The role of the microbiota in inflammation, carcinogenesis, and cancer therapy von Dzutsev, Amiran, Goldszmid, Romina S., Viaud, Sophie, Zitvogel, Laurence, Trinchieri, Giorgio

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Dendritic cell-derived exosomes as immunotherapies in the fight against cancer von Pitt, Jonathan M, Charrier, Mélinda, Viaud, Sophie, André, Fabrice, Besse, Benjamin, Chaput, Nathalie, Zitvogel, Laurence

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The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide von Viaud, Sophie, Saccheri, Fabiana, Mignot, Grégoire, Yamazaki, Takahiro, Daillère, Romain, Hannani, Dalil, Enot, David P., Pfirschke, Christina, Engblom, Camilla, Pittet, Mikael J., Schlitzer, Andreas, Ginhoux, Florent, Apetoh, Lionel, Chachaty, Elisabeth, Woerther, Paul-Louis, Eberl, Gérard, Bérard, Marion, Ecobichon, Chantal, Clermont, Dominique, Bizet, Chantai, Gaboriau-Routhiau, Valérie, Cerf-Bensussan, Nadine, Opolon, Paule, Yessaad, Nadia, Vivier, Eric, Ryffel, Bernhard, Elson, Charles O., Doré, Joël, Kroemer, Guido, Lepage, Patricia, Boneca, Ivo Gomperts, Ghiringhelli, François, Zitvogel, Laurence

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Immunomodulatory effects of cyclophosphamide and implementations for vaccine design von Sistigu, Antonella, Viaud, Sophie, Chaput, Nathalie, Bracci, Laura, Proietti, Enrico, Zitvogel, Laurence

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Dendritic Cell-Derived Exosomes for Cancer Immunotherapy: What's Next? von VIAUD, Sophie, THERY, Clotilde, PLOIX, Stéphanie, TURSZ, Thomas, LAPIERRE, Valérie, LANTZ, Olivier, ZITVOGEL, Laurence, CHAPUT, Nathalie

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IL-18 Induces PD-1: Dependent Immunosuppression in Cancer von TERME, Magali, ULLRICH, Evelyn, PREVOST-BLONDEL, Armelle, KATO, Masashi, SCHULTZE, Joachim L, TARTOUR, Eric, KROEMER, Guido, CHAPUT, Nathalie, ZITVOGEL, Laurence, AYMERIC, Laetitia, MEINHARDT, Kathrin, DESBOIS, Mélanie, DELAHAYE, Nicolas, VIAUD, Sophie, RYFFEL, Bernard, YAGITA, Hideo, KAPLANSKI, Gilles

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Cyclophosphamide induces differentiation of Th17 cells in cancer patients von Viaud, Sophie, Flament, Caroline, Zoubir, Mustapha, Pautier, Patricia, LeCesne, Axel, Ribrag, Vincent, Soria, Jean-Charles, Marty, Virginie, Vielh, Philippe, Robert, Caroline, Chaput, Nathalie, Zitvogel, Laurence

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Cancer-Induced Immunosuppression: IL-18-Elicited Immunoablative NK Cells von TERME, Magalj, ULIRICHL, Evelyn, LIEPING CHEN, MECHERI, Salaheddine, KAPLANSKI, Gilles, PREVOST-BLONDEL, Armelle, KATO, Masashi, SCHULTZE, Joachim L, TARTOUR, Eric, KROEMER, Guido, DEGLI-ESPOSTI, Mariapia, CHAPUT, Nathalie, AYMERIC, Laetitia, ZITVOGEL, Laurence, MEINHARDT, Kathrin, COUDERT, Jerome D, DESBOIS, Melanie, GHIRINGHELLI, François, VIAUD, Sophie, RYFFEL, Bernard, YAGITA, Hideo

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Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC von Besse, Benjamin, Charrier, Mélinda, Lapierre, Valérie, Dansin, Eric, Lantz, Olivier, Planchard, David, Le Chevalier, Thierry, Livartoski, Alain, Barlesi, Fabrice, Laplanche, Agnès, Ploix, Stéphanie, Vimond, Nadège, Peguillet, Isabelle, Théry, Clotilde, Lacroix, Ludovic, Zoernig, Inka, Dhodapkar, Kavita, Dhodapkar, Madhav, Viaud, Sophie, Soria, Jean-Charles, Reiners, Katrin S., Pogge von Strandmann, Elke, Vély, Frédéric, Rusakiewicz, Sylvie, Eggermont, Alexander, Pitt, Jonathan M., Zitvogel, Laurence, Chaput, Nathalie

