In Search of a Novel Anti-HIV Drug:  Multidisciplinary Coordination in the Discovery of 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile... von Janssen, Paul A. J, Lewi, Paul J, Arnold, Eddy, Daeyaert, Frits, de Jonge, Marc, Heeres, Jan, Koymans, Luc, Vinkers, Maarten, Guillemont, Jérôme, Pasquier, Elisabeth, Kukla, Mike, Ludovici, Don, Andries, Koen, de Béthune, Marie-Pierre, Pauwels, Rudi, Das, Kalyan, Clark, Art D, Frenkel, Yulia Volovik, Hughes, Stephen H, Medaer, Bart, De Knaep, Fons, Bohets, Hilde, De Clerck, Fred, Lampo, Ann, Williams, Peter, Stoffels, Paul

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SYNOPSIS:  SYNthesize and OPtimize System in Silico von Vinkers, H. Maarten, de Jonge, Marc R, Daeyaert, Frederik F. D, Heeres, Jan, Koymans, Lucien M. H, van Lenthe, Joop H, Lewi, Paul J, Timmerman, Henk, Van Aken, Koen, Janssen, Paul A. J

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Synthesis of Novel Diarylpyrimidine Analogues and Their Antiviral Activity against Human Immunodeficiency Virus Type 1 von Guillemont, Jerome, Pasquier, Elisabeth, Palandjian, Patrice, Vernier, Daniel, Gaurrand, Sandrine, Lewi, Paul J, Heeres, Jan, de Jonge, Marc R, Koymans, Lucien M. H, Daeyaert, Frits F. D, Vinkers, Maarten H, Arnold, Eddy, Das, Kalyan, Pauwels, Rudi, Andries, Koen, de Béthune, Marie-Pierre, Bettens, Eva, Hertogs, Kurt, Wigerinck, Piet, Timmerman, Philip, Janssen, Paul A. J

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Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Hi... von Das, Kalyan, Clark, Arthur D, Lewi, Paul J, Heeres, Jan, de Jonge, Marc R, Koymans, Lucien M. H, Vinkers, H. Maarten, Daeyaert, Frederik, Ludovici, Donald W, Kukla, Michael J, De Corte, Bart, Kavash, Robert W, Ho, Chih Y, Ye, Hong, Lichtenstein, Mark. A, Andries, Koen, Pauwels, Rudi, de Béthune, Marie-Pierre, Boyer, Paul L, Clark, Patrick, Hughes, Stephen H, Janssen, Paul A. J, Arnold, Eddy

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A pharmacophore docking algorithm and its application to the cross-docking of 18 HIV-NNRTI's in their binding pockets von Daeyaert, Frits, de Jonge, Marc, Heeres, Jan, Koymans, Luc, Lewi, Paul, Vinkers, Maarten H., Janssen, Paul A.J.

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Structure Based Activity Prediction of HIV-1 Reverse Transcriptase Inhibitors von de Jonge, Marc R, Koymans, Lucien M. H, Vinkers, H. Maarten, Daeyaert, Frits F. D, Heeres, Jan, Lewi, Paul J, Janssen, Paul A. J

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An ant algorithm for the conformational analysis of flexible molecules von Daeyaert, Frits, De Jonge, Marc, Koymans, Luc, Vinkers, Maarten

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Design, Synthesis, and SAR of a Novel Pyrazinone Series with Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitory Activity von Heeres, Jan, de Jonge, Marc R, Koymans, Lucien M. H, Daeyaert, Frits F. D, Vinkers, Maarten, Van Aken, Koen J. A, Arnold, Eddy, Das, Kalyan, Kilonda, Amuri, Hoornaert, Georges J, Compernolle, Frans, Cegla, Marek, Azzam, Rasha A, Andries, Koen, de Béthune, Marie-Pierre, Azijn, Hilde, Pauwels, Rudi, Lewi, Paul J, Janssen, Paul A. J

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Ab Initio potential grid based docking: From High Performance Computing to In Silico Screening von de Jonge, Marc R, Vinkers, H Maarten, van Lenthe, Joop H, Daeyaert, Frits, Bush, Ian J, van Dam, Huub J J, Sherwood, Paul, Guest, Martyn F

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Long-Term Outcome of Patients with Multiple (≥ 3) Noninfected Transvenous Leads: A Clinical and Echocardiographic Study von DE COCK, CAREL C., VINKERS, MAARTEN, VAN CAMPE, LINDA C.M.C., VERHORST, PATRICK M.J., VISSER, GEES A.

