Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders von Gurney, Mark E, Nugent, Richard A, Mo, Xuesheng, Sindac, Janice A, Hagen, Timothy J, Fox, David, O’Donnell, James M, Zhang, Chong, Xu, Ying, Zhang, Han-Ting, Groppi, Vincent E, Bailie, Marc, White, Ronald E, Romero, Donna L, Vellekoop, A. Samuel, Walker, Joel R, Surman, Matthew D, Zhu, Lei, Campbell, Robert F

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2-Trifluoroacetyl aminoindoles as useful intermediates for the preparation of 2-acylamino indoles von Mangette, John E., Chen, Xuemei, Krishnamoorthy, Ravi, Samuel Vellekoop, A., Csakai, Adam J., Camara, Fatoumata, Paquette, William D., Wang, Hong-Jun, Takahashi, Hidenori, Fleck, Roman, Roth, Gregory P.

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Synthesis and SAR development of novel P2X₇ receptor antagonists for the treatment of pain: Part 2 von Brumfield, Stephanie, Matasi, Julius J, Tulshian, Deen, Czarniecki, Michael, Greenlee, William, Garlisi, Charles, Qiu, Hongchen, Devito, Kristine, Chen, Shu-Cheng, Sun, Yongliang, Bertorelli, Rosalia, Ansell, Justin, Geiss, William, Le, Van-Duc, Martin, Gregory S, Vellekoop, Samuel A, Haber, James, Allard, Melissa L

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Discovery of potent macrocyclic HCV NS5A inhibitors von Yu, Wensheng, Vibulbhan, Bancha, Rosenblum, Stuart B., Martin, Gregory S., Vellekoop, A. Samuel, Holst, Christian L., Coburn, Craig A., Wong, Michael, Selyutin, Oleg, Ji, Tao, Zhong, Bin, Hu, Bin, Chen, Lei, Dwyer, Michael P., Jiang, Yueheng, Nair, Anilkumar G., Tong, Ling, Zeng, Qingbei, Agrawal, Sony, Carr, Donna, Rokosz, Laura, Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Ingravallo, Paul, Lahser, Fred, Asante-Appiah, Ernest, Fells, James, Kozlowski, Joseph A.

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4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors von Pechulis, Anthony D., Beck, James P., Curry, Matt A., Wolf, Mark A., Harms, Arthur E., Xi, Ning, Opalka, Chet, Sweet, Mark P., Yang, Zhicai, Vellekoop, A. Samuel, Klos, Andrew M., Crocker, Peter J., Hassler, Carla, Laws, Mia, Kitchen, Douglas B., Smith, Mark A., Olson, Richard E., Liu, Shuang, Molino, Bruce F.

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Synthesis and SAR development of novel P2X₇ receptor antagonists for the treatment of pain: Part 1 von Matasi, Julius J, Brumfield, Stephanie, Tulshian, Deen, Czarnecki, Michael, Greenlee, William, Garlisi, Charles G, Qiu, Hongchen, Devito, Kristine, Chen, Shu-Cheng, Sun, Youngliang, Bertorelli, Rosalia, Geiss, William, Le, Van-Duc, Martin, Gregory S, Vellekoop, Samuel A, Haber, James, Allard, Melissa L

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A new chemical tool for exploring the physiological function of the PDE2 isozyme von Chambers, Robert J., Abrams, Kristin, Garceau, Norman Y., Kamath, Ajith V., Manley, Christopher M., Lilley, Susan C., Otte, Douglas A., Scott, Dennis O., Sheils, Alissa L., Tess, David A., Vellekoop, A. Samuel, Zhang, Yan, Lam, Kelvin T.

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Preparation of Chiral Oxazolidin-2-ones and Vicinal Amino Alcohols von Takacs, James M, Jaber, Mohamad R, Vellekoop, A. Samuel

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The Mechanism of Organocuprate 1,4-Addition Reactions with .alpha.,.beta.-Unsaturated Ketones: Formation of Cuprate-Enone Complexes with Lithium Dimethylcuprate von Vellekoop, A. Samuel, Smith, Robin A. J

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갑상선 호르몬 유사체의 중간체로서 6--2H-피리다진-3-온 및 6--2H-피리다진-3-온 유도체의 제조 공정 von CONFALONE PASQUALE N, VELLEKOOP A. SAMUEL

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Synthesis and SAR development of novel P2X 7 receptor antagonists for the treatment of pain: Part 1 von Matasi, Julius J., Brumfield, Stephanie, Tulshian, Deen, Czarnecki, Michael, Greenlee, William, Garlisi, Charles G., Qiu, Hongchen, Devito, Kristine, Chen, Shu-Cheng, Sun, Youngliang, Bertorelli, Rosalia, Geiss, William, Le, Van-Duc, Martin, Gregory S., Vellekoop, Samuel A., Haber, James, Allard, Melissa L.

