Systemic Administration of GPI 15427, a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, Increases the Antitumor Activity of Temozolomide against Intracranial Melanoma, Glioma, Lymph... von TENTORI, Lucio, LEONETTI, Carlo, GRAZIANI, Grazia, SCARSELLA, Marco, D'AMATI, Giulia, VERGATI, Matteo, PORTARENA, Ilaria, WEIZHENG XU, KALISH, Vincent, ZUPI, Gabriella, JIE ZHANG

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Viracept (Nelfinavir Mesylate, AG1343):  A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease von Kaldor, Stephen W, Kalish, Vincent J, Davies, Jay F, Shetty, Bhasker V, Fritz, James E, Appelt, Krzysztof, Burgess, Jeffrey A, Campanale, Kristina M, Chirgadze, Nickolay Y, Clawson, David K, Dressman, Bruce A, Hatch, Steven D, Khalil, Deborah A, Kosa, Maha B, Lubbehusen, Penny P, Muesing, Mark A, Patick, Amy K, Reich, Siegfried H, Su, Kenneth S, Tatlock, John H

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Synthesis of substituted 5[ H]phenanthridin-6-ones as potent poly(ADP-ribose)polymerase-1 (PARP1) inhibitors von Li, Jia-He, Serdyuk, Larisa, Ferraris, Dana V., Xiao, Ge, Tays, Kevin L., Kletzly, Paul W., Li, Weixing, Lautar, Susan, Zhang, Jie, Kalish, Vincent J.

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Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex von Kissinger, Charles R, Parge, Hans E, Knighton, Daniel R, Lewis, Cristina T, Pelletier, Laura A, Tempczyk, Anna, Kalish, Vincent J, Tucker, Kathleen D, Showalter, Richard E, Moomaw, Ellen W, Gastinel, Louis N, Habuka, Noriyuki, Chen, Xinghai, Maldonado, Fausto, Barker, John E, Bacquet, Russell, Villafranca, J. Ernest

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Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. part 4: Biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of isch... von Ferraris, Dana, Ficco, Rica Pargas, Dain, David, Ginski, Mark, Lautar, Susan, Lee-Wisdom, Kathy, Liang, Shi, Lin, Qian, Lu, May X.-C, Morgan, Lisa, Thomas, Bert, Williams, Lawrence R, Zhang, Jie, Zhou, Yinong, Kalish, Vincent J

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Design and Synthesis of Poly ADP-ribose Polymerase-1 Inhibitors. 2. Biological Evaluation of Aza-5[H]-phenanthridin-6-ones as Potent, Aqueous-Soluble Compounds for the Treatment of... von Ferraris, Dana, Ko, Yao-Sen, Pahutski, Thomas, Ficco, Rica Pargas, Serdyuk, Larisa, Alemu, Christina, Bradford, Chadwick, Chiou, Tiffany, Hoover, Randall, Huang, Shirley, Lautar, Susan, Liang, Shi, Lin, Qian, Lu, May X.-C, Mooney, Maria, Morgan, Lisa, Qian, Yongzhen, Tran, Scott, Williams, Lawrence R, Wu, Qi Yi, Zhang, Jie, Zou, Yinong, Kalish, Vincent

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Structure–activity relationships within a series of caspase inhibitors. Part 2: Heterocyclic warheads von Ullman, Brett R., Aja, Teresa, Chen, Ning, Diaz, Jose-Luis, Gu, Xin, Herrmann, Julia, Kalish, Vincent J., Karanewsky, Donald S., Kodandapani, Lalitha, Krebs, Joseph J., Linton, Steven D., Meduna, Steven P., Nalley, Kip, Robinson, Edward D., Roggo, Silvio P., Sayers, Robert O., Schmitz, Albert, Ternansky, Robert J., Tomaselli, Kevin J., Wu, Joe C.

