Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL von Dumas, Pierre-Yves, Naudin, Cécile, Martin-Lannerée, Séverine, Izac, Brigitte, Casetti, Luana, Mansier, Olivier, Rousseau, Benoît, Artus, Alexandre, Dufossée, Mélody, Giese, Alban, Dubus, Pierre, Pigneux, Arnaud, Praloran, Vincent, Bidet, Audrey, Villacreces, Arnaud, Guitart, Amélie, Milpied, Noël, Kosmider, Olivier, Vigon, Isabelle, Desplat, Vanessa, Dusanter-Fourt, Isabelle, Pasquet, Jean-Max

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Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3 -ITD Acute Myeloid Leukemia von Dumas, Pierre-Yves, Villacreces, Arnaud, Guitart, Amélie V, El-Habhab, Ali, Massara, Layal, Mansier, Olivier, Bidet, Audrey, Martineau, Delphine, Fernandez, Solene, Leguay, Thibaut, Pigneux, Arnaud, Vigon, Isabelle, Pasquet, Jean-Max, Desplat, Vanessa

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Targeting Tyrosine Kinases in Acute Myeloid Leukemia: Why, Who and How? von Fernandez, Solène, Desplat, Vanessa, Villacreces, Arnaud, Guitart, Amélie V, Milpied, Noël, Pigneux, Arnaud, Vigon, Isabelle, Pasquet, Jean-Max, Dumas, Pierre-Yves

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HOXC4 homeoprotein efficiently expands human hematopoietic stem cells and triggers similar molecular alterations as HOXB4 von AUVRAY, Céline, DELAHAYE, Andrée, VIGON, Isabelle, PFLUMIO, Frangoise, HADDAD, Rima, AMSELLEM, Sophie, MIRI-NEZHAD, Ayda, BROIX, Loïc, YACIA, Azzedine, BULLE, Frédérique, FICHELSON, Serge

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PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells von Naudin, Cécile, Hattabi, Aurore, Michelet, Fabio, Miri-Nezhad, Ayda, Benyoucef, Aissa, Pflumio, Françoise, Guillonneau, François, Fichelson, Serge, Vigon, Isabelle, Dusanter-Fourt, Isabelle, Lauret, Evelyne

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Efficient in vitro myogenic reprogramming of human primary mesenchymal stem cells and endothelial cells by Myf5 von Dimicoli-Salazar, Sophie, Bulle, Frederique, Yacia, Azzedine, Massé, Jean-Marc, Fichelson, Serge, Vigon, Isabelle

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3120 – DECIPHERING HEMATOPOIETIC STEM CELLS METABOLISM DURING EXPANSION von Lauvinerie, Claire, Villacreces, Arnaud, Desplat, Vanessa, Dumas, Pierre-Yves, Vigon, Isabelle, Pasquet, Jean-Max, Guitart, Amélie

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3084 – DECIPHERING HEMATOPOIETIC STEM CELLS METABOLISM DURING EXPANSION von Lauvinerie, Claire, Villacreces, Arnaud, Desplat, Vanessa, Dumas, Pierre-Yves, Vigon, Isabelle, Pasquet, Jean-Max, Guitart, Amélie

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HYR, an extracellular module involved in cellular adhesion and related to the immunoglobulin-like fold von CALLEBAUT, ISABELLE, GILGÈS, DELPHINE, VIGON, ISABELLE, MORNON, JEAN-PAUL

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Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3 -ITD Acute Myeloid Leukemia von Dumas, Pierre-Yves, Villacreces, Arnaud, Guitart, Amélie, El-Habhab, Ali, Massara, Layal, Mansier, Olivier, Bidet, Audrey, Martineau, Delphine, Fernandez, Solene, Leguay, Thibaut, Pigneux, Arnaud, Vigon, Isabelle, Pasquet, Jean-Max, Desplat, Vanessa

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A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors von Souyri, Michèle, Vigon, Isabelle, Penciolelli, Jean-François, Heard, Jean-Michel, Tambourin, Pierre, Wendling, Françoise

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Autophagy Targeting and Hematological Mobilization in FLT3-ITD Acute Myeloid Leukemia Decrease Repopulating Capacity and Relapse by Inducing Apoptosis of Committed Leukemic Cells von Dupont, Marine, Huart, Mathilde, Lauvinerie, Claire, Bidet, Audrey, Guitart, Amélie Valérie, Villacreces, Arnaud, Vigon, Isabelle, Desplat, Vanessa, El Habhab, Ali, Pigneux, Arnaud, Ivanovic, Zoran, Brunet De la Grange, Philippe, Dumas, Pierre-Yves, Pasquet, Jean-Max

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CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia von Gioia, Romain, Trégoat, Claire, Dumas, Pierre-Yves, Lagarde, Valérie, Prouzet-Mauléon, Valérie, Desplat, Vanessa, Sirvent, Audrey, Praloran, Vincent, Lippert, Eric, Villacreces, Arnaud, Leconet, Wilhem, Robert, Bruno, Vigon, Isabelle, Roche, Serge, Mahon, François-Xavier, Pasquet, Jean-Max

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Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence von Ianniciello, Angela, Dumas, Pierre-Yves, Drullion, Claire, Guitart, Amélie, Villacreces, Arnaud, Peytour, Yan, Chevaleyre, Jean, Brunet de la Grange, Philippe, Vigon, Isabelle, Desplat, Vanessa, Priault, Muriel, Sbarba, Persio Dello, Ivanovic, Zoran, Mahon, François-Xavier, Pasquet, Jean-Max

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Neuraminidase enhances in vitro expansion of human erythroid progenitors von Bodivit, Gwellaouen, Chadebech, Philippe, Vigon, Isabelle, Yacia, Azzedine, Roziers, Nicolas Burin Des, Pirenne, France, Fichelson, Serge

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Neuraminidase enhances in vitro expansion of human erythroid progenitors von Bodivit, Gwellaouen, Chadebech, Philippe, Vigon, Isabelle, Yacia, Azzedine, Roziers, Nicolas Burin Des, Pirenne, France, Fichelson, Serge

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Neuraminidase enhances in vitro expansion of human erythroid progenitors von Bodivit, Gwellaouen, Chadebech, Philippe, Vigon, Isabelle, Yacia, Azzedine, Roziers, Nicolas Burin des, Pirenne, France, Fichelson, Serge

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CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia: CBL controls kinase expression von Gioia, Romain, Trégoat, Claire, Dumas, Pierre-Yves, Lagarde, Valérie, Prouzet-Mauléon, Valérie, Desplat, Vanessa, Sirvent, Audrey, Praloran, Vincent, Lippert, Eric, Villacreces, Arnaud, Leconet, Wilhem, Robert, Bruno, Vigon, Isabelle, Roche, Serge, Mahon, François-Xavier, Pasquet, Jean-Max

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The HOXB4 Homeoprotein Differentially Promotes Ex Vivo Expansion of Early Human Lymphoid Progenitors von Haddad, Rima, Pflumio, Françoise, Vigon, Isabelle, Visentin, Géraldine, Auvray, Céline, Fichelson, Serge, Amsellem, Sophie

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Molecular Cloning and Characterization of MPL, the Human Homolog of the v-mpl Oncogene: Identification of a Member of the Hematopoietic Growth Factor Receptor Superfamily von Vigon, Isabelle, Mornon, Jean-Paul, Cocault, Laurence, Mitjavila, Marie-Therese, Tambourin, Pierre, Gisselbrecht, Sylvie, Souyri, Michele

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