Apolipoprotein E in Alzheimer's disease and other neurological disorders von Verghese, Philip B, PhD, Castellano, Joseph M, BS, Holtzman, David M, Prof

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ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions von Verghese, Philip B, Castellano, Joseph M, Garai, Kanchan, Wang, Yinong, Jiang, Hong, Shah, Aarti, Bu, Guojun, Frieden, Carl, Holtzman, David M

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Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes von Chung, Won-Suk, Verghese, Philip B., Chakraborty, Chandrani, Joung, Julia, Hyman, Bradley T., Ulrich, Jason D., Holtzman, David M., Barres, Ben A.

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Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism von Ma, Qingyi, Zhao, Zhen, Sagare, Abhay P, Wu, Yingxi, Wang, Min, Owens, Nelly Chuqui, Verghese, Philip B, Herz, Joachim, Holtzman, David M, Zlokovic, Berislav V

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Apolipoprotein E associated with reconstituted high‐density lipoprotein‐like particles is protected from aggregation von Hubin, Ellen, Verghese, Philip B., Nuland, Nico, Broersen, Kerensa

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The PrecivityAD™ test: Accurate and reliable LC-MS/MS assays for quantifying plasma amyloid beta 40 and 42 and apolipoprotein E proteotype for the assessment of brain amyloidosis von Kirmess, Kristopher M., Meyer, Matthew R., Holubasch, Mary S., Knapik, Stephanie S., Hu, Yan, Jackson, Erin N., Harpstrite, Scott E., Verghese, Philip B., West, Tim, Fogelman, Ilana, Braunstein, Joel B., Yarasheski, Kevin E., Contois, John H.

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A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysi... von West, Tim, Kirmess, Kristopher M, Meyer, Matthew R, Holubasch, Mary S, Knapik, Stephanie S, Hu, Yan, Contois, John H, Jackson, Erin N, Harpstrite, Scott E, Bateman, Randall J, Holtzman, David M, Verghese, Philip B, Fogelman, Ilana, Braunstein, Joel B, Yarasheski, Kevin E

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The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid‑β Alters the Kinetics of Amyloid Aggregation von Garai, Kanchan, Verghese, Philip B, Baban, Berevan, Holtzman, David M, Frieden, Carl

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Protocol for a seamless phase 2A-phase 2B randomized double-blind placebo-controlled trial to evaluate the safety and efficacy of benfotiamine in patients with early Alzheimer's di... von Feldman, Howard H, Luchsinger, José A, Léger, Gabriel C, Taylor, Curtis, Jacobs, Diane M, Salmon, David P, Edland, Steven D, Messer, Karen, Revta, Carolyn, Flowers, Sarah A, Jones, Kerry S, Koulman, Albert, Yarasheski, Kevin E, Verghese, Philip B, Venkatesh, Venky, Zetterberg, Henrik, Durant, January, Lupo, Jody-Lynn, Gibson, Gary E

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Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes von Basak, Jacob M., Verghese, Philip B., Yoon, Hyejin, Kim, Jungsu, Holtzman, David M.

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Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation von Achariyar, Thiyagaragan M, Li, Baoman, Peng, Weiguo, Verghese, Philip B, Shi, Yang, McConnell, Evan, Benraiss, Abdellatif, Kasper, Tristan, Song, Wei, Takano, Takahiro, Holtzman, David M, Nedergaard, Maiken, Deane, Rashid

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Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care von Palmqvist, Sebastian, Tideman, Pontus, Mattsson-Carlgren, Niklas, Schindler, Suzanne E, Smith, Ruben, Ossenkoppele, Rik, Calling, Susanna, West, Tim, Monane, Mark, Verghese, Philip B, Braunstein, Joel B, Blennow, Kaj, Janelidze, Shorena, Stomrud, Erik, Salvadó, Gemma, Hansson, Oskar

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Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis von Castellano, Joseph M, Deane, Rashid, Gottesdiener, Andrew J, Verghese, Philip B, Stewart, Floy R, West, Tim, Paoletti, Andrew C, Kasper, Tristan R, DeMattos, Ronald B, Zlokovic, Berislav V, Holtzman, David M

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In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis von Ulrich, Jason D, Burchett, Jack M, Restivo, Jessica L, Schuler, Dorothy R, Verghese, Philip B, Mahan, Thomas E, Landreth, Gary E, Castellano, Joseph M, Jiang, Hong, Cirrito, John R, Holtzman, David M

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microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain von Kim, Jaekwang, Yoon, Hyejin, Horie, Takahiro, Burchett, Jack M, Restivo, Jessica L, Rotllan, Noemi, Ramírez, Cristina M, Verghese, Philip B, Ihara, Masafumi, Hoe, Hyang-Sook, Esau, Christine, Fernández-Hernando, Carlos, Holtzman, David M, Cirrito, John R, Ono, Koh, Kim, Jungsu

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Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17-21 P Ameliorates Alzheimer’s Disease Related Pathology and Cognitive Decline von Liu, Shan, Park, Shinae, Allington, Grant, Prelli, Frances, Sun, Yanjie, Martá-Ariza, Mitchell, Scholtzova, Henrieta, Biswas, Goutam, Brown, Bernard, Verghese, Philip B., Mehta, Pankaj D., Kwon, Yong-Uk, Wisniewski, Thomas

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Correction: Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism von Ma, Qingyi, Zhao, Zhen, Sagare, Abhay P, Wu, Yingxi, Wang, Min, Owens, Nelly Chuqui, Verghese, Philip B, Herz, Joachim, Holtzman, David M, Zlokovic, Berislav V

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Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis von Terwel, Dick, Steffensen, Knut R, Verghese, Philip B, Kummer, Markus P, Gustafsson, Jan-Åke, Holtzman, David M, Heneka, Michael T

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Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis von Kim, Jungsu, Eltorai, Adam E M, Jiang, Hong, Liao, Fan, Verghese, Philip B, Kim, Jaekwang, Stewart, Floy R, Basak, Jacob M, Holtzman, David M

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A Systematic Review of Hepatitis E Virus Infection in Children von Verghese, Valsan Philip, Robinson, Joan L.

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