The Next Frontier: Translational Development of Ubiquitination, SUMOylation, and NEDDylation in Cancer von Pellegrino, Nicole E, Guven, Arcan, Gray, Kayleigh, Shah, Punit, Kasture, Gargi, Nastke, Maria-Dorothea, Thakurta, Anjan, Gesta, Stephane, Vishnudas, Vivek K, Narain, Niven R, Kiebish, Michael A

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Reduced expression of collagen VI alpha 3 (COL6A3) confers resistance to inflammation‐induced MCP1 expression in adipocytes von Gesta, Stephane, Guntur, Kalyani, Majumdar, Ishita Deb, Akella, Syamala, Vishnudas, Vivek K., Sarangarajan, Rangaprasad, Narain, Niven R.

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Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancer von Dadali, Tulin, Diers, Anne R., Kazerounian, Shiva, Muthuswamy, Senthil K., Awate, Pallavi, Ng, Ryan, Mogre, Saie, Spencer, Carrie, Krumova, Katerina, Rockwell, Hannah E., McDaniel, Justice, Chen, Emily Y., Gao, Fei, Diedrich, Karl T., Vemulapalli, Vijetha, Rodrigues, Leonardo O., Akmaev, Viatcheslav R., Thapa, Khampaseuth, Hidalgo, Manuel, Bose, Arindam, Vishnudas, Vivek K., Moser, A. James, Granger, Elder, Kiebish, Michael A., Gesta, Stephane, Narain, Niven R., Sarangarajan, Rangaprasad

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High levels of ubidecarenone (oxidized CoQ10) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma ver... von Sun, Jiaxin, Patel, Chirag B., Jang, Taichang, Merchant, Milton, Chen, Chen, Kazerounian, Shiva, Diers, Anne R., Kiebish, Michael A., Vishnudas, Vivek K., Gesta, Stephane, Sarangarajan, Rangaprasad, Narain, Niven R., Nagpal, Seema, Recht, Lawrence

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A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells von Yang, Jialiang, Hagen, Jacob, Guntur, Kalyani V, Allette, Kimaada, Schuyler, Sarah, Ranjan, Jyoti, Petralia, Francesca, Gesta, Stephane, Sebra, Robert, Mahajan, Milind, Zhang, Bin, Zhu, Jun, Houten, Sander, Kasarskis, Andrew, Vishnudas, Vivek K, Akmaev, Viatcheslav R, Sarangarajan, Rangaprasad, Narain, Niven R, Schadt, Eric E, Argmann, Carmen A, Tu, Zhidong

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Intrinsic Properties of Brown and White Adipocytes Have Differential Effects on Macrophage Inflammatory Responses von Guntur, Kalyani, Gesta, Stephane, Vishnudas, Vivek K., Narain, Niven R., Sarangarajan, Rangaprasad, Mogre, Saie, Shah, Chahan, Ranjan, Jyoti, Majumdar, Ishita Deb, Akella, Syamala, Phat, Sarah, Parameswaran, Pooja, Dowal, Louisa, Thapa, Khampaseuth

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Hsp90β knockdown in DIO mice reverses insulin resistance and improves glucose tolerance von Jing, Enxuan, Sundararajan, Pragalath, Majumdar, Ishita Deb, Hazarika, Suwagmani, Fowler, Samantha, Szeto, Angela, Gesta, Stephane, Mendez, Armando J, Vishnudas, Vivek K, Sarangarajan, Rangaprasad, Narain, Niven R

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Pathology is alleviated by doxycycline in a laminin-α2-null model of congenital muscular dystrophy von Girgenrath, Mahasweta, Beermann, Mary Lou, Vishnudas, Vivek K., Homma, Sachiko, Miller, Jeffrey Boone

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Integrated Metabolomics Assessment of Human Dried Blood Spots and Urine Strips von Drolet, Jeremy, Tolstikov, Vladimir, Williams, Brian A, Greenwood, Bennett P, Hill, Collin, Vishnudas, Vivek K, Sarangarajan, Rangaprasad, Narain, Niven R, Kiebish, Michael A