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PROCESS FOR THE PREPARATION OF 6-(4-NITRO-PHENOXY)-2H-PYRIDAZIN-3-ONE AND 6-(4-AMINO-PHENOXY)-2H-PYRIDAZIN-3-ONE DERIVATIVES AS INTERMEDIATES OF THYROID HORMONE ANALOGUES von CONFALONE, Pasquale N, VELLEKOOP, A. Samuel

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Synthesis and SAR development of novel P2X sub(7 receptor antagonists for the treatment of pain: Part 1) von Matasi, Julius J, Brumfield, Stephanie, Tulshian, Deen, Czarnecki, Michael, Greenlee, William, Garlisi, Charles G, Qiu, Hongchen, Devito, Kristine, Chen, Shu-Cheng, Sun, Youngliang, Bertorelli, Rosalia, Geiss, William, Le, Van-Duc, Martin, Gregory S, Vellekoop, Samuel A, Haber, James, Allard, Melissa L

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METHODS FOR PREPARING PYRIDAZINONE DERIVATIVES von CONFALONE, Pasquale N, VELLEKOOP, A. Samuel

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PROCESS FOR THE PREPARATION OF 6-(4-NITRO-PHENOXY)-2H-PYRIDAZIN-3-ONE AND 6-(4-AMINO-PHENOXY)-2H-PYRIDAZIN-3-ONE DERIVATIVES AS INTERMEDIATES OF THYROID HORMONE ANALOGUES von CONFALONE, Pasquale N, VELLEKOOP, A. Samuel

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PROCESS FOR THE PREPARATION OF 6-(4-NITRO-PHENOXY)-2H-PYRIDAZIN-3-ONE AND 6-(4-AMINO-PHENOXY)-2H-PYRIDAZIN-3-ONE DERIVATIVES AS INTERMEDIATES OF THYROID HORMONE ANALOGUES von CONFALONE, Pasquale N, VELLEKOOP, A. Samuel

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Synthesis and SAR development of novel P2X 7 receptor antagonists for the treatment of pain: Part 2 von Brumfield, Stephanie, Matasi, Julius J., Tulshian, Deen, Czarniecki, Michael, Greenlee, William, Garlisi, Charles, Qiu, Hongchen, Devito, Kristine, Chen, Shu-Cheng, Sun, Yongliang, Bertorelli, Rosalia, Ansell, Justin, Geiss, William, Le, Van-Duc, Martin, Gregory S., Vellekoop, Samuel A., Haber, James, Allard, Melissa L.

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New Copper Chemistry. 23. Preparation of Ethereal Lithium Dimethylcuprates (Me2CuLi)2 and Me2CuLi.cntdot.LiI Displaying Narrow Line Width 13C NMR Resonances von Bertz, Steven H, Vellekoop, A. Samuel, Smith, Robin A. J, Snyder, James P

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PROCESS FOR THE PREPARATION OF 6-(4-NITRO-PHENOXY)-2H-PYRIDAZIN-3-ONE AND 6-(4-AMINO-PHENOXY)-2H-PYRIDAZIN-3-ONE DERIVATIVES AS INTERMEDIATES OF THYROID HORMONE ANALOGUES von CONFALONE, Pasquale N, VELLEKOOP, A. Samuel

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PROCESS FOR THE PREPARATION OF 6-(4-NITRO-PHENOXY)-2H-PYRIDAZIN-3-ONE AND 6-(4-AMINO-PHENOXY)-2H-PYRIDAZIN-3-ONE DERIVATIVES AS INTERMEDIATES OF THYROID HORMONE ANALOGUES von CONFALONE, PASQUALE N, VELLEKOOP, A. SAMUEL

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