Sugar phosphate activation of the stress sensor eIF2B von Hao, Qi, Heo, Jin-Mi, Nocek, Boguslaw P., Hicks, Kevin G., Stoll, Vincent S., Remarcik, Clint, Hackett, Sean, LeBon, Lauren, Jain, Rinku, Eaton, Dan, Rutter, Jared, Wong, Yao Liang, Sidrauski, Carmela

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Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding von Huerta, Carlos, Jiang, Xin, Trevino, Isaac, Bender, Christopher F., Ferguson, Deborah A., Probst, Brandon, Swinger, Kerren K., Stoll, Vincent S., Thomas, Philip J., Dulubova, Irina, Visnick, Melean, Wigley, W. Christian

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Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site von Goedken, Eric R., Argiriadi, Maria A., Dietrich, Justin D., Petros, Andrew M., Krishnan, Navasona, Panchal, Sanjay C., Qiu, Wei, Wu, Haihong, Zhu, Haizhong, Adams, Ashley M., Bodelle, Pierre M., Goguen, Lucas, Richardson, Paul L., Slivka, Peter F., Srikumaran, Myron, Upadhyay, Anup K., Wu, Bainan, Judge, Russell A., Vasudevan, Anil, Gopalakrishnan, Sujatha M., Cox, Philip B., Stoll, Vincent S., Sun, Chaohong

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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo von Luo, Yan, Shoemaker, Alexander R, Liu, Xuesong, Woods, Keith W, Thomas, Sheela A, de Jong, Ron, Han, Edward K, Li, Tongmei, Stoll, Vincent S, Powlas, Jessica A, Oleksijew, Anatol, Mitten, Michael J, Shi, Yan, Guan, Ran, McGonigal, Thomas P, Klinghofer, Vered, Johnson, Eric F, Leverson, Joel D, Bouska, Jennifer J, Mamo, Mulugeta, Smith, Richard A, Gramling-Evans, Emily E, Zinker, Bradley A, Mika, Amanda K, Nguyen, Phong T, Oltersdorf, Tilman, Rosenberg, Saul H, Li, Qun, Giranda, Vincent L

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Cryo-EM structure of human PAPP-A2 and mechanism of substrate recognition von Sridar, Janani, Mafi, Amirhossein, Judge, Russell A., Xu, Jun, Kong, Kailyn A., Wang, John C. K., Stoll, Vincent S., Koukos, Georgios, Simon, Reyna J., Eaton, Dan, Bratkowski, Matthew, Hao, Qi

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Mechanistic insights into a heterobifunctional degrader-induced PTPN2/N1 complex von Hao, Qi, Rathinaswamy, Manoj K., Klinge, Kelly L., Bratkowski, Matthew, Mafi, Amirhossein, Baumgartner, Christina K., Hamel, Keith M., Veits, Gesine K., Jain, Rinku, Catalano, Claudio, Fitzgerald, Mark, Hird, Alexander W., Park, Eunice, Vora, Harit U., Henderson, James A., Longenecker, Kenton, Hutchins, Charles W., Qiu, Wei, Scapin, Giovanna, Sun, Qi, Stoll, Vincent S., Sun, Chaohong, Li, Ping, Eaton, Dan, Stokoe, David, Fisher, Stewart L., Nasveschuk, Christopher G., Paddock, Marcia, Kort, Michael E.

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Accelerating pharmaceutical structure-guided drug design: a successful model von Keefe, Lisa J., Stoll, Vincent S.

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A potent erythropoietin-mimicking human antibody interacts through a novel binding site von Liu, Zhihong, Stoll, Vincent S., DeVries, Peter J., Jakob, Clarissa G., Xie, Nancy, Simmer, Robert L., Lacy, Susan E., Egan, David A., Harlan, John E., Lesniewski, Richard R., Reilly, Edward B.

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Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design von Dietrich, Justin D, Longenecker, Kenton L, Wilson, Noel S, Goess, Christian, Panchal, Sanjay C, Swann, Steven L, Petros, Andrew M, Hobson, Adrian D, Ihle, David, Song, Danying, Richardson, Paul, Comess, Kenneth M, Cox, Philip B, Dombrowski, Amanda, Sarris, Kathy, Donnelly-Roberts, Diana L, Duignan, David B, Gomtsyan, Arthur, Jung, Paul, Krueger, A Chris, Mathieu, Suzanne, McClure, Andrea, Stoll, Vincent S, Wetter, Jill, Mankovich, John A, Hajduk, Philip J, Vasudevan, Anil, Stoffel, Robert H, Sun, Chaohong

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Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer von Petros, Andrew M, Korepanova, Alla, Jakob, Clarissa G, Qiu, Wei, Panchal, Sanjay C, Wang, Jie, Dietrich, Justin D, Brewer, Jason T, Pohlki, Frauke, Kling, Andreas, Wilcox, Kyle, Lakics, Viktor, Bahnassawy, Lamiaa, Reinhardt, Peter, Partha, Sarathy Karunan, Bodelle, Pierre M, Lake, Marc, Charych, Erik I, Stoll, Vincent S, Sun, Chaohong, Mohler, Eric G

