Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach von Wilson, Jonathan E, Kurukulasuriya, Ravi, Reibarkh, Mikhail, Reiter, Maud, Zwicker, Aaron, Zhao, Kake, Zhang, Fengqi, Anand, Rajan, Colandrea, Vincent J, Cumiskey, Anne-Marie, Crespo, Alejandro, Duffy, Ruth A, Murphy, Beth Ann, Mitra, Kaushik, Johns, Douglas G, Duffy, Joseph L, Vachal, Petr

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1,3,8-Triazaspiro[4.5]decane-2,4-diones as Efficacious Pan-Inhibitors of Hypoxia-Inducible Factor Prolyl Hydroxylase 1–3 (HIF PHD1–3) for the Treatment of Anemia von Vachal, Petr, Miao, Shouwu, Pierce, Joan M, Guiadeen, Deodial, Colandrea, Vincent J, Wyvratt, Matthew J, Salowe, Scott P, Sonatore, Lisa M, Milligan, James A, Hajdu, Richard, Gollapudi, Anantha, Keohane, Carol A, Lingham, Russell B, Mandala, Suzanne M, DeMartino, Julie A, Tong, Xinchun, Wolff, Michael, Steinhuebel, Dietrich, Kieczykowski, Gerard R, Fleitz, Fred J, Chapman, Kevin, Athanasopoulos, John, Adam, Gregory, Akyuz, Can D, Jena, Dhirendra K, Lusen, Jeffrey W, Meng, Juncai, Stein, Benjamin D, Xia, Lei, Sherer, Edward C, Hale, Jeffrey J

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Synthesis and evaluation of N-[(1 S,2 S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists von Du, Wu, Jewell, James P., Lin, Linus S., Colandrea, Vincent J., Xiao, Jing C., Lao, Julie, Shen, Chun-Pyn, Bateman, Thomas J., Reddy, Vijay B.G., Ha, Sookhee N., Shah, Shrenik K., Fong, Tung M., Hale, Jeffrey J., Hagmann, William K.

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Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia von Liu, Ping, Wang, Liping, DuBois, Byron G, Colandrea, Vincent J, Liu, Rongqiang, Cai, Jiaqiang, Du, Xiaoxing, Quan, Weiguo, Morris, William, Bai, Jianwu, Bishwokarma, Bimjhana, Cheng, Mangeng, Piesvaux, Jennifer, Ray, Kallol, Alpert, Carla, Chiu, Chi-Sung, Zielstorff, Mark, Metzger, Joseph M, Yang, Liming, Leung, Dennis, Alleyne, Candice, Vincent, Stella H, Pucci, Vincenzo, Li, Xiaofang, Crespo, Alejandro, Stickens, Dominique, Hale, Jeffrey J, Ujjainwalla, Feroze, Sinz, Christopher J

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Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor von Neelamkavil, Santhosh F, Agrawal, Sony, Bara, Thomas, Bennett, Chad, Bhat, Sathesh, Biswas, Dipshikha, Brockunier, Linda, Buist, Nicole, Burnette, Duane, Cartwright, Mark, Chackalamannil, Samuel, Chase, Robert, Chelliah, Mariappan, Chen, Austin, Clasby, Martin, Colandrea, Vincent J, Davies, Ian W, Eagen, Keith, Guo, Zhuyan, Han, Yongxin, Howe, John, Jayne, Charles, Josien, Hubert, Kargman, Stacia, Marcantonio, Karen, Miao, Shouwu, Miller, Randy, Nolting, Andrew, Pinto, Patrick, Rajagopalan, Murali, Ruck, Rebecca T, Shah, Unmesh, Soriano, Aileen, Sperbeck, Donald, Velazquez, Francisco, Wu, Jin, Xia, Yan, Venkatraman, Srikanth

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Synthesis of the Mitomycin and FR900482 Ring Systems via Dimethyldioxirane Oxidation von Colandrea, Vincent J, Rajaraman, Shanthi, Jimenez, Leslie S

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2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists von Colandrea, Vincent J., Legiec, Irene E., Huo, Pei, Yan, Lin, Hale, Jeffrey J., Mills, Sander G., Bergstrom, James, Card, Deborah, Chebret, Gary, Hajdu, Richard, Keohane, Carol Ann, Milligan, James A., Rosenbach, Mark J., Shei, Gan-Ju, Mandala, Suzanne M.