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On the detection of multiple-binding modes of ligands to proteins, from biological, structural, and modeling data von Lewi, Paul J, de Jonge, Marc, Daeyaert, Frits, Koymans, Luc, Vinkers, Maarten, Heeres, Jan, Janssen, Paul A J, Arnold, Eddy, Das, Kalyan, Clark, Jr, Art D, Hughes, Stephen H, Boyer, Paul L, de Béthune, Marie-Pierre, Pauwels, Rudi, Andries, Koen, Kukla, Mike, Ludovici, Donald, De Corte, Bart, Kavash, Robert, Ho, Chih, Lewis, Paul J

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In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (... von Janssen, Paul A.J, Lewi, Paul J, Arnold, Eddy, Daeyaert, Frits, de Jonge, Marc, Heeres, Jan, Koymans, Luc, Vinkers, Maarten, Guillemont, Jérôme, Pasquier, Elisabeth, Kukla, Mike, Ludovici, Don, Andries, Koen, de Béthune, Marie-Pierre, Pauwels, Rudi, Das, Kalyan, Clark, Art D, Frenkel, Yulia Volovik, Hughes, Stephen H, Medaer, Bart, De Knaep, Fons, Bohets, Hilde, De Clerck, Fred, Lampo, Ann, Williams, Peter, Stoffels, Paul

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Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1 von Guillemont, Jerome, Pasquier, Elisabeth, Palandjian, Patrice, Vernier, Daniel, Gaurrand, Sandrine, Lewi, Paul J, Heeres, Jan, de Jonge, Marc R, Koymans, Lucien M.H, Daeyaert, Frits F.D, Vinkers, Maarten H, Arnold, Eddy, Das, Kalyan, Pauwels, Rudi, Andries, Koen, de Béthune, Marie-Pierre, Bettens, Eva, Hertogs, Kurt, Wigerinck, Piet, Timmerman, Philip, Janssen, Paul A.J

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Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity von Heeres, Jan, de Jonge, Marc R, Koymans, Lucien M.H, Daeyaert, Frits F.D, Vinkers, Maarten, Van Aken, Koen J.A, Arnold, Eddy, Das, Kalyan, Kilonda, Amuri, Hoornaert, Georges, Compernolle, Frans, Cegla, Marek, Azzam, Rasha A, Andries, Koen, de Béthune, Marie-Pierre, Azijn, Hilde, Pauwels, Rudi, Lewi, Paul J, Janssen, Paul A.J

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PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION von MARC RENE DE JONGE, JEROME EMILE GEORGES GUILLEMONT, ELISABETH THERESE JEANNE PASQUIER, JAN HEERES, PAUL ADRIAAN JAN JANSSEN, LUCIEN MARIA HENRICUS KOYMANS, PAULUS JOANNES LEWI, FREDERIK FRANS DESIRE DAEYAERT, HENDRIK MAARTEN VINKERS

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Correlations between factors determining the pharmacokinetics and antiviral activity of HIV-1 non-nucleoside reverse transcriptase inhibitors of the diaryltriazine and diarylpyrimi... von Lewi, Paul, Arnold, Eddy, Andries, Koen, Bohets, Hilde, Borghys, Herman, Clark, Arthur, Daeyaert, Frits, Das, Kalyan, de Béthune, Marie-Pierre, de Jonge, Marc, Heeres, Jan, Koymans, Luc, Leempoels, Jos, Peeters, Jef, Timmerman, Philip, Van den Broeck, Walter, Vanhoutte, Frédéric, Van't Klooster, Gerben, Vinkers, Maarten, Volovik, Yulia, Janssen, Paul A J

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Ab initio calculations on iron-porphyrin model systems for intermediates in the oxidative cycle of cytochrome P450s von de Groot, M J, Havenith, R W, Vinkers, H M, Zwaans, R, Vermeulen, N P, van Lenthe, J H

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Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are hi... von Das, Kalyan, Clark, Arthur D, Lewi, Paul J, Heeres, Jan, De Jonge, Marc R, Koymans, Lucien M.H, Vinkers, H. Maarten, Daeyaert, Frederik, Ludovici, Donald W, Kukla, Michael J, De Corte, Bart, Kavash, Robert W, Ho, Chih Y, Ye, Hong, Lichtenstein, Mark A, Andries, Koen, Pauwels, Rudi, De Béthune, Marie-Pierre, Boyer, Paul L, Clark, Patrick, Hughes, Stephen H, Janssen, Paul A.J, Arnold, Eddy

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Composição farmacêutica compreendendo derivados de pirimidina que inibem o hiv von JEROME EMILE GEORGES GUILLEMONT, KOEN JEANNE ALFONS VAN AKEN, MARC RENEDE JONGE, HEERES JAN, PALANDJIAN PATRICE, LUCIEN MARIA HENRICUS KOYMANS, PAUL ADRIAAN JAN JANSSEN, PAULUS JOANNES LEWI, FREDERIK FRANS DESIRE DAEYAERT, HENDRIK MAARTEN VINKERS

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HIV REPLICATION INHIBITING PYRIMIDINES von Heeres Jan, Vinkers Hendrik Maarten, Janssen Paul Adriaan Jan, Koymans Lucien Maria Henricus, Van Aken Koen Jeanne Alfons, de Jonge Marc Rene, Palandijan Patrice, Daeyaert Frederik Frans Desire, Lewi Paulus Joannes, Guillemont Jerome Emile Georges

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