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Crystal Structures of DPP-IV (CD26) from Rat Kidney Exhibit Flexible Accommodation of Peptidase-Selective Inhibitors von Longenecker, Kenton L, Stewart, Kent D, Madar, David J, Jakob, Clarissa G, Fry, Elizabeth H, Wilk, Sherwin, Lin, Chun W, Ballaron, Stephen J, Stashko, Michael A, Lubben, Thomas H, Yong, Hong, Pireh, Daisy, Pei, Zhonghua, Basha, Fatima, Wiedeman, Paul E, von Geldern, Thomas W, Trevillyan, James M, Stoll, Vincent S

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Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment... von Li, Qun, Woods, Keith W., Thomas, Sheela, Zhu, Gui-Dong, Packard, Garrick, Fisher, John, Li, Tongmei, Gong, Jianchun, Dinges, Jurgen, Song, Xiaohong, Abrams, Jason, Luo, Yan, Johnson, Eric F., Shi, Yan, Liu, Xuesong, Klinghofer, Vered, Des Jong, Ron, Oltersdorf, Tilman, Stoll, Vincent S., Jakob, Clarissa G., Rosenberg, Saul H., Giranda, Vincent L.

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Novel α- and β-Amino Acid Inhibitors of Influenza Virus Neuraminidase von KATI, Warren M, MONTGOMERY, Debra, MARING, Clarence, STOLL, Vincent S, GIRANDA, Vincent, XIAOQI CHEN, LAVER, W. Graeme, KOHLBRENNER, William, NORBECK, Daniel W

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Discovery of N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N‘-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-Aminoindazole-Based Orally Active Multitargeted Receptor Tyrosine Kinase Inhibito... von Dai, Yujia, Hartandi, Kresna, Ji, Zhiqin, Ahmed, Asma A, Albert, Daniel H, Bauch, Joy L, Bouska, Jennifer J, Bousquet, Peter F, Cunha, George A, Glaser, Keith B, Harris, Christopher M, Hickman, Dean, Guo, Jun, Li, Junling, Marcotte, Patrick A, Marsh, Kennan C, Moskey, Maria D, Martin, Ruth L, Olson, Amanda M, Osterling, Donald J, Pease, Lori J, Soni, Niru B, Stewart, Kent D, Stoll, Vincent S, Tapang, Paul, Reuter, David R, Davidsen, Steven K, Michaelides, Michael R

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In Vitro Selection and Characterization of Influenza A (A/N9) Virus Variants Resistant to a Novel Neuraminidase Inhibitor, A-315675 von Molla, Akhteruzzaman, Kati, Warren, Carrick, Robert, Steffy, Kevin, Shi, Yan, Montgomery, Debra, Gusick, Nanette, Stoll, Vincent S, Stewart, Kent D, Ng, Teresa I, Maring, Clarence, Kempf, Dale J, Kohlbrenner, William

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Discovery of 3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective, and Orally Bioavailable Inhibitors of the Human Protooncogene Proviral Insertion Site in Molone... von Tao, Zhi-Fu, Hasvold, Lisa A, Leverson, Joel D, Han, Edward K, Guan, Ran, Johnson, Eric F, Stoll, Vincent S, Stewart, Kent D, Stamper, Geoff, Soni, Nirupama, Bouska, Jennifer J, Luo, Yan, Sowin, Thomas J, Lin, Nan-Horng, Giranda, Vincent S, Rosenberg, Saul H, Penning, Thomas D

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Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate von Judge, Russell A., Vasudevan, Anil, Scott, Victoria E., Simler, Gricelda H., Pratt, Steve D., Namovic, Marian T., Putman, C. Brent, Aguirre, Ana, Stoll, Vincent S., Mamo, Mulugeta, Swann, Steven I., Cassar, Steven C., Faltynek, Connie R., Kage, Karen L., Boyce‐Rustay, Janel M., Hobson, Adrian D.

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Corrigendum: Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate von Judge, Russell A., Vasudevan, Anil, Scott, Victoria E., Simler, Gricelda H., Pratt, Steve D., Namovic, Marian T., Putman, C. Brent, Aguirre, Ana, Stoll, Vincent S., Mamo, Mulugeta, Swann, Steven I., Cassar, Steven C., Faltynek, Connie R., Kage, Karen L., Boyce‐Rustay, Janel M., Hobson, Adrian D.

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Design and synthesis of pyridine–pyrazolopyridine-based inhibitors of protein kinase B/Akt von Zhu, Gui-Dong, Gong, Jianchun, Gandhi, Viraj B., Woods, Keith, Luo, Yan, Liu, Xuesong, Guan, Ran, Klinghofer, Vered, Johnson, Eric F., Stoll, Vincent S., Mamo, Mulugeta, Li, Qun, Rosenberg, Saul H., Giranda, Vincent L.

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Buffers: principles and practice von Stoll, Vincent S, Blanchard, John S

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