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Substituted acyclic sulfonamides as human cannabinoid-1 receptor inverse agonists von Armstrong, Helen E., Galka, Amy, Lin, Linus S., Lanza, Thomas J., Jewell, James P., Shah, Shrenik K., Guthikonda, Ravi, Truong, Quang, Chang, Linda L., Quaker, Grace, Colandrea, Vincent J., Tong, Xinchun, Wang, Junying, Xu, Sherry, Fong, Tung M., Shen, Chun-Pyn, Lao, Julie, Chen, Jing, Shearman, Lauren P., Stribling, D. Sloan, Rosko, Kimberly, Strack, Alison, Ha, Sookhee, der Ploeg, Lex Van, Goulet, Mark T., Hagmann, William K.

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Reactivity and rearrangements of dialkyl- and diarylvinylsulfonium salts with indole-2- and pyrrole-2-carboxaldehydes von Wang, Yufeng, Zhang, Weihong, Colandrea, Vincent J, Jimenez, Leslie S

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Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective β3 adrenergic receptor agonist antiobesity agents von BIFTU, T, FENG, D. D, FORREST, M. J, HOM, G. J, MACLNTYRE, D. E, STEARNS, R. A, STRADER, C. D, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, LIANG, G.-B, KUO, H, XIAOXIA QIAN, NAYLOR, E. M, COLANDREA, V. J, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F

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Composés de c-mannoside utiles pour le traitement d'infections des voies urinaires von COLANDREA, Vincent J, LI, Yuehu, STRAMBEANU, Iulia, STEWART, Eugene L, BISHOP, Michael Joseph, MCGRANE, Laurel Kathryn, JANETKA, James Walter, WIDDOWSON, Katherine Louisa

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Synthesis and regioselective alkylation of 1,6- and 1,7-naphthyridines von Colandrea, Vincent J, Naylor, Elizabeth M

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COMPOSÉS DE C-MANNOSIDE UTILES POUR LE TRAITEMENT D'INFECTIONS DES VOIES URINAIRES von COLANDREA, Vincent J, LI, Yuehu, STRAMBEANU, Iulia, BISHOP, Michael Joseph, MCGRANE, Laurel Kathryn, STEWART, Eugene L, JANETKA, James Walter, WIDDOWSON, Katherine Louisa

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Improved synthesis of aryl 1,1-dimethylpropargyl ethers von Godfrey, Jollie D., Mueller, Richard H., Sedergran, Thomas C., Soundararajan, Nachimuthu, Colandrea, Vincent J.

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Synthesis and evaluation of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyll-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists von WU DU, JEWELL, James P, SHAH, Shrenik K, FONG, Tung M, HALE, Jeffrey J, HAGMANN, William K, LIN, Linus S, COLANDREA, Vincent J, XIAO, Jing C, JULIE LAO, SHEN, Chun-Pyn, BATEMAN, Thomas J, REDDY, Vijay B. G, HA, Sookhee N

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C-MANNOSIDE COMPOPUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS von COLANDREA, Vincent J, LI, Yuehu, STRAMBEANU, Iulia, BISHOP, Michael Joseph, STEWART, Eugene L, MCGRANE, Laurel Kathryn, JANETKA, James Walter, WIDDOWSON, Katherine Louisa

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Human β3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides von NAYLOR, E. M, PARMEE, E. R, FORREST, M. J, HOM, G. J, MACINTYRE, D. E, STRADER, C. D, TOTA, L, WANG, P.-R, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, COLANDREA, V. J, PERKINS, L, BROCKUNIER, L, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F, LIPING DENG, FEENEY, W. P

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C-MANNOSIDE COMPOPUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS von COLANDREA, Vincent J, LI, Yuehu, STRAMBEANU, Iulia, BISHOP, Michael Joseph, STEWART, Eugene L, MCGRANE, Laurel Kathryn, JANETKA, James Walter, WIDDOWSON, Katherine Louisa

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C-MANNOSIDE COMPOUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS von Colandrea, Vincent J, McGrane, Laurel Kathryn, Strambeanu, Iulia, Bishop, Michael Joseph, Stewart, Eugene L, Widdowson, Katherine Louisa, Li, Yuehu, Janetka, James Walter

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C-MANNOSIDE COMPOPUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS von LI, YUEHU, MCGRANE, LAUREL KATHRYN, JANETKA, JAMES WALTER, STRAMBEANU, IULIA, STEWART, EUGENE L, COLANDREA, VINCENT J, BISHOP, MICHAEL JOSEPH, WIDDOWSON, KATHERINE LOUISA

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