Identification of (R)‑N‑((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)‑1H‑indole-3-carboxamide (CPI-1205),... von Vaswani, Rishi G, Gehling, Victor S, Dakin, Les A, Cook, Andrew S, Nasveschuk, Christopher G, Duplessis, Martin, Iyer, Priyadarshini, Balasubramanian, Srividya, Zhao, Feng, Good, Andrew C, Campbell, Robert, Lee, Christina, Cantone, Nico, Cummings, Richard T, Normant, Emmanuel, Bellon, Steven F, Albrecht, Brian K, Harmange, Jean-Christophe, Trojer, Patrick, Audia, James E, Zhang, Ying, Justin, Neil, Chen, Shuyang, Wilson, Jon R, Gamblin, Steven J

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Acyl-Chain Methyl Distributions of Liquid-Ordered and -Disordered Membranes von Mihailescu, Mihaela, Vaswani, Rishi G., Jardón-Valadez, Eduardo, Castro-Román, Francisco, Freites, J. Alfredo, Worcester, David L., Chamberlin, A. Richard, Tobias, Douglas J., White, Stephen H.

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Stereocontrolled Total Synthesis of (−)-Kaitocephalin von Vaswani, Rishi G, Chamberlin, A. Richard

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Progress Toward the Total Synthesis of (±)-Actinophyllic Acid von Vaswani, Rishi G, Day, Joshua J, Wood, John L

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Discovery of Benzotriazolo[4,3‑d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains von Taylor, Alexander M, Vaswani, Rishi G, Gehling, Victor S, Hewitt, Michael C, Leblanc, Yves, Audia, James E, Bellon, Steve, Cummings, Richard T, Côté, Alexandre, Harmange, Jean-Christophe, Jayaram, Hari, Joshi, Shivangi, Lora, Jose M, Mertz, Jennifer A, Neiss, Adrianne, Pardo, Eneida, Nasveschuk, Christopher G, Poy, Florence, Sandy, Peter, Setser, Jeremy W, Sims, Robert J, Tang, Yong, Albrecht, Brian K

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Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials von Albrecht, Brian K, Gehling, Victor S, Hewitt, Michael C, Vaswani, Rishi G, Côté, Alexandre, Leblanc, Yves, Nasveschuk, Christopher G, Bellon, Steve, Bergeron, Louise, Campbell, Robert, Cantone, Nico, Cooper, Michael R, Cummings, Richard T, Jayaram, Hariharan, Joshi, Shivangi, Mertz, Jennifer A, Neiss, Adrianne, Normant, Emmanuel, O’Meara, Michael, Pardo, Eneida, Poy, Florence, Sandy, Peter, Supko, Jeffrey, Sims, Robert J, Harmange, Jean-Christophe, Taylor, Alexander M, Audia, James E

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Harnessing the Power of Catalysis for the Synthesis of CRTH2 Antagonist MK-1029 von Ruck, Rebecca T, Pan, Jun, Vaswani, Rishi G, Kosjek, Birgit, Strotman, Neil A, Cai, Chaoxian, Humphrey, Guy R

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Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (−)-kaitocephalin von Vaswani, Rishi G., Limon, Agenor, Reyes-Ruiz, Jorge Mauricio, Miledi, Ricardo, Chamberlin, A. Richard

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Discovery, design, and synthesis of indole-based EZH2 inhibitors von Gehling, Victor S., Vaswani, Rishi G., Nasveschuk, Christopher G., Duplessis, Martin, Iyer, Priyadarshini, Balasubramanian, Srividya, Zhao, Feng, Good, Andrew C., Campbell, Robert, Lee, Christina, Dakin, Les A., Cook, Andrew S., Gagnon, Alexandre, Harmange, Jean-Christophe, Audia, James E., Cummings, Richard T., Normant, Emmanuel, Trojer, Patrick, Albrecht, Brian K.

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A Practical Synthesis of Indoles via a Pd-Catalyzed C–N Ring Formation von Vaswani, Rishi G, Albrecht, Brian K, Audia, James E, Côté, Alexandre, Dakin, Les A, Duplessis, Martin, Gehling, Victor S, Harmange, Jean-Christophe, Hewitt, Michael C, Leblanc, Yves, Nasveschuk, Christopher G, Taylor, Alexander M

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Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors von Gehling, Victor S, McGrath, John P, Duplessis, Martin, Khanna, Avinash, Brucelle, Francois, Vaswani, Rishi G, Côté, Alexandre, Stuckey, Jacob, Watson, Venita, Cummings, Richard T, Balasubramanian, Srividya, Iyer, Priyadarshini, Sawant, Priyanka, Good, Andrew C, Albrecht, Brian K, Harmange, Jean-Christophe, Audia, James E, Bellon, Steven F, Trojer, Patrick, Levell, Julian R

