Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins von Schaer, Dominik J., Buehler, Paul W., Alayash, Abdu I., Belcher, John D., Vercellotti, Gregory M.

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Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease von Belcher, John D., Chen, Chunsheng, Nguyen, Julia, Milbauer, Liming, Abdulla, Fuad, Alayash, Abdu I., Smith, Ann, Nath, Karl A., Hebbel, Robert P., Vercellotti, Gregory M.

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Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth von WEGIEL, Barbara, GALLO, David, PANDOLFI, Pier Paolo, HELCZYNSKI, Leszek, BJARTELL, Anders, PERSSON, Jenny Liao, OTTERBEIN, Leo E, CSIZMADIA, Eva, HARRIS, Clair, BELCHER, John, VERCELLOTTI, Gregory M, PENACHO, Nuno, SETH, Pankaj, SUKHATME, Vikas, AHMED, Asif

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Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction von Belcher, John D, Chen, Chunsheng, Nguyen, Julia, Abdulla, Fuad, Zhang, Ping, Nguyen, Hao, Nguyen, Phong, Killeen, Trevor, Miescher, Sylvia M, Brinkman, Nathan, Nath, Karl A, Steer, Clifford J, Vercellotti, Gregory M

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SARS-CoV-2 severity in African Americans - a role for Duffy null? von Hebbel, Robert P., Vercellotti, Gregory M.

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Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia von Belcher, John D, Gomperts, Edward, Nguyen, Julia, Chen, Chunsheng, Abdulla, Fuad, Kiser, Zachary M, Gallo, David, Levy, Howard, Otterbein, Leo E, Vercellotti, Gregory M

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First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia von Cooley, Sarah, He, Fiona, Bachanova, Veronika, Vercellotti, Gregory M., DeFor, Todd E., Curtsinger, Julie M., Robertson, Paul, Grzywacz, Bartosz, Conlon, Kevin C., Waldmann, Thomas A., McKenna, David H., Blazar, Bruce R., Weisdorf, Daniel J., Miller, Jeffrey S.

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A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease von McArthur, James G., Svenstrup, Niels, Chen, Chunsheng, Fricot, Aurelie, Carvalho, Caroline, Nguyen, Julia, Phong Nguyen, Parachikova, Anna, Abdulla, Fuad, Vercellotti, Gregory M., Hermine, Olivier, Edwards, Dave, Ribeil, Jean-Antoine, Belcher, John D., Maciel, Thiago T.

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Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins von Nath, Karl A, Belcher, John D, Nath, Meryl C, Grande, Joseph P, Croatt, Anthony J, Ackerman, Allan W, Katusic, Zvonimir S, Vercellotti, Gregory M

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Therapeutic strategies for sickle cell disease: towards a multi-agent approach von Telen, Marilyn J., Malik, Punam, Vercellotti, Gregory M.

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Red Cells, Hemoglobin, Heme, Iron, and Atherogenesis von Nagy, Emőke, Eaton, John W, Jeney, Viktória, Soares, Miguel P, Varga, Zsuzsa, Galajda, Zoltán, Szentmiklósi, József, Méhes, Gábor, Csonka, Tamás, Smith, Ann, Vercellotti, Gregory M, Balla, György, Balla, József

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Identification of a Heme Activation Site on the MD-2/TLR4 Complex von Belcher, John D., Zhang, Ping, Nguyen, Julia, Kiser, Zachary M., Nath, Karl A., Hu, Jianjun, Trent, John O., Vercellotti, Gregory M.

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Blood–Nanoparticle Interactions and in Vivo Biodistribution: Impact of Surface PEG and Ligand Properties von Shah, Neha B, Vercellotti, Gregory M, White, James G, Fegan, Adrian, Wagner, Carston R, Bischof, John C

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Endothelial TLR4 Expression Mediates Vaso-Occlusive Crisis in Sickle Cell Disease von Beckman, Joan D., Abdullah, Fuad, Chen, Chunsheng, Kirchner, Rachel, Rivera-Rodriguez, Dormarie, Kiser, Zachary M., Nguyen, Aithanh, Zhang, Ping, Nguyen, Julia, Hebbel, Robert P., Belcher, John D., Vercellotti, Gregory M.

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Pro-oxidant and cytotoxic effects of circulating heme von Jeney, Viktória, Balla, József, Yachie, Akihiro, Varga, Zsuzsa, Vercellotti, Gregory M., Eaton, John W., Balla, György

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Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells von Zhang, Ping, Nguyen, Julia, Abdulla, Fuad, Nelson, Alexander T., Beckman, Joan D., Vercellotti, Gregory M., Belcher, John D.

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Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease von Vercellotti, Gregory M, Zhang, Ping, Nguyen, Julia, Abdulla, Fuad, Chen, Chunsheng, Nguyen, Phong, Nowotny, Carlos, Steer, Clifford J, Smith, Ann, Belcher, John D

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Endothelial cell provenance: an unclear role in transplant medicine von Pace, Autumn, Steiner, Marie E, Vercellotti, Gregory M, Somani, Arif

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Correction of Fanconi Anemia Mutations Using Digital Genome Engineering von Sipe, Christopher J, Kluesner, Mitchell G, Bingea, Samuel P, Lahr, Walker S, Andrew, Aneesha A, Wang, Minjing, DeFeo, Anthony P, Hinkel, Timothy L, Laoharawee, Kanut, Wagner, John E, MacMillan, Margaret L, Vercellotti, Gregory M, Tolar, Jakub, Osborn, Mark J, McIvor, R Scott, Webber, Beau R, Moriarity, Branden S

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The multifaceted role of ischemia/reperfusion in sickle cell anemia von Hebbel, Robert P., Belcher, John D., Vercellotti, Gregory M.

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