Palladium-Catalyzed Direct Arylation of Azine and Azole N-Oxides: Reaction Development, Scope and Applications in Synthesis von Campeau, Louis-Charles, Stuart, David R., Leclerc, Jean-Philippe, Bertrand-Laperle, Mégan, Villemure, Elisia, Sun, Ho-Yan, Lasserre, Sandrine, Guimond, Nicolas, Lecavallier, Melanie, Fagnou, Keith

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Elements of Regiocontrol in Palladium-Catalyzed Oxidative Arene Cross-Coupling von Stuart, David R, Villemure, Elisia, Fagnou, Keith

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Medicinal Chemistry of Inhibiting RING-Type E3 Ubiquitin Ligases von Blaquiere, Nicole, Villemure, Elisia, Staben, Steven T

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Tactics and Strategies for the Synthesis of Cereblon Ligands von Villemure, Elisia, Wang, Yong, Zhou, Yuebiao, Wong, Alice R., Nilewski, Christian

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Exploring Electrochemical C(sp3)–H Oxidation for the Late-Stage Methylation of Complex Molecules von Novaes, Luiz F. T, Ho, Justin S. K, Mao, Kaining, Liu, Kaida, Tanwar, Mayank, Neurock, Matthew, Villemure, Elisia, Terrett, Jack A, Lin, Song

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Regioselective aliphatic C–H functionalization using frustrated radical pairs von Lu, Zhipeng, Ju, Minsoo, Wang, Yi, Meinhardt, Jonathan M., Martinez Alvarado, Jesus I., Villemure, Elisia, Terrett, Jack A., Lin, Song

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α,β-Desaturation and Formal β‑C(sp3)–H Fluorination of N‑Substituted Amines: A Late-Stage Functionalization Strategy Enabled by Electrochemistry von Novaes, Luiz F. T., Ho, Justin S. K., Mao, Kaining, Villemure, Elisia, Terrett, Jack A., Lin, Song

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C2, C5, and C4 Azole N-Oxide Direct Arylation Including Room-Temperature Reactions von Campeau, Louis-Charles, Bertrand-Laperle, Mégan, Leclerc, Jean-Philippe, Villemure, Elisia, Gorelsky, Serge, Fagnou, Keith

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Heteroaryl Glutarimides and Dihydrouracils as Cereblon Ligand Scaffolds for Molecular Glue Degrader Discovery von Zhou, Yuebiao, Garrigues, Star L., Villemure, Elisia, Ishisoko, Noriko, Nguyen, Huy Q., Hamidi, Nikkia K., Vogt, Rebecca, Wang, Yong, Blake, Robert A., Rudolph, Joachim, Nilewski, Christian

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TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism von Chernov-Rogan, Tania, Gianti, Eleonora, Liu, Chang, Villemure, Elisia, Cridland, Andrew P., Hu, Xiaoyu, Ballini, Elisa, Lange, Wienke, Deisemann, Heike, Li, Tianbo, Ward, Stuart I., Hackos, David H., Magnuson, Steven, Safina, Brian, Klein, Michael L., Volgraf, Matthew, Carnevale, Vincenzo, Chena, Jun

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Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic E... von Terrett, Jack A, Chen, Huifen, Shore, Daniel G, Villemure, Elisia, Larouche-Gauthier, Robin, Déry, Martin, Beaumier, Francis, Constantineau-Forget, Léa, Grand-Maître, Chantal, Lépissier, Luce, Ciblat, Stéphane, Sturino, Claudio, Chen, Yong, Hu, Baihua, Lu, Aijun, Wang, Yunli, Cridland, Andrew P, Ward, Stuart I, Hackos, David H, Reese, Rebecca M, Shields, Shannon D, Chen, Jun, Balestrini, Alessia, Riol-Blanco, Lorena, Lee, Wyne P, Liu, John, Suto, Eric, Wu, Xiumin, Zhang, Juan, Ly, Justin Q, La, Hank, Johnson, Kevin, Baumgardner, Matt, Chou, Kang-Jye, Rohou, Alexis, Rougé, Lionel, Safina, Brian S, Magnuson, Steven, Volgraf, Matthew