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Ubc1 turnover contributes to the spindle assembly checkpoint in Saccharomyces cerevisiae von Arsenault, Heather E, Ghizzoni, Julie M, Leech, Cassandra M, Diers, Anne R, Gesta, Stephane, Vishnudas, Vivek K, Narain, Niven R, Sarangarajan, Rangaprasad, Benanti, Jennifer A

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Bayesian Model Infers Drug Repurposing Candidates for Treatment of COVID-19 von Kiebish, Michael A., Shah, Punit, Sarangarajan, Rangaprasad, Vishnudas, Vivek K., Gesta, Stephane, Tekumalla, Poornima K., Bountra, Chas, Granger, Elder, Schadt, Eric, Rodrigues, Leonardo O., Narain, Niven R.

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Dysregulation of the calcium handling protein, CCDC47, is associated with diabetic cardiomyopathy von Thapa, Khampaseuth, Wu, Kai Connie, Sarma, Aishwarya, Grund, Eric M, Szeto, Angela, Mendez, Armando J, Gesta, Stephane, Vishnudas, Vivek K, Narain, Niven R, Sarangarajan, Rangaprasad

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exceptionally fast actomyosin reaction powers insect flight muscle von Swank, D.M, Vishnudas, V.K, Maughan, D.W

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Identification of Filamin-A and -B as potential biomarkers for prostate cancer von Narain, Niven R, Diers, Anne R, Lee, Arleide, Lao, Socheata, Chan, Joyce Y, Schofield, Sally, Andreazi, Joe, Ouro-Djobo, Rakibou, Jimenez, Joaquin J, Friss, Tracey, Tanna, Nikunj, Dalvi, Aditee, Wang, Sihe, Bunch, Dustin, Sun, Yezhou, Wu, Wenfang, Thapa, Khampaseuth, Gesta, Stephane, Rodrigues, Leonardo O, Akmaev, Viatcheslav R, Vishnudas, Vivek K, Sarangarajan, Rangaprasad

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Pathology is alleviated by doxycycline in a laminin- alpha 2-null model of congenital muscular dystrophy von Girgenrath, Mahasweta, Beermann, Mary Lou, Vishnudas, Vivek K, Homma, Sachiko, Miller, Jeffrey Boone

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Dynamic and temporal assessment of human dried blood spot MS/MSALL shotgun lipidomics analysis von Gao, Fei, McDaniel, Justice, Chen, Emily Y., Rockwell, Hannah E., Drolet, Jeremy, Vishnudas, Vivek K., Tolstikov, Vladimir, Sarangarajan, Rangaprasad, Narain, Niven R., Kiebish, Michael A.

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Abstract 1014: The anti-Warburg agent BPM 31510 arbitrates fatty acid metabolism in eliciting an anticancer response von Jambhekar, Bianca, Dadali, Tulin, Diers, Anne R., Gao, Fei, Rockwell, Hannah, Chen, Emily, Gesta, Stephane, Vishnudas, Vivek K., Kiebish, Michael A., Narain, Niven R., Sarangarajan, Rangaprasad

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Ku70 regulates Bax-mediated pathogenesis in laminin-α2-deficient human muscle cells and mouse models of congenital muscular dystrophy von Vishnudas, Vivek K., Miller, Jeffrey Boone

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Abstract 212: BPM 31510 synergizes gemcitabine efficacy in pancreatic adenocarcinoma via mechanism independent of its anti-Warburg influence on metabolism von Dadali, Tulin, Diers, Anne R., Ouro-Djobo, Rakib, Bourdelais, Justin, Benaim, Ezer, Jambhekar, Bianca, Walshe, Tony E., Vishnudas, Vivek K., Jimenez, Joaquin J., Sarangarajan, Rangaprasad, Narain, Niven R.

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Abstract 2929: Benchmarking targets from cancer models using causal inference based drug-target and phenotype identification (Interrogative Biology®) cross-validates “high-priority... von Rodrigues, Leonardo O., Zhang, Lixia, Tekumalla, Poornima, Gesta, Stephane, Vishnudas, Vivek K., Kiebish, Michael A., Narain, Niven R., Sarangarajan, Rangaprasad

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