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Human CD19-specific switchable CAR T-cells are efficacious as constitutively active CAR T-cells but cause less morbidity in a mouse model of human CD19+ malignancy von Pennell, Christopher A, Campbell, Heather, Storlie, Meghan D, Bolivar-Wagers, Sara, Osborn, Mark J, Refaeli, Yosef, Jensen, Michael, Viaud, Sophie, Young, Travis S, Blazar, Bruce R

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Dendritic cell derived-exosomes: biology and clinical implementations von Chaput, Nathalie, Flament, Caroline, Viaud, Sophie, Taieb, Julien, Roux, Stephan, Spatz, Alain, André, Fabrice, LePecq, Jean‐Bernard, Boussac, Muriel, Garin, Jérôme, Amigorena, Sebastian, Théry, Clotilde, Zitvogel, Laurence

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1205 Treatment of Lupus-prone BXSB Mice with a Modulatable CAR T cell System Targeting CD19 von Rimann, Ivo, Huang, Hua, Mace, Parker, Gonzalez-Quintial, Rosana, Laborda, Eduardo, Viaud, Sophie, Mora, Hannah, Theofilopoulos, Argyrios N, Young, Travis S, Kono, Dwight H

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Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα von Viaud, Sophie, Terme, Magali, Flament, Caroline, Taieb, Julien, André, Fabrice, Novault, Sophie, Escudier, Bernard, Robert, Caroline, Caillat-Zucman, Sophie, Tursz, Thomas, Zitvogel, Laurence, Chaput, Nathalie

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Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells von ULLRICH, Evelyn, BONMORT, Mathieu, MIGNOT, Grégoire, CHAPUT, Nathalie, TAIEB, Julien, MENARD, Cédric, VIAUD, Sophie, TURSZ, Thomas, KROEMER, Guido, ZITVOGEL, Laurence

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PD-L1 checkpoint blockade delivered by retroviral replicating vector confers anti-tumor efficacy in murine tumor models von Mitchell, Leah A., Yagiz, Kader, Hofacre, Andrew, Viaud, Sophie, Munday, Anthony W., Espinoza, Fernando Lopez, Mendoza, Daniel, Rodriguez-Aguirre, Maria E., Bergqvist, Simon, Haghighi, Ali, Miner, Marin V., Accomando, William P., Burrascano, Cynthia, Gammon, Dawn, Gruber, Harry E., Jolly, Douglas J., Lin, Amy H.

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An inhibitor of cyclin-dependent kinases suppresses TLR signaling and increases the susceptibility of cancer patients to herpes viridae von Zoubir, Mustapha, Flament, Caroline, Gdoura, Abdelaziz, Bahleda, Rastilav, Litvinova, Elena, Soumelis, Vassili, Conforti, Rosa, Viaud, Sophie, Soria, Jean-Charles, Kroemer, Guido, Zitvogel, Laurence, Chaput, Nathalie

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Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory von Viaud, Sophie, Ma, Jennifer S. Y., Hardy, Ian R., Hampton, Eric N., Benish, Brent, Sherwood, Lance, Nunez, Vanessa, Ackerman, Christopher J., Khialeeva, Elvira, Weglarz, Meredith, Lee, Sung Chang, Woods, Ashley K., Young, Travis S.

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Updated Technology to Produce Highly Immunogenic Dendritic Cell-derived Exosomes of Clinical Grade von Viaud, Sophie, Ploix, Stéphanie, Lapierre, Valérie, Théry, Clotilde, Commere, Pierre-Henri, Tramalloni, Dominique, Gorrichon, Kevin, Virault-Rocroy, Pauline, Tursz, Thomas, Lantz, Olivier, Zitvogel, Laurence, Chaput, Nathalie

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Abstract 4771: The addition of toca 511 and 5-FC to temozolomide improves response in a temozolomide-resistant murine glioblastoma model and correlates with toca 511 dose von Rodriguez-Aguirre, Maria E., Viaud, Sophie, Mendoza, Daniel, Montellano, Tiffany, Ostertag, Derek G., Gruber, Harry, Jolly, Douglas, Bentley, Cornelia

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Updated Technology to Produce Highly Immunogenic Dendritic Cell-derived Exosomes of Clinical Grade: A Critical Role of Interferon-γ von VIAUD, Sophie, PLOIX, Stéphanie, ZITVOGEL, Laurence, CHAPUT, Nathalie, LAPIERRE, Valérie, THERY, Clotilde, COMMERE, Pierre-Henri, TRAMALLONI, Dominique, GORRICHON, Kevin, VIRAULT-ROCROY, Pauline, TURSZ, Thomas, LANTZ, Olivier

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