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Structure-activity relationships within a series of caspase inhibitors: Effect of leaving group modifications von ULLMAN, Brett R, AJA, Teresa, ROGGO, Silvio P, SAYERS, Robert O, SCHMITZ, Albert, TERNANSKY, Robert J, TOMASELLI, Kevin J, WU, Joe C, DECKWERTH, Thomas L, DIAZ, Jose-Luis, HERRMANN, Julia, KALISH, Vincent J, KARANEWSKY, Donald S, MEDUNA, Steven P, NALLEY, Kip, ROBINSON, Edward D

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Acyl dipeptides as reversible caspase inhibitors. Part 2: Further optimization von LINTON, Steven D, KARANEWSKY, Donald S, WU, Joe C, PHAM, Brian, KODANDAPANI, Lalitha, SMIDT, Robert, DIAZ, Jose-Luis, FRITZ, Lawrence C, VON KROSIGK, U, ROGGO, Silvio, SCHMITZ, Albert, TOMASELLI, Kevin J, TERNANSKY, Robert J, NING CHEN, GUO, Xian, JAHANGIRI, Kathy G, KALISH, Vincent J, MEDUNA, Steven P, ROBINSON, Edward D, ULLMAN, Brett R

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First-in-Class Pan Caspase Inhibitor Developed for the Treatment of Liver Disease von Linton, Steven D, Aja, Teresa, Armstrong, Robert A, Bai, Xu, Chen, Long-Shiuh, Chen, Ning, Ching, Brett, Contreras, Patricia, Diaz, Jose-Luis, Fisher, Craig D, Fritz, Lawrence C, Gladstone, Patricia, Groessl, Todd, Gu, Xin, Herrmann, Julia, Hirakawa, Brad P, Hoglen, Niel C, Jahangiri, Kathy G, Kalish, Vincent J, Karanewsky, Donald S, Kodandapani, Lalitha, Krebs, Joseph, McQuiston, Jeff, Meduna, Steven P, Nalley, Kip, Robinson, Edward D, Sayers, Robert O, Sebring, Kristen, Spada, Alfred P, Ternansky, Robert J, Tomaselli, Kevin J, Ullman, Brett R, Valentino, Karen L, Weeks, Suzanne, Winn, David, Wu, Joe C, Yeo, Pauline, Zhang, Cheng-zhi

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Structure-Based Design of Novel, Urea-Containing FKBP12 Inhibitors von Dragovich, Peter S, Barker, John E, French, Judy, Imbacuan, Michael, Kalish, Vincent J, Kissinger, Charles R, Knighton, Daniel R, Lewis, Cristina T, Moomaw, Ellen W, Parge, Hans E, Pelletier, Laura A. K, Prins, Thomas J, Showalter, Richard E, Tatlock, John H, Tucker, Kathleen D, Villafranca, J. Ernest

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One-pot synthesis of protected prostaglandins from alkynes and cyclopentenones. In situ generation of higher order cyanocuprates derived from alkenylzirconium intermediates von Babiak, Kevin A, Behling, James R, Dygos, John H, McLaughlin, Kathleen T, Ng, John S, Kalish, Vincent J, Kramer, Steven W, Shone, Robert L

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Design and synthesis of poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors. Part 3: In vitro evaluation of 1,3,4,5-Tetrahydro-benzo[ c][1,6]- and [ c][1,7]-naphthyridin-6-ones von Ferraris, Dana, Ficco, Rica Pargas, Pahutski, Thomas, Lautar, Susan, Huang, Shirley, Zhang, Jie, Kalish, Vincent

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Ketopyrrolidines and ketoazetidines as potent dipeptidyl peptidase IV (DPP IV) inhibitors von Ferraris, Dana, Ko, Yao-Sen, Calvin, David, Chiou, Tiffany, Lautar, Susan, Thomas, Bert, Wozniak, Krystyna, Rojas, Camilo, Kalish, Vincent, Belyakov, Sergei

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Approaches to the total synthesis of the antitumor antibiotic echinosporin von Kinsella, Mary A, Kalish, Vincent J, Weinreb, Steven M

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NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX von Brookfield, Frederick Arthur, Frost, Lisa Marie, Toscano, John P, Kalish, Vincent Jacob, Courtney, Stephen Martin

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Nitroxyl donors with improved therapeutic index von Brookfield, Frederick Arthur, Frost, Lisa Marie, Toscano, John P, Kalish, Vincent Jacob, Courtney, Stephen Martin

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NITROXYL DONORS FOR THE TREATMENT OF PULMONARY HYPERTENSION von KALISH, Vincent J, MAZHARI, Reza

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NITROXYL DONORS FOR THE TREATMENT OF PULMONARY HYPERTENSION von KALISH, VINCENT J, MAZHARI, REZA

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NITROXYL DONORS FOR THE TREATMENT OF PULMONARY HYPERTENSION von KALISH VINCENT J, MAZHARI REZA

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