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Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design von Volgraf, Matthew, Sellers, Benjamin D, Jiang, Yu, Wu, Guosheng, Ly, Cuong Q, Villemure, Elisia, Pastor, Richard M, Yuen, Po-wai, Lu, Aijun, Luo, Xifeng, Liu, Mingcui, Zhang, Shun, Sun, Liang, Fu, Yuhong, Lupardus, Patrick J, Wallweber, Heidi J.A, Liederer, Bianca M, Deshmukh, Gauri, Plise, Emile, Tay, Suzanne, Reynen, Paul, Herrington, James, Gustafson, Amy, Liu, Yichin, Dirksen, Akim, Dietz, Matthias G. A, Liu, Yanzhou, Wang, Tzu-Ming, Hanson, Jesse E, Hackos, David, Scearce-Levie, Kimberly, Schwarz, Jacob B

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TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism (vol 116, pg 26008, 2019) von Chernov-Rogan, Tania, Gianti, Eleonora, Liu, Chang, Villemure, Elisia, Cridland, Andrew P., Hu, Xiaoyu, Ballini, Elisa, Lange, Wienke, Deisemann, Heike, Li, Tianbo, Ward, Stuart I., Hackos, David H., Magnuson, Steven, Safina, Brian, Klein, Michael L., Volgraf, Matthew, Carnevale, Vincenzo, Chen, Jun

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A Retrospective Look at the Impact of Binding Site Environment on the Optimization of TRPA1 Antagonists von Villemure, Elisia, Terrett, Jack A, Larouche-Gauthier, Robin, Déry, Martin, Chen, Huifen, Reese, Rebecca M, Shields, Shannon D, Chen, Jun, Magnuson, Steven, Volgraf, Matthew

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Discovery of a Potent (4R,5S)‑4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modelin... von Chen, Huifen, Volgraf, Matthew, Do, Steven, Kolesnikov, Aleksandr, Shore, Daniel G, Verma, Vishal A, Villemure, Elisia, Wang, Lan, Chen, Yong, Hu, Baihua, Lu, Ai-Jun, Wu, Guosheng, Xu, Xiaofeng, Yuen, Po-wai, Zhang, Yamin, Erickson, Shawn D, Dahl, Martin, Brotherton-Pleiss, Christine, Tay, Suzanne, Ly, Justin Q, Murray, Lesley J, Chen, Jun, Amm, Desiree, Lange, Wienke, Hackos, David H, Reese, Rebecca M, Shields, Shannon D, Lyssikatos, Joseph P, Safina, Brian S, Estrada, Anthony A

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ATF6 promotes colorectal cancer growth and stemness by regulating the Wnt pathway von Rodvold, Jeffrey J, Grimmer, Matthew, Ruiz, Karen, Marsters, Scot A, Oikonomidi, Ioanna, Tan-Aristy, Eileen, Pham, Victoria C, Sarkar, Tamal, Harnoss, Jonathan M, Shatz-Binder, Whitney, Modrusan, Zora D, Wu, Thomas D, Lill, Jennie R, Villemure, Elisia, Rudolph, Joachim, de Sousa E Melo, Felipe, Ashkenazi, Avi

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Discovery of Hepatitis C Virus NS3-4A Protease Inhibitors with Improved Barrier to Resistance and Favorable Liver Distribution von Moreau, Benoît, O’Meara, Jeff A., Bordeleau, Josée, Garneau, Michel, Godbout, Cedrickx, Gorys, Vida, Leblanc, Mélissa, Villemure, Elisia, White, Peter W., Llinàs-Brunet, Montse

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GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile von Villemure, Elisia, Volgraf, Matthew, Jiang, Yu, Wu, Guosheng, Ly, Cuong Q, Yuen, Po-wai, Lu, Aijun, Luo, Xifeng, Liu, Mingcui, Zhang, Shun, Lupardus, Patrick J, Wallweber, Heidi J. A, Liederer, Bianca M, Deshmukh, Gauri, Plise, Emile, Tay, Suzanne, Wang, Tzu-Ming, Hanson, Jesse E, Hackos, David H, Scearce-Levie, Kimberly, Schwarz, Jacob B, Sellers, Benjamin D

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Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11β-HSD1 inhibitors von Rew, Yosup, McMinn, Dustin L., Wang, Zhulun, He, Xiao, Hungate, Randall W., Jaen, Juan C., Sudom, Athena, Sun, Daqing, Tu, Hua, Ursu, Stefania, Villemure, Elisia, Walker, Nigel P.C., Yan, Xuelei, Ye, Qiuping, Powers, Jay P.

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THERAPEUTIC COMPOUNDS von VILLEMURE, Elisia, RUDOLPH, Joachim, ZENG, Mingshuo

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