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Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors von Gehling, Victor S, Hewitt, Michael C, Vaswani, Rishi G, Leblanc, Yves, Côté, Alexandre, Nasveschuk, Christopher G, Taylor, Alexander M, Harmange, Jean-Christophe, Audia, James E, Pardo, Eneida, Joshi, Shivangi, Sandy, Peter, Mertz, Jennifer A, Sims, Robert J, Bergeron, Louise, Bryant, Barbara M, Bellon, Steve, Poy, Florence, Jayaram, Hariharan, Sankaranarayanan, Ravichandran, Yellapantula, Sreegouri, Bangalore Srinivasamurthy, Nandana, Birudukota, Swarnakumari, Albrecht, Brian K

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EZH2 Inhibitor Efficacy in Non-Hodgkin’s Lymphoma Does Not Require Suppression of H3K27 Monomethylation von Bradley, William D., Arora, Shilpi, Busby, Jennifer, Balasubramanian, Srividya, Gehling, Victor S., Nasveschuk, Christopher G., Vaswani, Rishi G., Yuan, Chih-Chi, Hatton, Charlie, Zhao, Feng, Williamson, Kaylyn E., Iyer, Priyadarshini, Méndez, Jacqui, Campbell, Robert, Cantone, Nico, Garapaty-Rao, Shivani, Audia, James E., Cook, Andrew S., Dakin, Les A., Albrecht, Brian K., Harmange, Jean-Christophe, Daniels, Danette L., Cummings, Richard T., Bryant, Barbara M., Normant, Emmanuel, Trojer, Patrick

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Development of methyl isoxazoleazepines as inhibitors of BET von Hewitt, Michael C, Leblanc, Yves, Gehling, Victor S, Vaswani, Rishi G, Côté, Alexandre, Nasveschuk, Christopher G, Taylor, Alexander M, Harmange, Jean-Christophe, Audia, James E, Pardo, Eneida, Cummings, Rich, Joshi, Shivangi, Sandy, Peter, Mertz, Jennifer A, Sims, 3rd, Robert J, Bergeron, Louise, Bryant, Barbara M, Bellon, Steve, Poy, Florence, Jayaram, Hariharan, Jayaran, Hariharan, Tang, Yong, Albrecht, Brian K

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Welwitindolinone C synthetic studies. Construction of the welwitindolinone carbon skeleton via a transannular nitrone cycloaddition von Freeman, David B., Holubec, Alexandra A., Weiss, Matthew W., Dixon, Julie A., Kakefuda, Akio, Ohtsuka, Masami, Inoue, Munenori, Vaswani, Rishi G., Ohki, Hidenori, Doan, Brian D., Reisman, Sarah E., Stoltz, Brian M., Day, Joshua J., Tao, Ran N., Dieterich, Noah A., Wood, John L.

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Kaitocephalin Antagonism of Glutamate Receptors Expressed in Xenopus Oocytes von Limon, Agenor, Reyes-Ruiz, Jorge M, Vaswani, Rishi G, Chamberlin, A. Richard, Miledi, Ricardo

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Abstract 1224: Discovery of novel BAF inhibitors for the treatment of transcription factor-driven cancers von Centore, Richard C., Soares, Luis M., Vaswani, Rishi G., Ichikawa, Kana, Li, Zhifang, Fan, Hong, Setser, Jeremy, Lahr, David L., Zawadzke, Laura, Chen, Xueying, Barnash, Kimberly D., Muwanguzi, Jordana, Anthony, Neville, Sandoval, Gabriel J., Feldman, Katharine, Adam, Ammar, Huang, David, Schiller, Shawn, Wilson, Kevin, Voigt, Johannes, Hentemann, Martin, Millan, David S., Chan, Ho Man, Bellon, Steven F., Decicco, Carl P., Xu, Lan

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Identification of ( R )- N -((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1 H -indole-3-carboxamide (CPI-1... von Vaswani, Rishi G., Gehling, Victor S., Dakin, Les A., Cook, Andrew S., Nasveschuk, Christopher G., Duplessis, Martin, Iyer, Priyadarshini, Balasubramanian, Srividya, Zhao, Feng, Good, Andrew C., Campbell, Robert, Lee, Christina, Cantone, Nico, Cummings, Richard T., Normant, Emmanuel, Bellon, Steven F., Albrecht, Brian K., Harmange, Jean-Christophe, Trojer, Patrick, Audia, James E., Zhang, Ying, Justin, Neil, Chen, Shuyang, Wilson, Jon R., Gamblin, Steven J.

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Abstract LB190: Modulation of SPI1 transcriptional program contributes to the preclinical anti-tumor activity of SMARCA4/SMARCA2 ATPase inhibitors in AML von Sandoval, Gabriel J., Feldman, Katharine, Topal, Sal, Adam, Ammar, Wu, Hsin-Jung, Sappal, Darshan, Soares, Luis M., Lahr, David L., Xu, Lan, Vaswani, Rishi G., Muwanguzi, Jordana, Huang, Liyue, Piel, Jessica, Collins, Mike, Chan, Ho Man, Thomenius, Michael J., Bellon, Steven F., Kruger, Ryan G., Decicco, Carl P., Centore, Richard C., Hentemann, Martin

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ChemInform Abstract: A Practical Synthesis of Indoles via a Pd-Catalyzed C-N Ring Formation von Vaswani, Rishi G., ., et al

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