leamon, Christopher P.

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Preclinical evaluation of EC145, a folate-Vinca alkaloid conjugate von REDDY, Joseph A, DORTON, Ryan, WESTRICK, Elaine, DAWSON, Alicia, SMITH, Terri, XU, Le-Cun, VETZEL, Marilynn, KLEINDL, Paul, VLAHOV, Iontcho R, LEAMON, Christopher P

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Targeting Folate Receptors to Treat Invasive Urinary Bladder Cancer von DHAWAN, Deepika, RAMOS-VARA, Jose A, REDDY, Joseph A, KOCH, Michael, MURPHY, Linda, FOUREZ, Lindsey M, STEWART, Jane C, KNAPP, Deborah W, NAUGHTON, James F, LIANG CHENG, LOW, Philip S, ROTHENBUHLER, Ryan, LEAMON, Christopher P, PARKER, Nikki, KLEIN, Patrick J, VLAHOV, Lontcho R

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Comparative preclinical activity of the folate‐targeted Vinca alkaloid conjugates EC140 and EC145 von Leamon, Christopher P., Reddy, Joseph A., Vlahov, Iontcho R., Westrick, Elaine, Parker, Nikki, Nicoson, Jeffrey S., Vetzel, Marilynn

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Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide von Vlahov, Iontcho R., Santhapuram, Hari Krishna R., Kleindl, Paul J., Howard, Stephen J., Stanford, Katheryn M., Leamon, Christopher P.

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Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate von Lu, Yingjuan, Stinnette, Torian W, Westrick, Elaine, Klein, Patrick J, Gehrke, Mark A, Cross, Vicky A, Vlahov, Iontcho R, Low, Philip S, Leamon, Christopher P

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Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes von Lu, Yingjuan J., Wheeler, Leroy W., Chu, Haiyan, Kleindl, Paul J., Pugh, Michael, You, Fei, Rao, Satish, Garcia, Gabriela, Wu, Henry Y., da Cunha, Andre P., Johnson, Richard, Westrick, Elaine, Cross, Vicky, Lloyd, Alex, Dircksen, Christina, Klein, Patrick J., Vlahov, Iontcho R., Low, Philip S., Leamon, Christopher P.

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Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate von Leamon, Christopher P, Reddy, Joseph A, Bloomfield, Alicia, Dorton, Ryan, Nelson, Melissa, Vetzel, Marilynn, Kleindl, Paul, Hahn, Spencer, Wang, Kevin, Vlahov, Iontcho R

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Engineering Folate–Drug Conjugates to Target Cancer: From Chemistry to Clinic von Vlahov, Iontcho R, Leamon, Christopher P

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Folate–Vinca Alkaloid Conjugates for Cancer Therapy: A Structure–Activity Relationship von Leamon, Christopher P, Vlahov, Iontcho R, Reddy, Joseph A, Vetzel, Marilynn, Santhapuram, Hari Krishna R, You, Fei, Bloomfield, Alicia, Dorton, Ryan, Nelson, Melissa, Kleindl, Paul, Vaughn, Jeremy F, Westrick, Elaine

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Synthesis and Biological Evaluation of EC72:  A New Folate-Targeted Chemotherapeutic von Leamon, Christopher P, Reddy, Joseph A, Vlahov, Iontcho R, Vetzel, Marilynn, Parker, Nikki, Nicoson, Jeffrey S, Xu, Le-Cun, Westrick, Elaine

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Design and synthesis of a folate-receptor targeted diazepine-ring-opened pyrrolobenzodiazepine prodrug conjugate von Vlahov, Iontcho R., Qi, Longwu, Santhapuram, Hari Krishna R., Felten, Albert, Parham, Garth L., Zou, Ning, Wang, Kevin, You, Fei, Vaughn, Jeremy F., Hahn, Spencer J., Klein, Hanna F., Kleindl, Paul J., Reddy, Joe, Reno, Dan, Nicoson, Jeff, Leamon, Christopher P.

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An Assembly Concept for the Consecutive Introduction of Unsymmetrical Disulfide Bonds:  Synthesis of a Releasable Multidrug Conjugate of Folic Acid von Vlahov, Iontcho R, Santhapuram, Hari Krishna R, Wang, Yu, Kleindl, Paul J, You, Fei, Howard, Stephen J, Westrick, Elaine, Reddy, Joseph A, Leamon, Christopher P

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Synthesis and Biological Evaluation of EC140:  A Novel Folate-Targeted Vinca Alkaloid Conjugate von Leamon, Christopher P, Reddy, Joseph A, Vlahov, Iontcho R, Kleindl, Paul J, Vetzel, Marilynn, Westrick, Elaine

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Detecting Functional and Accessible Folate Receptor Expression in Cancer and Polycystic Kidneys von Chu, Haiyan, Shillingford, Jonathan M, Reddy, Joseph A, Westrick, Elaine, Nelson, Melissa, Wang, Emilia Z, Parker, Nikki, Felten, Albert E, Vaughn, Jeremy F, Xu, Le-Cun, Lu, Yingjuan J, Vlahov, Iontcho R, Leamon, Christopher P

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Preclinical Antitumor Activity of a Novel Folate-Targeted Dual Drug Conjugate von Leamon, Christopher P, Reddy, Joseph A, Vlahov, Iontcho R, Westrick, Elaine, Dawson, Alicia, Dorton, Ryan, Vetzel, Marilynn, Santhapuram, Hari Krishna, Wang, Yu

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Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma von Szigetvari, Nicholas M, Dhawan, Deepika, Ramos-Vara, José A, Leamon, Christopher P, Klein, Patrick J, Ruple, A Audrey, Heng, Hock Gan, Pugh, Michael R, Rao, Satish, Vlahov, Iontcho R, Deshuillers, Pierre L, Low, Philip S, Fourez, Lindsey M, Cournoyer, Ashleigh M, Knapp, Deborah W

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